Cited by 172Bariatric Surgery and OutcomesBody Contouring and SurgeryMinimally Invasive Surgical Techniques

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Factors Associated With Weight Loss After Gastric Bypass

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Campos, Guilherme M.·2008·Archives of Surgery

DOI 10.1001/archsurg.143.9.877PMC PMC2747804

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Abstract

BACKGROUND: Gastric bypass (GBP) is the most common operation performed in the United States for morbid obesity. However, weight loss is poor in 10% to 15% of patients. We sought to determine the independent factors associated with poor weight loss after GBP. DESIGN: Prospective cohort study. We examined demographic, operative, and follow-up data by means of multivariate analysis. Variables investigated were age, sex, race, marital and insurance status, initial weight and body mass index (BMI) (calculated as weight in kilograms divided by height in meters squared), comorbidities (diabetes mellitus, hypertension, joint disease, sleep apnea, hyperlipidemia, and psychiatric disease), laparoscopic vs open surgery, gastric pouch area, gastrojejunostomy technique, and alimentary limb length. SETTING: University tertiary referral center. PATIENTS: All patients at our institution who underwent GBP from January 1, 2003, through July 30, 2006. MAIN OUTCOME MEASURES: Weight loss at 12 months defined as poor (< or =40% excess weight loss) or good (>40% excess weight loss). RESULTS: Follow-up data at 12 months were available for 310 of the 361 patients (85.9%) undergoing GBP during the study period. Mean preoperative BMI was 52 (range, 36-108). Mean BMI and excess weight loss at follow-up were 34 (range, 17-74) and 60% (range, 8%-117%), respectively. Thirty-eight patients (12.3%) had poor weight loss. Of the 4 variables associated with poor weight loss in the univariate analysis (greater initial weight, diabetes, open approach, and larger pouch size), only diabetes (odds ratio, 3.09; 95% confidence interval, 1.35-7.09 [P = .007]) and larger pouch size (odds ratio, 2.77;95% confidence interval, 1.81-4.22 [P <.001]) remained after the multivariate analysis. CONCLUSIONS: Gastric bypass results in substantial weight loss in most patients. Diabetes and larger pouch size are independently associated with poor weight loss after GBP.

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Authors: Campos, G. M.
Affiliations: University of California, San Francisco (US)
Corresponding author: Campos, Guilherme M.
ORCID: Campos, Guilherme M.
Venue: Archives of Surgery
Publisher: American Medical Association (AMA)
Published: 2008-09-15
Volume: 143
Issue: 9
Pages: 877
ISSN: 0004-0010 (ISSN-L)
DOI: 10.1001/archsurg.143.9.877
PMC: PMC2747804
OpenAlex: W1998092898
Cited by: 172
References: 63
Citations by year: 2026: 4 · 2025: 4 · 2024: 3 · 2023: 6 · 2022: 7 · 2021: 10 · 2020: 18 · 2019: 8 · 2018: 5 · 2017: 8 · 2016: 10 · 2015: 13 · 2014: 7 · 2013: 20 · 2012: 10
FWCI: 13.35
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Archives of Surgery (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: University of California, San Francisco
National Institute of Biomedical Imaging and Bioengineering (T32EB001631)
National Center for Research Resources (KL2RR024130)
Topics: Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
Health Sciences › Medicine › Surgery › Body Contouring and Surgery
Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
Keywords: gastric bypass, morbid obesity, weight loss, excess weight loss, diabetes mellitus, bariatric surgery outcomes
MeSH terms: Adult, Aged, Diabetes Mellitus, Female, Humans, Middle Aged, Obesity, Morbid, Postoperative Period, Gastric Bypass, Weight Loss, Comorbidity, Body Mass Index, Multivariate Analysis

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Factors Associated With Weight Loss After Gastric Bypass

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