Cited by 164Ovarian function and disordersEndometriosis Research and TreatmentAdolescent and Pediatric Healthcare

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Quality of Life in Adolescent Girls With Polycystic Ovary Syndrome

Trent, Maria E., Rich, Michael, Austin, S. Bryn, Gordon, Catherine M.·2002·Archives of Pediatrics & Adolescent Medicine

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Abstract

OBJECTIVES: To examine health-related quality of life (HRQL) in adolescents with polycystic ovary syndrome (PCOS), compared with healthy adolescents, and to determine whether clinically observed or self-perceived severity of illness affects their HRQL. DESIGN AND SETTING: Cross-sectional study of female adolescents conducted at an urban, hospital-based adolescent medicine clinical practice. PARTICIPANTS: Ninety-seven adolescent patients with PCOS and 186 healthy patients who were seen for care between October 15, 1999, and March 2, 2001. MAIN OUTCOME MEASURES: Health-related quality-of-life scores as determined by the Child Health Questionnaire-Child Self-Report Form. RESULTS: Adolescents with PCOS scored lower on subscales measuring general health perceptions, physical functioning, general behavior, and limitations in family activities because of illness. Patients scored higher on the change in health in the last year subscale, and most had been diagnosed and initiated treatment for PCOS in the last year. Patients who had higher self-perceived severity of illness also scored lower on the general health perceptions subscale, but clinical severity was not associated with differences in HRQL. CONCLUSIONS: Adolescents with PCOS experience lower HRQL compared with healthy adolescents. Polycystic ovary syndrome and perceived severity of illness negatively affect HRQL in adolescents. This study suggests a need to develop interventions to reduce the distress that patients with PCOS may face as adolescents and young adults.

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Authors: Trent, M. E., Rich, M., Austin, S. B., & Gordon, C. M.
Affiliations: Johns Hopkins University (US)
Harvard University (US)
Corresponding author: Trent, Maria E.
ORCID: Trent, Maria E.
Rich, Michael
Austin, S. Bryn
Gordon, Catherine M.
Venue: Archives of Pediatrics & Adolescent Medicine
Publisher: American Medical Association (AMA)
Published: 2002-06-01
Volume: 156
Issue: 6
Pages: 556
ISSN: 1072-4710 (ISSN-L)
DOI: 10.1001/archpedi.156.6.556
OpenAlex: W2123357728
Cited by: 164
References: 18
Citations by year: 2025: 5 · 2024: 5 · 2023: 7 · 2022: 9 · 2021: 4 · 2020: 13 · 2019: 11 · 2018: 7 · 2017: 4 · 2016: 3 · 2015: 6 · 2014: 12 · 2013: 3 · 2012: 9
FWCI: 6.09
Type: journal article
Language: en
Open access: closed
Locations: Archives of Pediatrics and Adolescent Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: U.S. Public Health Service (6T71MC00009-09S1R0)
Topics: Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Adolescent and Pediatric Healthcare
Keywords: polycystic ovary syndrome, health-related quality of life, adolescent girls, perceived illness severity, clinical severity, Child Health Questionnaire, physical function, adolescent medicine
MeSH terms: Adolescent, Adult, Cross-Sectional Studies, Female, Humans, Polycystic Ovary Syndrome, Quality of Life, Surveys and Questionnaires, Severity of Illness Index

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Quality of Life in Adolescent Girls With Polycystic Ovary Syndrome

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