PCOS in Adolescence and Type 2 Diabetes

Carreau, Anne-Marie; Baillargeon, Jean-Patrice

doi:10.1007/s11892-014-0564-3

Cited by 40Ovarian function and disordersDiabetes, Cardiovascular Risks, and LipoproteinsGestational Diabetes Research and Management

PCOS in Adolescence and Type 2 Diabetes

Carreau, Anne-Marie, Baillargeon, Jean-Patrice·2015·Current Diabetes Reports

DOI 10.1007/s11892-014-0564-3

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Abstract

Polycystic ovary syndrome is a frequent disorder in women of reproductive age that consists of a heterogeneous combination of hyperandrogenism, chronic anovulation, and polycystic ovaries. Hyperandrogenism and anovulation are clearly linked to insulin resistance and compensatory hyperinsulinism, with an ovarian androgenic hyperresponsiveness to circulating insulin. Evidence is increasing that suggests that lipotoxicity, which is a key mechanism in the development of insulin resistance and type 2 diabetes, could also explain the androgen overproduction. During adolescence, diagnosis of polycystic ovarian syndrome (PCOS) may be difficult but is of importance because PCOS increases future risk of type 2 diabetes and metabolic complications. Metabolic perturbations begin early in adolescence and also exist in adolescent relatives of women with PCOS, even before clinical signs of PCOS. Screening for impaired glucose tolerance or type 2 diabetes is also important in this population, and treatment should focus on PCOS clinical manifestations as well as long-term metabolic risk.

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Compensatory hyperinsulinemia commonly observed in PCOS significantly contributes to the progression of the disorder.
“Compensatory hyperinsulinemia, which is commonly observed in individuals with PCOS [49–51], significantly contributes to the progression of the disorder.”
From Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management (2025) · cites this paper as [51]

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
(2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.10.004 · Cited by 9,050 · see citing works
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group (2004) · Human Reproduction · doi:10.1093/humrep/deh098 · Cited by 6,138 · see citing works
The Diagnosis of Polycystic Ovary Syndrome during Adolescence
Witchel, S. F., Oberfield, S., Rosenfield, R. L., Codner, E., Bonny, A., Ibáñez, L., Pena, A., Horikawa, R., Gomez-Lobo, V., Joel, D., et al. (2015) · Hormone Research in Paediatrics · doi:10.1159/000375530 · Cited by 3,113 · see citing works
The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population
Azziz, R., Woods, K. S., Reyna, R., Key, T. J., Knochenhauer, E. S., & Yıldız, B. O. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032046 · Cited by 2,715 · see citing works
Clinical assessment of body hair growth in women.
Ferriman, D., & Gallwey, J. D. (1961) · Journal of Clinical Endocrinology and Metabolism · doi:10.1210/jcem-21-11-1440 · Cited by 2,556 · see citing works
Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline
Azziz, R., Carmina, E., Dewailly, D., Diamanti-Kandarakis, E., Escobar-Morreale, H. F., Futterweit, W., Janssen, O. E., Legro, R. S., Norman, R. J., Taylor, A. E., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0178 · Cited by 2,143 · see citing works
Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
Diamanti-Kandarakis, E., & Dunaif, A. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1034 · Cited by 1,947 · see citing works
Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
Legro, R. S., Arslanian, S. A., Ehrmann, D. A., Hoeger, K. M., Murad, M. H., Pasquali, R., & Welt, C. K. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2350 · Cited by 1,919 · see citing works
Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
Legro, R. S. (1999) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.1.165 · Cited by 1,743 · see citing works
Prevalence of the Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study1
Knochenhauer, E. S., Key, T. J., Kahsar-Miller, M., Waggoner, W., Boots, L. R., & Azziz, R. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.9.5090 · Cited by 1,568 · see citing works
A Prospective Study of the Prevalence of the Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain1
Asunción, M., Calvo, R. M., Millán, J. L. S., Sancho, J., Ávila, S., & Escobar-Morreale, H. F. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6682 · Cited by 1,328 · see citing works
Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome.
Ehrmann, D. A., Barnes, R. B., Rosenfield, R. L., Cavaghan, M. K., & Imperial, J. (1999) · Diabetes Care · doi:10.2337/diacare.22.1.141 · Cited by 1,257 · see citing works
Full accounting of diabetes and pre-diabetes in the U.S. population in 1988–1994 and 2005–2006
Cowie, C. C., Rust, K. F., Ford, E. S., Eberhardt, M. S., Byrd-Holt, D. D., Li, C., Williams, D. E., Gregg, E. W., Bainbridge, K. E., Saydah, S. H., et al. (2009) · Diabetes Care · doi:10.2337/dc08-1296 · Cited by 1,154 · see citing works
A Survey of the Polycystic Ovary Syndrome in the Greek Island of Lesbos: Hormonal and Metabolic Profile
Diamanti‐Kandarakis, E., Kouli, C., Bergiele, A. T., Filandra, F. A., Tsianateli, T. C., Spina, G., Zapanti, E. D., & Bartzis, M. I. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.11.6148 · Cited by 1,107 · see citing works
Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with the Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society
Wild, R. A., Carmina, E., Diamanti-Kandarakis, E., Dokras, A., Escobar-Morreale, H. F., Futterweit, W., Lobo, R., Norman, R. J., Talbott, E., & Dumesic, D. A. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2724 · Cited by 1,010 · see citing works
Thrombotic stroke and myocardial infarction with hormonal contraception
Lidegaard, Ø., Løkkegaard, E., Jensen, A., Skovlund, C. W., & Keiding, N. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1111840 · Cited by 607 · see citing works
Premature Adrenarche - A Common Condition with Variable Presentation
Utriainen, P., Laakso, S. M., Liimatta, J., Jääskeläinen, J., & Voutilainen, R. (2015) · Hormone Research in Paediatrics · doi:10.1159/000369458 · Cited by 477 · see citing works
Definition, epidemiology and classification of diabetes in children and adolescents
Craig, M. E., Hattersley, A. T., & Donaghue, K. C. (2009) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2009.00568.x · Cited by 463 · see citing works
Adolescent Girls with Polycystic Ovary Syndrome Have an Increased Risk of the Metabolic Syndrome Associated with Increasing Androgen Levels Independent of Obesity and Insulin Resistance
Coviello, A. D., Legro, R. S., & Dunaif, A. E. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1666 · Cited by 446 · see citing works
Polycystic ovaries and associated clinical and biochemical features in young women
Michelmore, K. F., Balen, A. H., Dunger, D. B., & Vessey, M. P. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00886.x · Cited by 433 · see citing works
Impact of Obesity on the Risk for Polycystic Ovary Syndrome
Yildiz, B. O., Knochenhauer, E. S., & Azziz, R. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1834 · Cited by 401 · see citing works
Adipose Tissue Has Aberrant Morphology and Function in PCOS: Enlarged Adipocytes and Low Serum Adiponectin, but Not Circulating Sex Steroids, Are Strongly Associated with Insulin Resistance
Mannerås-Holm, L., Leonhardt, H., Kullberg, J., Jennische, E., Odén, A., Holm, G., Hellström, M., Lönn, L., Olivecrona, G., Stener-Victorin, E., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1290 · Cited by 369 · see citing works
Screening for Abnormal Glucose Tolerance in Adolescents with Polycystic Ovary Syndrome
Palmert, M. R., Gordon, C. M., Kartashov, A. I., Legro, R. S., Emans, S. J., & Dunaif, A. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.3.8305 · Cited by 354 · see citing works
The diagnosis of polycystic ovary syndrome in adolescents
Carmina, E., Oberfield, S. E., & Lobo, R. A. (2010) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.03.008 · Cited by 339 · see citing works
POSITION STATEMENT: Glucose Intolerance in Polycystic Ovary Syndrome—A Position Statement of the Androgen Excess Society
Salley, K. E. S., Wickham, E. P., Cheang, K. I., Essah, P. A., Karjane, N. W., & Nestler, J. E. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1549 · Cited by 339 · see citing works
Suppression of Serum Insulin by Diazoxide Reduces Serum Testosterone Levels in Obese Women with Polycystic Ovary Syndrome*
NESTLER, J. E., BARLASCINI, C. O., MATT, D. W., STEINGOLD, K. A., PLYMATE, S. R., CLORE, J. N., & BLACKARD, W. G. (1989) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-68-6-1027 · Cited by 338 · see citing works
Metabolic Syndrome Rates in United States Adolescents, from the National Health and Nutrition Examination Survey, 1999–2002
Cook, S., Auinger, P., Li, C., & Ford, E. S. (2008) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2007.06.004 · Cited by 325 · see citing works
Changes in Glucose Tolerance over Time in Women with Polycystic Ovary Syndrome: A Controlled Study
Legro, R. S., Gnatuk, C. L., Kunselman, A. R., & Dunaif, A. E. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1843 · Cited by 308 · see citing works
Effects of metformin and rosiglitazone, alone and in combination, in nonobese women with polycystic ovary syndrome and normal indices of insulin sensitivity
Baillargeon, J.-P., Jakubowicz, D. J., Iuorno, M. J., Jakubowicz, S., & Nestler, J. E. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.02.127 · Cited by 300 · see citing works
Self-citation
Association between the Current Use of Low-Dose Oral Contraceptives and Cardiovascular Arterial Disease: A Meta-Analysis
Baillargeon, J., McClish, D. K., Essah, P. A., & Nestler, J. E. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1958 · Cited by 298 · see citing works
Self-citation
Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome
Lewy, V. D., Danadian, K., Witchel, S. F., & Arslanian, S. (2001) · The Journal of Pediatrics · doi:10.1067/mpd.2001.109603 · Cited by 298 · see citing works
Development of Age-Specific Adolescent Metabolic Syndrome Criteria That Are Linked to the Adult Treatment Panel III and International Diabetes Federation Criteria
Jolliffe, C. J., & Janssen, I. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.08.065 · Cited by 292 · see citing works
Thrombotic Stroke and Myocardial Infarction With Hormonal Contraception
Lidegaard, Ø., Løkkegaard, E., Jensen, A., Skovlund, C. W., & Keiding, N. (2012) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000422965.64164.ac · Cited by 292 · see citing works
Metformin Therapy in Obese Adolescents with Polycystic Ovary Syndrome and Impaired Glucose Tolerance: Amelioration of Exaggerated Adrenal Response to Adrenocorticotropin with Reduction of Insulinemia/Insulin Resistance
Arslanian, S. A., Lewy, V., Danadian, K., & Saad, R. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.4.8398 · Cited by 272 · see citing works
Restoration of Reproductive Potential by Lifestyle Modification in Obese Polycystic Ovary Syndrome: Role of Insulin Sensitivity and Luteinizing Hormone
Huber-Buchholz, M.-M. (1999) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.4.1470 · Cited by 269 · see citing works
Glucose Intolerance in Obese Adolescents with Polycystic Ovary Syndrome: Roles of Insulin Resistance and β-Cell Dysfunction and Risk of Cardiovascular Disease1
Arslanian, S. A., Lewy, V. D., & Danadian, K. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7123 · Cited by 268 · see citing works
Adiponectin levels in women with polycystic ovary syndrome: a systematic review and a meta-analysis
Toulis, K. A., Goulis, D. G., Farmakiotis, D., Georgopoulos, N. A., Katsikis, I., Tarlatzis, B. C., Papadimas, I., & Panidis, D. (2009) · Human Reproduction Update · doi:10.1093/humupd/dmp006 · Cited by 262 · see citing works
Metabolic and Reproductive Features before and during Puberty in Daughters of Women with Polycystic Ovary Syndrome
Sir-Petermann, T., Codner, E., Pérez, V., Echiburú, B., Maliqueo, M., Ladrón de Guevara, A., Preisler, J., Crisosto, N., Sánchez, F., Cassorla, F., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2836 · Cited by 260 · see citing works
The impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women in two randomized, placebo-controlled clinical trials
Hoeger, K., Davidson, K., Kochman, L., Cherry, T., Kopin, L., & Guzick, D. S. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0461 · Cited by 256 · see citing works
Instability in the Diagnosis of Metabolic Syndrome in Adolescents
Goodman, E., Daniels, S. R., Meigs, J. B., & Dolan, L. M. (2007) · Circulation · doi:10.1161/circulationaha.106.669994 · Cited by 241 · see citing works
Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome
Costello, M. F., Shrestha, B., Eden, J., Johnson, N., & Moran, L. J. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005552.pub2 · Cited by 197 · see citing works
Referral Bias in Defining the Phenotype and Prevalence of Obesity in Polycystic Ovary Syndrome
Ezeh, U., Yildiz, B. O., & Azziz, R. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1295 · Cited by 193 · see citing works
The genetics of the polycystic ovary syndrome
Urbanek, M. (2007) · Nature Clinical Practice Endocrinology &#38 Metabolism · doi:10.1038/ncpendmet0400 · Cited by 185 · see citing works
Clinical, ultrasound and biochemical features of polycystic ovary syndrome in adolescents: implications for diagnosis
Hickey, M., Doherty, D. A., Atkinson, H. C., Sloboda, D. M., Franks, S., Norman, R. J., & Hart, R. J. (2011) · Human Reproduction · doi:10.1093/humrep/der102 · Cited by 170 · see citing works
Prevalence of polycystic ovary syndrome in adolescents
Christensen, S. B., Black, M. H., Smith, N., Martinez, M. M., Jacobsen, S. J., Porter, A. H., & Koebnick, C. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.04.001 · Cited by 168 · see citing works
Quality of life in adolescent girls with polycystic ovary syndrome
Trent, M. E., Rich, M., Austin, S. B., & Gordon, C. M. (2002) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.156.6.556 · Cited by 164 · see citing works
Effect of Lifestyle Intervention on Features of Polycystic Ovarian Syndrome, Metabolic Syndrome, and Intima-Media Thickness in Obese Adolescent Girls
Lass, N., Kleber, M., Winkel, K., Wunsch, R., & Reinehr, T. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1609 · Cited by 160 · see citing works
Genetics of the polycystic ovary syndrome
Kosova, G., & Urbanek, M. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.10.009 · Cited by 156 · see citing works
Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS)11The full text of this article is available via JAH Online at http://www.elsevier.com/locate/jahonline.
Glueck, C. J., Wang, P., Fontaine, R. N., Tracy, T., & Sieve-Smith, L. (2001) · Journal of Adolescent Health · doi:10.1016/s1054-139x(01)00202-6 · Cited by 153 · see citing works
Adrenal Androgen Excess in the Polycystic Ovary Syndrome: Sensitivity and Responsivity of the Hypothalamic-Pituitary-Adrenal Axis1
Azziz, R., Black, V. Y., Hines, G. A., Fox, L. M., & Boots, L. R. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.7.4948 · Cited by 153 · see citing works
Comparison of Efficacy of Spironolactone with Metformin in the Management of Polycystic Ovary Syndrome: An Open-Labeled Study
Ganie, M. A., Khurana, M. L., Eunice, M., Gulati, M., Dwivedi, S. N., & Ammini, A. C. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031780 · Cited by 151 · see citing works
Early Metabolic Derangements in Daughters of Women with Polycystic Ovary Syndrome
Sir‐Petermann, T., Maliqueo, M. A., Ethel Codner, D., Echiburú, B., Crisosto, N., Pérez, V., Pérez‐Bravo, F., & CASSORLA, F. G. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1036 · Cited by 151 · see citing works
Risk of T2DM and impaired fasting glucose among pcos subjects: Results of an 8-year follow-up
Boudreaux, M. Y., Talbott, E. O., Kip, K. E., Brooks, M. M., & Witchel, S. F. (2006) · Current Diabetes Reports · doi:10.1007/s11892-006-0056-1 · Cited by 139 · see citing works
Adolescent Anovulation: Maturational Mechanisms and Implications
Rosenfield, R. L. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1770 · Cited by 139 · see citing works
Androgen and lipid profiles in adolescents with polycystic ovary syndrome who were treated with two forms of combined oral contraceptives
Mastorakos, G., Koliopoulos, C., & Creatsas, G. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)02993-x · Cited by 137 · see citing works
Insulin Sensitizers for Polycystic Ovary Syndrome
Baillargeon, J., Iuorno, M. J., & Nestler, J. E. (2003) · Clinical Obstetrics & Gynecology · doi:10.1097/00003081-200306000-00011 · Cited by 132 · see citing works
Self-citation
Adipose Tissue Dysfunction in Polycystic Ovary Syndrome
Villa, J., & Pratley, R. E. (2011) · Current Diabetes Reports · doi:10.1007/s11892-011-0189-8 · Cited by 130 · see citing works
Randomized Placebo-Controlled Trial of Metformin for Adolescents With Polycystic Ovary Syndrome
Bridger, T., MacDonald, S., Baltzer, F., & Rodd, C. (2006) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.160.3.241 · Cited by 126 · see citing works
Health-related quality of life among adolescents with polycystic ovary syndrome
Jones, G. L., Hall, J. M., Lashen, H. L., Balen, A. H., & Ledger, W. L. (2011) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1111/j.1552-6909.2011.01279.x · Cited by 124 · see citing works
Insulin Sensitization for Girls with Precocious Pubarche and with Risk for Polycystic Ovary Syndrome: Effects of Prepubertal Initiation and Postpubertal Discontinuation of Metformin Treatment
Ibáñez, L., Valls, C., Marcos, M. V., Ong, K. K., Dunger, D. B., & de Zegher, F. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0463 · Cited by 123 · see citing works
Early Metformin Therapy (Age 8–12 Years) in Girls with Precocious Pubarche to Reduce Hirsutism, Androgen Excess, and Oligomenorrhea in Adolescence
Ibáñez, L., López-Bermejo, A., Díaz, M., Marcos, M. V., & de Zegher, F. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0555 · Cited by 123 · see citing works
Prevalence of type 2 diabetes mellitus and impaired glucose tolerance in Asian women with polycystic ovary syndrome
Weerakiet, S., Srisombut, C., Bunnag, P., Sangtong, S., Chuangsoongnoen, N., & Rojanasakul, A. (2001) · International Journal of Gynecology & Obstetrics · doi:10.1016/s0020-7292(01)00477-5 · Cited by 120 · see citing works
Prevalence of Metabolic Syndrome and Related Characteristics in Obese Adolescents with and without Polycystic Ovary Syndrome
Rossi, B., Sukalich, S., Droz, J., Griffin, A., Cook, S., Blumkin, A., Guzick, D. S., & Hoeger, K. M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1198 · Cited by 120 · see citing works
Treatment of Hirsutism, Hyperandrogenism, Oligomenorrhea, Dyslipidemia, and Hyperinsulinism in Nonobese, Adolescent Girls: Effect of Flutamide
Ibáñez, L., Potau, N., Marcos, M. V., & de Zegher, F. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.9.6814 · Cited by 117 · see citing works
Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity
Baillargeon, J., & Carpentier, A. C. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.12.055 · Cited by 116 · see citing works
Self-citation
Polycystic ovarian morphology in postmenarchal adolescents
Codner, E., Villarroel, C., Eyzaguirre, F. C., López, P., Merino, P. M., Pérez-Bravo, F., Iñiguez, G., & Cassorla, F. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.06.015 · Cited by 113 · see citing works
Adipose tissue expandability and the early origins of PCOS
de Zegher, F., López‐Bermejo, A., & Ibáñez, L. (2009) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2009.06.003 · Cited by 108 · see citing works
Circulating levels of adipose products and differences in fat distribution in the ovulatory and anovulatory phenotypes of polycystic ovary syndrome
Carmina, E., Bucchieri, S., Mansueto, P., Rini, G., Ferin, M., & Løbo, R. A. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.03.007 · Cited by 103 · see citing works
Functional Significance of Polycystic-Size Ovaries in Healthy Adolescents
Mortensen, M., Rosenfield, R. L., & Littlejohn, E. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0835 · Cited by 103 · see citing works
A very large proportion of young Danish women have polycystic ovaries: is a revision of the Rotterdam criteria needed?
Kristensen, S. L., Ramlau-Hansen, C. H., Ernst, E., Olsen, S. F., Bonde, J. P., Vested, A., & Toft, G. (2010) · Human Reproduction · doi:10.1093/humrep/deq273 · Cited by 102 · see citing works
Effects of two forms of combined oral contraceptives on carbohydrate metabolism in adolescents with polycystic ovary syndrome
Mastorakos, G. P., Koliopoulos, C., Deligeoroglou, E., Diamanti‐Kandarakis, E., & Creatsas, G. K. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.07.1306 · Cited by 102 · see citing works
Metformin treatment is effective in obese teenage girls with PCOS
Leo, V. D. (2006) · Human Reproduction · doi:10.1093/humrep/del185 · Cited by 101 · see citing works
Clinical expression of polycystic ovary syndrome in adolescent girls
Sultan, C., & Paris, F. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.04.015 · Cited by 92 · see citing works
PCOS in adolescents
Diamanti‐Kandarakis, E. (2009) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2009.09.005 · Cited by 91 · see citing works
Randomized controlled trial evaluating response to metformin versus standard therapy in the treatment of adolescents with polycystic ovary syndrome
Allen, H. F., Mazzoni, C., Heptulla, R. A., Murray, M. A., Miller, N., Koenigs, L., & Reiter, E. O. (2005) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2005.18.8.761 · Cited by 90 · see citing works
Effect of weight loss on menstrual function in adolescents with polycystic ovary syndrome
Ornstein, R. M., Copperman, N. M., & Jacobson, M. S. (2011) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2011.01.002 · Cited by 82 · see citing works
Postprandial fatty acid metabolism in the development of lipotoxicity and type 2 diabetes
Carpentier, A. C. (2008) · Diabetes & Metabolism · doi:10.1016/j.diabet.2007.10.009 · Cited by 79 · see citing works
Assessment of glucose metabolism in polycystic ovary syndrome: HbA1c or fasting glucose compared with the oral glucose tolerance test as a screening method
Lerchbaum, E., Schwetz, V., Giuliani, A., & Obermayer-Pietsch, B. (2013) · Human Reproduction · doi:10.1093/humrep/det255 · Cited by 73 · see citing works
State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS)
Geller, D. H., Pacaud, D., Gordon, C. M., & Misra, M. (2011) · International Journal of Pediatric Endocrinology · doi:10.1186/1687-9856-2011-9 · Cited by 71 · see citing works
Polycystic Ovarian Syndrome (PCOS): A Significant Contributor to The Overall Burden of Type 2 Diabetes in Women
Talbott, E. O., Zborowski, J. V., Rager, J. R., Kip, K. E., Xu, X., & Orchard, T. J. (2007) · Journal of Women s Health · doi:10.1089/jwh.2006.0098 · Cited by 56 · see citing works
Intravenous Lipid and Heparin Infusion-Induced Elevation in Free Fatty Acids and Triglycerides Modifies Circulating Androgen Levels in Women: A Randomized, Controlled Trial
Mai, K., Bobbert, T., Reinecke, F., Andres, J., Maser‐Gluth, C., Wudy, S. A., Möhlig, M., Weickert, M. O., Hartmann, M. F., Schulte, H. M., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0714 · Cited by 54 · see citing works
Association Between Polycystic Ovarian Syndrome, Overweight, and Metabolic Syndrome in Adolescents
Rahmanpour, H., Jamal, L., Mousavinasab, S. N., Esmaeilzadeh, A., & Azarkhish, K. (2012) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2012.02.004 · Cited by 52 · see citing works
Suppression of serum insulin level by diazoxide does not alter serum testosterone or sex hormone-binding globulin levels in healthy, nonobese women
Nestler, J. E., Singh, R., Matt, D. W., Clore, J. N., & Blackard, W. G. (1990) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(90)90698-7 · Cited by 51 · see citing works
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Glueck, C. J., Aregawi, D. G., Winiarska, M., Agioria, M., Luo, G., Sieve, L., & Wang, P. (2006) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2006.19.6.831 · Cited by 48 · see citing works
Diagnosis of adolescent polycystic ovary syndrome
Hardy, T., & Norman, R. J. (2013) · Steroids · doi:10.1016/j.steroids.2013.04.011 · Cited by 45 · see citing works
Drospirenone/Ethinyl EstradiolVersusRosiglitazone Treatment in Overweight Adolescents with Polycystic Ovary Syndrome: Comparison of Metabolic, Hormonal, and Cardiovascular Risk Factors
Tfayli, H. M., Ulnach, J. W., Lee, S., Sutton‐Tyrrell, K., & Arslanian, S. A. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2547 · Cited by 44 · see citing works
Influence of a positive family history of both type 2 diabetes and PCOS on metabolic and endocrine parameters in a large cohort of PCOS women
Lerchbaum, E., Theiler‐Schwetz, V., Giuliani, A., & Obermayer-Pietsch, B. M. (2014) · European Journal of Endocrinology · doi:10.1530/eje-13-1035 · Cited by 42 · see citing works
Oral Contraception vs Insulin Sensitization for 18 Months in Nonobese Adolescents With Androgen Excess: Posttreatment Differences in C-Reactive Protein, Intima-Media Thickness, Visceral Adiposity, Insulin Sensitivity, and Menstrual Regularity
Ibáñez, L., Díaz, M., Sebastiani, G., Marcos, M. V., López-Bermejo, A., & de Zegher, F. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1041 · Cited by 42 · see citing works
What do we know about metabolic syndrome in adolescents with PCOS?
Cırık, D. A., & Dilbaz, B. (2014) · Journal of the Turkish-German Gynecological Association · doi:10.5152/jtgga.2014.95776 · Cited by 38 · see citing works
Adipose tissue insulin resistance in peripubertal girls with first-degree family history of polycystic ovary syndrome
Trottier, A., Battista, M., Geller, D. H., Moreau, B., Carpentier, A. C., Simoneau‐Roy, J., & Baillargeon, J. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.08.025 · Cited by 34 · see citing works
Self-citation
The prevalence of upper lip hair in black and white girls during puberty: A new standard
Lucky, A. W., Biro, F. M., Daniels, S. R., Cedars, M. I., Khoury, P. R., & Morrison, J. A. (2001) · The Journal of Pediatrics · doi:10.1067/mpd.2001.109790 · Cited by 33 · see citing works
Suitability of recommended limits for fasting glucose tests in women with polycystic ovary syndrome
Gagnon, C., & Baillargeon, J.-P. (2007) · Canadian Medical Association Journal · doi:10.1503/cmaj.060607 · Cited by 33 · see citing works
Self-citation
Whither PCOS? The Challenges of Establishing Hyperandrogenism in Adolescent Girls
Biro, F. M., & Emans, S. J. (2008) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2008.05.004 · Cited by 32 · see citing works
Adiponectin, Leptin and Ghrelin Levels in Obese Adolescent Girls with Polycystic Ovary Syndrome
GÜRBÜZ, T., Akhan, S. E., Baştu, E., Telci, A., İyibozkurt, A. C., & Topuz, S. (2012) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2012.09.002 · Cited by 29 · see citing works
Polycystic ovary syndrome: evidence for a primary disorder of ovarian steroidogenesis
Franks, S., Gharani, N., & Gilling‐Smith, C. (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(99)00044-8 · Cited by 28 · see citing works
Pioglitazone (7·5 mg/day) added to flutamide–metformin in women with androgen excess: additional increments of visfatin and high molecular weight adiponectin
Ibáñez, L., López‐Bermejo, A., Díaz, M., Enríquez, G., Valls, C., & de Zegher, F. (2007) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2007.03137.x · Cited by 27 · see citing works
Saturated fatty acid exposure induces androgen overproduction in bovine adrenal cells
Bellanger, S., Battista, M., Fink, G. D., & Baillargeon, J. (2012) · Steroids · doi:10.1016/j.steroids.2011.12.017 · Cited by 27 · see citing works
Self-citation
Diagnosing Dysglycemia in Adolescents With Polycystic Ovary Syndrome
Gooding, H. C., Milliren, C., St. Paul, M., Mansfield, M. J., & DiVasta, A. (2014) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2013.12.020 · Cited by 17 · see citing works
Altered glucose disposition and insulin sensitivity in peri-pubertal first-degree relatives of women with polycystic ovary syndrome
Raissouni, N., Kolesnikov, A., Purushothaman, R., SINHA, S. K., Bhandari, S., Bhangoo, A., Malik, S., Mathew, R. P., Baillargeon, J., Hernández, M. I., et al. (2012) · International Journal of Pediatric Endocrinology · doi:10.1186/1687-9856-2012-14 · Cited by 16 · see citing works
Self-citation
Role of Ovary and Adrenal Glands in Hyperandrogenemia in Patients with Polycystic Ovary Syndrome
Kamel, N., Gedik, V. T., Emral, R., Çorapçıoğlu, D., Baştemir, M., & Güllü, S. (2005) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-2004-830540 · Cited by 12 · see citing works
Treatment of Polycystic Ovary Syndrome in Adolescence
Hoeger, K. M., & Vitek, W. (2014) · Seminars in Reproductive Medicine · doi:10.1055/s-0034-1371093 · Cited by 11 · see citing works
Metformin-Diet Ameliorates Coronary Heart Disease Risk Factors and Facilitates Resumption of Regular Menses in Adolescents with Polycystic Ovary Syndrome
Glueck, C. J., Goldenberg, N., & Wang, P. (2009) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2009.22.9.815 · Cited by 10 · see citing works

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Dumesic, D. A., Oberfield, S. E., Stener-Victorin, E., Marshall, J. C., Laven, J. S., & Legro, R. S. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1018 · Cited by 1,020 · see citing works
Polycystic Ovary Syndrome in Insulin-Resistant Adolescents with Obesity: The Role of Nutrition Therapy and Food Supplements as a Strategy to Protect Fertility
Calcaterra, V., Verduci, E., Cena, H., Magenes, V. C., Todisco, C. F., Tenuta, E., Gregorio, C., De Giuseppe, R., Bosetti, A., Di Profio, E., et al. (2021) · Nutrients · doi:10.3390/nu13061848 · Cited by 183 · see citing works
Correlation Between Fecal Metabolomics and Gut Microbiota in Obesity and Polycystic Ovary Syndrome
Zhou, L., Ni, Z., Yu, J., Cheng, W., Cai, Z., & Yu, C. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00628 · Cited by 148 · see citing works
The effects of quercetin supplementation on metabolic and hormonal parameters as well as plasma concentration and gene expression of resistin in overweight or obese women with polycystic ovary syndrome
Khorshidi, M., Moini, A., Alipoor, E., Rezvan, N., Gorgani‐Firuzjaee, S., Yaseri, M., & Hosseinzadeh‐Attar, M. J. (2018) · Phytotherapy Research · doi:10.1002/ptr.6166 · Cited by 112 · see citing works
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Yan, Y., Desvignes, T., Bremiller, R., WILSON, C. A., Dillon, D. M., High, S. K., Draper, B. W., Buck, C. L., & Postlethwait, J. H. (2017) · Developmental Dynamics · doi:10.1002/dvdy.24579 · Cited by 93 · see citing works
Up-regulation of genes involved in the insulin signalling pathway (IGF1, PTEN and IGFBP1) in the endometrium may link polycystic ovarian syndrome and endometrial cancer
Shafiee, M. N., Seedhouse, C., Mongan, N. P., Chapman, C. J., Deen, S., Abu, J., & Atiomo, W. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.01.019 · Cited by 78 · see citing works
The Effect of Nutrient Supplementation in Management of Polycystic Ovary Syndrome Associated Metabolic Dysfunctions: A Critical Review
Günalan, E., Yaba, A., & Yılmaz, B. (2018) · Journal of the Turkish-German Gynecological Association · doi:10.4274/jtgga.2018.0077 · Cited by 74 · see citing works
Genistein exhibits therapeutic potential for PCOS mice via the ER-Nrf2-Foxo1-ROS pathway
Luo, M., Zheng, L., Wang, Y., Huang, J., Yang, Z., Yue, Z., & Guo, B. (2021) · Food & Function · doi:10.1039/d1fo00684c · Cited by 65 · see citing works
Validity of adiponectin-to-leptin and adiponectin-to-resistin ratios as predictors of polycystic ovary syndrome
Sarray, S., Madan, S., Saleh, L. R., Mahmoud, N., & Almawi, W. Y. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.05.007 · Cited by 62 · see citing works
Prevalence of Polycystic Ovary Syndrome in Patients With Pediatric Type 2 Diabetes
Cioana, M., Deng, J., Nadarajah, A., Hou, M., Qiu, Y., Chen, S. S. J., Rivas, A., Banfield, L. E., Alfaraidi, H., Alotaibi, A., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.47454 · Cited by 55 · see citing works
Hibiscus sabdariffa in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
Jamrozik, D., Borymska, W., & Kaczmarczyk-Żebrowska, I. (2022) · Foods · doi:10.3390/foods11142134 · Cited by 47 · see citing works
Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian PCOS model
Sudhakaran, G., Guru, A., Haridevamuthu, B., Murugan, R., Arshad, A., & Arockiaraj, J. (2022) · Life Sciences · doi:10.1016/j.lfs.2021.120276 · Cited by 46 · see citing works
Serum metabolomics reveals metabolic profiling for women with hyperandrogenism and insulin resistance in polycystic ovary syndrome
Zhang, Z., Hong, Y., Chen, M., Tan, N., Liu, S., Nie, X., & Zhou, W. (2020) · Metabolomics · doi:10.1007/s11306-020-1642-y · Cited by 44 · see citing works
Modified Banxia Xiexin Decoction Ameliorates Polycystic Ovarian Syndrome With Insulin Resistance by Regulating Intestinal Microbiota
Zhao, H., Chen, R., Zheng, D., Xiong, F., Jia, F., Liu, J., Zhang, L., Zhang, N., Zhu, S., Liu, Y., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.854796 · Cited by 40 · see citing works
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MicroRNA and Diabetic Complications: A Clinical Perspective
Fan, B., Luk, A. O. Y., Chan, J. C. N., & Ronald, C. W. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7318 · Cited by 37 · see citing works
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Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management
Muhammed Saeed, A. A., Noreen, S., Awlqadr, F. H., Farooq, M. I., Qadeer, M., Rai, N., Farag, H. A., & Saeed, M. N. (2025) · Journal of Health, Population and Nutrition · doi:10.1186/s41043-025-00899-y · Cited by 29 · see citing works
A proteomic analysis identifies candidate early biomarkers to predict ovarian hyperstimulation syndrome in polycystic ovarian syndrome patients
Wu, L., Sun, Y., Wan, J., Luan, T., Cheng, Q., & Tan, Y. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.6604 · Cited by 23 · see citing works
What does a diagnostic label of ‘polycystic ovary syndrome’ really mean in adolescence? a review of current practice recommendations
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Polycystic Ovary Syndrome
Goetsch, A. L., Kimelman, D., & Woodruff, T. K. (2017) · Springer eBooks · doi:10.1007/978-3-319-52316-3_14 · Cited by 14 · see citing works
Causal Association Between BMI and Polycystic Ovarian Syndrome: Bidirectional 2-Sample Mendelian Randomization Study
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Polycystic ovary syndrome in adolescents: a review of past year evidence
Javed, A., Chelvakumar, G., & Bonny, A. E. (2016) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000301 · Cited by 10 · see citing works
Alanine Aminotransferase Is a Marker of Lipotoxicity Consequences and Hyperandrogenemia in Women with Polycystic Ovary Syndrome
Bélan, M., Pelletier, C., & Baillargeon, J. (2017) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2016.0119 · Cited by 7 · see citing works
Self-citation
Clinical Manifestations of Insulin Resistance in Youth
Chen, M. E., & Hannon, T. (2019) · Contemporary endocrinology · doi:10.1007/978-3-030-25057-7_1 · Cited by 2 · see citing works
Features of the course of type 2 diabetes mellitus in young people
Ovsyannikova, A. K., & Zubareva, A. Y. (2022) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2022-16-10-57-61 · Cited by 2 · see citing works
Impact of endocrine disrupting chemicals (EDCs) on the predisposition of cancer and polycystic ovary syndrome (PCOS): A Note
Bhattacharjee, N., Sarkar, S., & Giri, B. (2022) · Journal of Drug Delivery and Therapeutics · doi:10.22270/jddt.v12i5.5582 · Cited by 2 · see citing works
Polycystic Ovary Syndrome in Adolescent Girls
Gupta, S., Pandithurai, E., & Agarwal, A. K. (2016) · Springer eBooks · doi:10.1007/978-3-319-32122-6_16 · Cited by 2 · see citing works
Diagnosis values of three-dimensional power Doppler ultrasonography in polycystic ovary syndrome and its relationship with serum sex hormone levels
Song, L., Shi, L., & Liu, W. (2023) · Steroids · doi:10.1016/j.steroids.2023.109203 · Cited by 2 · see citing works
Influence of endurance training-induced weight loss on the levels of ghrelin and obestatin of obese women with polycystic ovary syndrome
Zehsaz, F., Farhangi, N., & Ghahramani, M. (2020) · Sport Sciences for Health · doi:10.1007/s11332-020-00646-2 · Cited by 2 · see citing works
The Biopsychosocial Model in Type 2 Diabetes Mellitus: A Narrative Review
Khalil, Y., Abu-Khalaf, L., Abu-Khalaf, R., Abu-Khalaf, S., & Al-Balootti, K. (2025) · Cureus · doi:10.7759/cureus.96814 · Cited by 2 · see citing works
Insulin Resistance and Lipotoxicity in PCOS: Causes and Consequences
Carreau, A., Battista, M., & Baillargeon, J. (2022) · Springer eBooks · doi:10.1007/978-3-030-92589-5_8 · Cited by 1 · see citing works
Self-citation
Endocrinologia e Imunologia: O caminho para compreender as doenças metabólicas, hormonais e autoimunes - Edição IX
Freitas, G. B. L. D., EIGENHEER, A. D. V., GUIMARÃES, C. H. C. D. C., Rodrigues, G. W. A., CAPÓSSOLI, L. M., DANTAS, M. H. A. D. S., BRAGA, T. R. D. S. A., & Vascão, E. (2024) · doi:10.59290/978-65-6029-126-3
Genetic Polymorphisms in Polycystic Ovarian Syndrome
Alfahdawi, S. M. S. (2022) · Biomedicine and Chemical Sciences · doi:10.48112/bcs.v1i4.264 · Cited by 1 · see citing works
Comparison of Indices between PCOS and Non-PCOS Patients in Assisted Reproduction
Zhang, Y., Zhang, Y., & Xue, F.-X. (2016) · West Indian Medical Journal · doi:10.7727/wimj.2016.012
ANTHROPOMETRIC MEASUREMENTS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME IN SAUDI ARABIA.
ijar, & Afandi, R. (2018) · International Journal of Advanced Research · doi:10.21474/ijar01/7535
Polycystic Ovary Syndrome and Metabolic Syndrome
Carreau, A., Pesant, M.-H., & Baillargeon, J. (2019) · Contemporary Endocrinology · doi:10.1007/978-3-030-25057-7_16
Self-citation
Type 2 Diabetes Mellitus in Youth
Srinivasan, S., & Levitsky, L. L. (2024) · Springer eBooks · doi:10.1007/978-3-031-66296-6_31
Evaluation of Serum Interleukin-19 level in Women with Polyendocrine Metabolic Ovarian Syndrome
AL-Tai, T. H. H., Al-Saedi, J. A., Al-Hadithi, H. S., & Nadeem, T. (2026) · Journal of the Faculty of Medicine Baghdad · doi:10.32007/jfacmedbaghdad3321

PCOS and Type II Diabetes
Avolio, M., & Ismail, H. M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-55138-0.00010-3
Polycystic ovary syndrome (PCOS) and the accompanying disorders of glucose homeostasis among girls at the time of puberty
Otto-Buczkowska, E., Grzyb, K., & Jainta, N. (2018) · Pediatric Endocrinology Diabetes and Metabolism · doi:10.18544/pedm-24.01.0101 · Cited by 38 · see citing works
Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum
Prosperi, S., & Chiarelli, F. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1669716 · Cited by 38 · see citing works
Type 2 diabetes, polycystic ovary syndrome and the insulin resistance syndrome in adolescents: Are they one big iceberg?
Dean, H., & Sellers, E. A. C. (2002) · Paediatrics & Child Health · doi:10.1093/pch/7.5.333 · Cited by 4 · see citing works
Treatment options of polycystic ovary syndrome in adolescence.
Zapanti, E. D., Kiapekou, E., & Loutradis, D. (2006) · PubMed · Cited by 3 · see citing works

Authors: Carreau, A.-M., & Baillargeon, J.-P.
Affiliations: Université de Sherbrooke (CA)
Corresponding author: Baillargeon, Jean-Patrice
ORCID: Carreau, Anne-Marie
Baillargeon, Jean-Patrice
Venue: Current Diabetes Reports
Publisher: Springer Science and Business Media LLC
Published: 2014-11-11
Volume: 15
Issue: 1
Pages: 564-564
ISSN: 1534-4827 (ISSN-L)
1539-0829
DOI: 10.1007/s11892-014-0564-3
OpenAlex: W2045992292
Cited by: 40
References: 102
Citations by year: 2026: 2 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 8 · 2021: 3 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 5 · 2016: 4 · 2015: 4
FWCI: 0.68
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Current Diabetes Reports (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
Keywords: polycystic ovary syndrome, adolescence, type 2 diabetes, insulin resistance, hyperandrogenism, anovulation, lipotoxicity, impaired glucose tolerance, diabetes screening, metabolic risk
MeSH terms: Adolescent, Blood Glucose, Diabetes Mellitus, Type 2, Diagnosis, Differential, Female, Hirsutism, Humans, Hyperinsulinism, Insulin Resistance, Polycystic Ovary Syndrome, Risk Factors, Ultrasonography, Vagina, Prevalence, Hyperandrogenism, Lipid Metabolism

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PCOS in Adolescence and Type 2 Diabetes

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