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Cited by 270

The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

The Positive-Negative Distinction in Schizophrenia: Review of Natural History Validators

McGlashan, Thomas H.·1992·Archives of General Psychiatry
DOI 10.1001/archpsyc.1992.01820010063008
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Abstract

A review of the interaction between the positive-negative symptom distinction in schizophrenia and multiple measures of illness natural history reveals some redundant and compelling patterns. Negative or deficit symptoms are often associated with inferior social/instrumental functioning premorbidly, more abnormal voluntary/involuntary movements at illness presentation, and poorer long-term outcome when present beyond the early phase of illness. Negative symptoms are semi-independent of positive symptoms. They are variable early in the illness but accrue in severity, stability, and prognostic weight with time. The nature of the processes that generate negative symptoms and their specificity to schizophrenia remain to be elucidated. Nevertheless, it is clear that negative symptoms are a common and valid component of schizophrenia and deserve recognition as such in our nosology.

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Metadata

Authors
McGlashan, T. H.
Venue
Archives of General Psychiatry
Publisher
American Medical Association (AMA)
Published
1992-01-01
Volume
49
Issue
1
Pages
63
ISSN
0003-990X (ISSN-L)
DOI
10.1001/archpsyc.1992.01820010063008
OpenAlex
W2022407796
Cited by
270
References
94
FWCI
20.82
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Positive-Negative Distinction in Schizophrenia: Review of Natural History Validators. https://app.cochat.ai/papers/10.1001/archpsyc.1992.01820010063008
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McGlashan, T. H. (1992). The Positive-Negative Distinction in Schizophrenia: Review of Natural History Validators. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1992.01820010063008

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.