The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
The Structure of Genetic and Environmental Risk Factors for DSM-IV Personality Disorders: A Multivariate Twin Study
Open accessAbstract
CONTEXT: Although both genetic and environmental factors affect risk of individual personality disorders (PDs), we know little of how they contribute to the pattern of comorbidity between the PDs in the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) (DSM-IV). OBJECTIVE: To clarify the structure of the genetic and environmental risk factors for the 10 DSM-IV PDs. DESIGN: Assessment of PDs at personal interview and multivariate twin modeling with the Mx program. SETTING: General community. PARTICIPANTS: A total of 2794 young adult members of the Norwegian Institute of Public Health Twin Panel. Main Outcome Measure Number of endorsed criteria for the 10 DSM-IV PDs. RESULTS: The best-fit multivariate twin model required 3 genetic and 3 individual-specific environmental factors and genetic and individual-specific factors unique to each PD. The first genetic factor had high loadings on PDs from all 3 clusters including paranoid, histrionic, borderline, narcissistic, dependent, and obsessive-compulsive. The second genetic factor had substantial loadings only on borderline and antisocial PD. The third genetic factor had high loadings only on schizoid and avoidant PD. Several PDs had substantial disorder-specific genetic risk factors. The first, second, and third individual-specific environmental factors had high loadings on the cluster B, A, and C PDs, respectively, with 1 exception: obsessive-compulsive PD loaded with cluster B and not cluster C PDs. CONCLUSIONS: Genetic risk factors for DSM-IV PDs do not reflect the cluster A, B, and C typology. Rather, 1 genetic factor reflects a broad vulnerability to PD pathology and/or negative emotionality. The 2 other genetic factors are more specific and reflect high impulsivity/low agreeableness and introversion. Unexpectedly, the cluster A, B, and C typology is well reflected in the structure of environmental risk factors, suggesting that environmental experiences may be responsible for the tendency of cluster A, B, and C PDs to co-occur.
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Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. (2013) · Encyclopedia of Social Work · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,519
Akaike, H. (1987) · Springer Series in Statistics · doi:10.1007/978-1-4612-1694-0_29 · Cited by 4,027
Kendler, K. S., Prescott, C. A., Myers, J., & Neale, M. C. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.9.929 · Cited by 1,868
Self-citationDSM-IV Personality Disorders in the National Comorbidity Survey Replication
Lenzenweger, M. F., Lane, M. C., Loranger, A. W., & Kessler, R. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.019 · Cited by 1,352
The Prevalence of Personality Disorders in a Community Sample
Torgersen, S., Kringlen, E., & Cramer, V. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.6.590 · Cited by 1,313
Self-citationDelineating the Structure of Normal and Abnormal Personality: An Integrative Hierarchical Approach.
Markon, K. E., Krueger, R. F., & Watson, D. (2005) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.88.1.139 · Cited by 1,187
Genes, evolution, and personality
Bouchard, T. J., & Loehlin, J. C. (2001) · Behavior Genetics · doi:10.1023/a:1012294324713 · Cited by 1,085
The five-factor model and personality disorder empirical literature: A meta-analytic review
Saulsman, L. M., & Page, A. C. (2004) · Clinical Psychology Review · doi:10.1016/j.cpr.2002.09.001 · Cited by 915
Prevalence and correlates of personality disorder in Great Britain
Coid, J., Yang, M., Tyrer, P., Roberts, A., & Ullrich, S. (2006) · British Journal of Psychiatry · doi:10.1192/bjp.188.5.423 · Cited by 901
Widiger, T. A., & Samuel, D. B. (2005) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.114.4.494 · Cited by 752
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The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood
Lichtenstein, P., Carlström, E., Råstam, M., Gillberg, C., & Anckarsäter, H. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10020223 · Cited by 738
Miller, J. D., Dir, A., Gentile, B., Wilson, L., Pryor, L. R., & Campbell, W. K. (2010) · Journal of Personality · doi:10.1111/j.1467-6494.2010.00660.x · Cited by 530
Theory of mind and emotion regulation difficulties in adolescents with borderline traits
Sharp, C., Pane, H., Ha, C., Venta, A., Patel, A. B., Sturek, J., & Fonagy, P. (2011) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2011.01.017 · Cited by 492
Fineberg, N. A., Chamberlain, S. R., Goudriaan, A. E., Stein, D. J., Vanderschuren, L. J. M. J., Gillan, C. M., Shekar, S., Gorwood, P. A. P. M., Voon, V., Morein-Zamir, S., et al. (2014) · CNS Spectrums · doi:10.1017/s1092852913000801 · Cited by 488
Borderline personality disorder
Gunderson, J. G., Herpertz, S. C., Skodol, A. E., Torgersen, S., & Zanarini, M. C. (2018) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2018.29 · Cited by 470
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Metadata
- Authors
- Kendler, K. S., Aggen, S. H., Czajkowski, N., Røysamb, E., Tambs, K., Torgersen, S., Neale, M. C., & Reichborn-Kjennerud, T.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2008-12-01
- Volume
- 65
- Issue
- 12
- Pages
- 1438
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2053077346
- Cited by
- 278
- References
- 57
- FWCI
- 21.54
- Type
- journal article
- Language
- en
- Open access
- green
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