Startle Gating Deficits in a Large Cohort of Patients With Schizophrenia: Relationship to Medications, Symptoms, Neurocognition, and Level of Function

Statistical power analysis for the behavioral sciences

Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417

Dementia Praecox or the Group of Schizophrenias

(1951) · Journal of the American Medical Association · doi:10.1001/jama.1951.02920270079043 · Cited by 4,407

Wechsler Adult Intelligence Scale-III

Ryan, J. J., & Lopez, S. J. (2001) · Springer eBooks · doi:10.1007/978-1-4615-1185-4_2 · Cited by 3,680

Structured Clinical Interview for DSM-IV Axis I Disorders

Spitzer, R. L., First, M. B., & Gibbon, M. (1997) · Medical Entomology and Zoology · Cited by 3,582

What are the functional consequences of neurocognitive deficits in schizophrenia?

(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.3.321 · Cited by 3,516

Unconscious cerebral initiative and the role of conscious will in voluntary action

Libet, B. (1985) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00044903 · Cited by 2,623

Rethinking feelings: an fMRI study of the cognitive regulation of emotion

Ochsner, K. N., Bunge, S. A., Gross, J. J., & Gabrieli, J. D. E. (2002) · Journal of Cognitive Neuroscience · doi:10.1162/089892902760807212 · Cited by 2,520

The prefontral cortex and cognitive control

Miller, E. K. (2000) · Nature Reviews Neuroscience · doi:10.1038/35036228 · Cited by 2,016

Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

BRAFF, D. L., Geyer, M. A., & Swerdlow, N. R. (2001) · Psychopharmacology · doi:10.1007/s002130100810 · Cited by 1,701

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

Geyer, M. A., Krebs-Thomson, K., Braff, D. L., & Swerdlow, N. R. (2001) · Psychopharmacology · doi:10.1007/s002130100811 · Cited by 1,484

Oxytocin: The Great Facilitator of Life

Lee, H.-J., Macbeth, A. H., Pagani, J., & Young, W. S. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.04.001 · Cited by 1,037

Neurophysiological Endophenotypes of Schizophrenia: The Viability of Selected Candidate Measures

Turetsky, B. I., Calkins, M. E., Light, G. A., D, A. O. M., Radant, A. D., & Swerdlow, N. R. (2006) · Schizophrenia Bulletin · doi:10.1093/schbul/sbl060 · Cited by 575

Realistic expectations of prepulse inhibition in translational models for schizophrenia research

Swerdlow, N. R., Weber, M., Qu, Y., Light, G. A., & Braff, D. L. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1072-4 · Cited by 529

Gamma Band Oscillations Reveal Neural Network Cortical Coherence Dysfunction in Schizophrenia Patients

Light, G. A., Hsu, J., Hsieh, M. H., Meyer-Gomes, K., Sprock, J., Swerdlow, N. R., & BRAFF, D. L. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.055 · Cited by 430

Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia

Javitt, D. C., & Freedman, R. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.13121691 · Cited by 403

Initial Heritability Analyses of Endophenotypic Measures for Schizophrenia

Greenwood, T. A., BRAFF, D. L., Light, G. A., Cadenhead, K. S., Calkins, M. E., Dobie, D. J., Freedman, R., Green, M. F., Gur, R. E., Gur, R. C., et al. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.11.1242 · Cited by 382

Neurophysiological biomarkers for drug development in schizophrenia

Javitt, D. C., Spencer, K., Thaker, G. K., Winterer, G., & Hajós, M. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2463 · Cited by 340

Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia

Young, J. W., Powell, S. B., Risbrough, V. B., Marston, H. M., & Geyer, M. A. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.02.004 · Cited by 312

Prenatal stress: Role in psychotic and depressive diseases

Markham, J. A., & Koenig, J. I. (2010) · Psychopharmacology · doi:10.1007/s00213-010-2035-0 · Cited by 282

Top–down modulation of prepulse inhibition of the startle reflex in humans and rats

Li, L., Du, Y., Li, N., Wu, X. H., & Wu, Y. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.02.001 · Cited by 250

Psilocybin-Induced Deficits in Automatic and Controlled Inhibition are Attenuated by Ketanserin in Healthy Human Volunteers

Quednow, B. B., Kometer, M., Geyer, M. A., & Vollenweider, F. X. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.228 · Cited by 240

Prepulse inhibition and genetic mouse models of schizophrenia

Powell, S. B., Zhou, X., & Geyer, M. A. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.04.021 · Cited by 218

Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions

Thyme, S. B., Pieper, L. M., Li, E. H., Pandey, S., Wang, Y., Morris, N. S., Sha, C., Choi, J. W., Herrera, K. J., Soucy, E. R., et al. (2019) · Cell · doi:10.1016/j.cell.2019.01.048 · Cited by 220

The role of the thalamus in schizophrenia from a neuroimaging perspective

Pergola, G., Selvaggi, P., Trizio, S., Bertolino, A., & Blasi, G. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.01.013 · Cited by 203

Preattentive Sensory Processing as Indexed by the MMN and P3a Brain Responses is Associated with Cognitive and Psychosocial Functioning in Healthy Adults

Light, G. A., Swerdlow, N. R., & BRAFF, D. L. (2007) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2007.19.10.1624 · Cited by 188

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Ishiguro, H., Horiuchi, Y., Ishikawa, M., Koga, M., Imai, K., Suzuki, Y., Morikawa, M., Inada, T., Watanabe, Y., Takahashi, M., et al. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.024 · Cited by 188

CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity

Onaivi, E. S., Ishiguro, H., Gu, S., & Liu, Q. (2011) · Journal of Psychopharmacology · doi:10.1177/0269881111400652 · Cited by 190

Mouse behavioral endophenotypes for schizophrenia

Amann, L. C., Gandal, M. J., Halene, T. B., Ehrlichman, R. S., White, S., McCarren, H. S., & Siegel, S. J. (2010) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2010.04.008 · Cited by 180

Sensorimotor gating of the startle reflex: what we said 25 years ago, what has happened since then, and what comes next

Swerdlow, N. R., BRAFF, D. L., & Geyer, M. A. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116661075 · Cited by 186

Endophenotypes in psychiatric genetics

Walters, J., & Owen, M. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002068 · Cited by 174

Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia

Takao, K., Kobayashi, K., Hagihara, H., Ohira, K., Shoji, H., Hattori, S., Koshimizu, H., Umemori, J., Toyama, K., Nakamura, H. K., et al. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.38 · Cited by 173

Future clinical uses of neurophysiological biomarkers to predict and monitor treatment response for schizophrenia

Light, G. A., & Swerdlow, N. R. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12730 · Cited by 158

Prenatal Immune Challenge Is an Environmental Risk Factor for Brain and Behavior Change Relevant to Schizophrenia: Evidence from MRI in a Mouse Model

Li, Q., Cheung, C., Wei, R., Hui, E. S. K., Feldon, J., Meyer, U., Chung, S. K., Chua, S. E., Sham, P. C., Wu, E. X., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006354 · Cited by 152

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Pantelis, C., Yücel, M., Bora, E., Fornito, A., Testa, R., Brewer, W. J., Velakoulis, D., & Wood, S. J. (2009) · Neuropsychology Review · doi:10.1007/s11065-009-9114-1 · Cited by 138

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Quednow, B. B., Frommann, I., Berning, J., Kühn, K.-U., Maier, W., & Wagner, M. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.04.019 · Cited by 135

Association Analysis of 94 Candidate Genes and Schizophrenia-Related Endophenotypes

Greenwood, T. A., Light, G. A., Swerdlow, N. R., Radant, A. D., & BRAFF, D. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029630 · Cited by 134

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Giakoumaki, S. G., Roussos, P., & Bitsios, P. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.82 · Cited by 136

Profile of auditory information-processing deficits in schizophrenia

Turetsky, B. I., Bilker, W. B., Siegel, S. J., Kohler, C. G., & Gur, R. E. (2008) · Psychiatry Research · doi:10.1016/j.psychres.2008.04.013 · Cited by 130

Prepulse Inhibition of the Startle Reflex: A Window on the Brain in Schizophrenia

BRAFF, D. L. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_61 · Cited by 123

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Powell, S. B., Weber, M., & Geyer, M. A. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_195 · Cited by 127

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Managò, F., Mereu, M., Mastwal, S. S., Mastrogiacomo, R., Scheggia, D., Emanuele, M., Luca, M. A. D., Weinberger, D. R., Wang, K. H., & Papaleo, F. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.07.044 · Cited by 119

Neural substrates of normal and impaired preattentive sensory discrimination in large cohorts of nonpsychiatric subjects and schizophrenia patients as indexed by MMN and P3a change detection responses

Takahashi, H., Rissling, A. J., Pascual-Marqui, R. D., Kirihara, K., Pela, M., Sprock, J., BRAFF, D. L., & Light, G. A. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.09.074 · Cited by 117

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Ago, Y., Koda, K., Takuma, K., & Matsuda, T. (2011) · Journal of Pharmacological Sciences · doi:10.1254/jphs.11r01cr · Cited by 118

Audiovisual emotion recognition in schizophrenia: Reduced integration of facial and vocal affect

de Jong, J. J., Hodiamont, P. P. G., den Stock, J. V., & de Gelder, B. (2008) · Schizophrenia Research · doi:10.1016/j.schres.2008.10.001 · Cited by 123

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Shao, Z., Noh, H., Kim, W. B., Ni, P., Nguyen, C. L., Cote, S. E., Noyes, E. A., Zhao, J., Parsons, T. J., Park, J. M., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-018-0313-z · Cited by 113

Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice

Caldwell, H. K., Stephens, S. L., & Young, W. S. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002150 · Cited by 108

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Petrovsky, N., Ettinger, U., Hill, A., Frenzel, L., Meyhofer, I., Wagner, M., Backhaus, J., & Kumari, V. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0904-14.2014 · Cited by 102

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Swerdlow, N. R., Bhakta, S. G., Chou, H., Talledo, J., Balvaneda, B., & Light, G. A. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.162 · Cited by 102

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Crabtree, G. W., & Gogos, J. A. (2014) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2014.00028 · Cited by 106

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Dedic, N., Dworak, H., Zeni, C. M., Rutigliano, G., & Howes, O. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413185 · Cited by 104

The psychoses: Cluster 3 of the proposed meta-structure for DSM-V and ICD-11: Paper 4 of 7 of the thematic section: ‘A proposal for a meta-structure for DSM-V and ICD-11’

Carpenter, W. T., Bustillo, J. R., Thaker, G. K., van Os, J., Krueger, R. F., & Green, M. J. (2009) · Psychological Medicine · doi:10.1017/s0033291709990286 · Cited by 99

Advances in endophenotyping schizophrenia

BRAFF, D. L., Greenwood, T. A., Swerdlow, N. R., Light, G. A., & Schork, N. J. (2008) · World Psychiatry · doi:10.1002/j.2051-5545.2008.tb00140.x · Cited by 97

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Swerdlow, N. R., Light, G. A., Sprock, J., Calkins, M. E., Green, M. F., Greenwood, T. A., Gur, R. E., Gur, R. C., Lazzeroni, L. C., Nuechterlein, K. H., et al. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2013.12.004 · Cited by 97

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Braff, D. L., Light, G. A., & Swerdlow, N. R. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.08.015 · Cited by 90

Behavioural disturbances and altered Fos protein expression in adult rats after chronic pubertal cannabinoid treatment

Wegener, N., & Koch, M. (2008) · Brain Research · doi:10.1016/j.brainres.2008.11.081 · Cited by 90

Frontal–striatal–thalamic mediodorsal nucleus dysfunction in schizophrenia-spectrum patients during sensorimotor gating

Hazlett, E. A., Buchsbaum, M. S., Zhang, J., Newmark, R. E., Glanton, C. F., Zelmanova, Y., Haznedar, M. M., Chu, K.-W., Nenadić, I., Kemether, E. M., et al. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.05.039 · Cited by 90

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McGregor, C., Riordan, A. J., & Thornton, J. E. (2017) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2017.06.003 · Cited by 90

The Schizophrenia Risk Allele C of theTCF4rs9960767 Polymorphism Disrupts Sensorimotor Gating in Schizophrenia Spectrum and Healthy Volunteers

Quednow, B. B., Ettinger, U., Mößner, R., Rujescu, D., Giegling, I., Collier, D. A., Schmechtig, A., Kühn, K.-U., Möller, H., Maier, W., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0526-11.2011 · Cited by 83

Psychophysiological Methods and Developmental Psychopathology

Zisner, A. R., & Beauchaine, T. P. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy222 · Cited by 84

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Yang, P., Perlmutter, J. S., Benzinger, T. L. S., Morris, J. C., & Xu, J. (2019) · Ageing Research Reviews · doi:10.1016/j.arr.2019.100994 · Cited by 83

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Huang, L., Shum, E. Y., Jones, S. H., Lou, C.-H., Chousal, J. N., Kim, H. Y., Roberts, A. J., Jolly, L. A., Espinoza, J. L., Skarbrevik, D., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.173 · Cited by 79

S33138 (N-[4-[2-[(3 aS,9 bR)-8-cyano-1,3 a,4,9 b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3 H)-yl)-ethyl]phenyl-acetamide), a Preferential Dopamine D3 versus D2 Receptor Antagonist and Potential Antipsychotic Agent: III. Actions in Models of Therapeutic Activity and Induction of Side Effects

Millan, M. J., Loiseau, F., Dekeyne, A., Gobert, A., Flik, G., Cremers, T. I. F. H., Rivet, J., Sicard, D., Billiras, R., & Brocco, M. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.134536 · Cited by 79

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San-Martin, R., Castro, L. A., Menezes, P. R., Fraga, F. J., Simões, P. W. T. D. A., & Salum, C. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa059 · Cited by 78

The mouse attentional-set-shifting task: A method for assaying successful cognitive aging?

Young, J. W., Powell, S. B., Geyer, M. A., Jeste, D. V., & Risbrough, V. B. (2010) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/cabn.10.2.243 · Cited by 78

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Swerdlow, N. R. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.05.004 · Cited by 78

Sensorimotor Gating is Associated with CHRNA3 Polymorphisms in Schizophrenia and Healthy Volunteers

Petrovsky, N., Quednow, B. B., Ettinger, U., Schmechtig, A., Mößner, R., Collier, D. A., Kühn, K.-U., Maier, W., Wagner, M., & Kumari, V. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.12 · Cited by 77

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Wynn, J. K., Green, M. F., Sprock, J., Light, G. A., Widmark, C., Reist, C., Erhart, S. M., Marder, S. R., Mintz, J., & BRAFF, D. L. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.05.039 · Cited by 74

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Buse, J., Beste, C., Herrmann, E., & Roessner, V. (2015) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2015.1112033 · Cited by 73

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Light, G. A., Zhang, W., Joshi, Y. B., Bhakta, S. G., Talledo, J., & Swerdlow, N. R. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.81 · Cited by 73

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He, E., Gonzalez‐Lozano, M. A., Stringer, S., Watanabe, K., Sakamoto, K., den Oudsten, F., Koopmans, F., Giamberardino, S. N., Hammerschlag, A. R., Cornelisse, L. N., et al. (2018) · Human Molecular Genetics · doi:10.1093/hmg/ddy089 · Cited by 74

Prenatal immune challenge in rats: Effects of polyinosinic–polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine

Vorhees, C. V., Graham, D. L., Braun, A. A., Schaefer, T. L., Skelton, M. R., Richtand, N. M., & Williams, M. T. (2014) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2014.10.007 · Cited by 80

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Echeverrı́a, V. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00173 · Cited by 73

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Marsden, K. C., & Granato, M. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.10.060 · Cited by 72

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Levin, R. R., Calzavara, M. B., Santos, C. M., Medrano, W. A., Niigaki, S. T., & Abílio, V. C. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.06.003 · Cited by 71

Heritability of acoustic startle magnitude, prepulse inhibition, and startle latency in schizophrenia and control families

Hasenkamp, W. M., Epstein, M. P., Green, A. M., Wilcox, L., Boshoven, W., Lewison, B., & Duncan, E. (2010) · Psychiatry Research · doi:10.1016/j.psychres.2009.11.012 · Cited by 71

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Kumari, V., Antonova, E., & Geyer, M. A. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2007.11.006 · Cited by 70

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Roussos, P., Giakoumaki, S. G., & Bitsios, P. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.008 · Cited by 70

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Swerdlow, N. R. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.09.002 · Cited by 72

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Kumari, V., Fannon, D. G., Geyer, M. A., Premkumar, P., Antonova, E., Simmons, A., & Kuipers, E. (2008) · Cortex · doi:10.1016/j.cortex.2007.11.007 · Cited by 67

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Du, Y., Wu, X. H., & Li, L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1292-11.2011 · Cited by 66

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Savonenko, A., Muñoz, P., Melnikova, T., Wang, Q., Liang, X., Breyer, R., Montine, T., Kirkwood, A., & Andreasson, K. I. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.01.016 · Cited by 70

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Medan, V., & Preuss, T. (2014) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2014.07.006 · Cited by 66

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Zhou, X., Tang, W., Greenwood, T. A., Guo, S., He, L., Geyer, M. A., & Kelsoe, J. R. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005196 · Cited by 65

Brief subjective durations contract with repetition

Pariyadath, V., & Eagleman, D. M. (2008) · Journal of Vision · doi:10.1167/8.16.11 · Cited by 65

Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice

Ohira, K., Kobayashi, K., Toyama, K., Nakamura, H. K., Shoji, H., Takao, K., Takeuchi, R., Yamaguchi, S., Kataoka, M., Otsuka, S., et al. (2013) · Molecular Brain · doi:10.1186/1756-6606-6-12 · Cited by 60

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Swerdlow, N. R., Light, G. A., Thomas, M. L., Sprock, J., Calkins, M. E., Green, M. F., Greenwood, T. A., Gur, R. E., Gur, R. C., Lazzeroni, L. C., et al. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.05.013 · Cited by 65

Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex

Kuroiwa, M., Snyder, G. L., Shuto, T., Fukuda, A., Yanagawa, Y., Benavides, D. R., Nairn, A. C., Bibb, J. A., Greengard, P., & Nishi, A. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2436-8 · Cited by 64

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Hazlett, E. A., Romero, M. J., Haznedar, M. M., New, A. S., Goldstein, K. E., Newmark, R. E., Siever, L. J., & Buchsbaum, M. S. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.03.012 · Cited by 64

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Mohr, C., & Ettinger, U. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00184 · Cited by 63

Nicotine Effect on Prepulse Inhibition and Prepulse Facilitation in Schizophrenia Patients

Hong, L. E., Wonodi, I., Lewis, J., & Thaker, G. K. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301601 · Cited by 63

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