The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Carotid Plaque Hemorrhage: Its Role in Production of Cerebral Ischemia
Abstract
A prospective study of carotid endarterectomy specimens showed an acute or recent intraplaque hemorrhage in 49 of 53 plaques (92.5%) from symptomatic patients, compared with seven of 26 plaques (27%) from nonsymptomatic patients. Luminal stenosis of greater than 50% was noted in 46 of 53 symptomatic patients (75%), 43 of whose plaques had evidence of multiple hemorrhages. Intimal disruption (ulceration) occurred over protruding mounds of intraplaque hemorrhage and was associated with retinal cholesterol emboli and prolonged neurologic deficits. Mural recesses with the angiographic appearance of ulceration seldom showed intimal breakdown. Eighteen patients continued to have symptoms while receiving aspirin, 13 of whom had had multiple intraplaque hemorrhages. Angioneogenesis occurred within the plaques in response to hemorrhage, creating vascular lesions vulnerable to mechanical stress and capable of producing further hemorrhage or intimal disruption.
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Citations
Cites
Controlled trial of aspirin in cerebral ischemia.
Fields, W. S., Lemak, N. A., Frankowski, R. F., & Hardy, R. J. (1977) · Stroke · doi:10.1161/01.str.8.3.301 · Cited by 631
Epidemiologic Assessment of the Role of Blood Pressure in Stroke: The Framingham Study
Kannel, W. B. (1970) · JAMA · doi:10.1001/jama.1970.03180020021004 · Cited by 2
Cited by
Moody, A. R., Murphy, R. E., Morgan, P. S., Martel, A. L., Delay, G. S., Allder, S., MacSweeney, S. T., Tennant, W. G., Gladman, J., Lowe, J., et al. (2003) · Circulation · doi:10.1161/01.cir.0000074222.61572.44 · Cited by 454
Hellings, W. E., Peeters, W., Moll, F. L., Piers, S. R. D., van Setten, J., Van der Spek, P. J., de Vries, J.-P. P. M., Seldenrijk, K. A., De Bruin, P. C., Vink, A., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.887497 · Cited by 447
Thickening of the Carotid Wall: A Marker for Atherosclerosis in the Elderly?
O’Leary, D. H., Polak, J. F., Kronmal, R. A., Savage, P. J., Borhani, N. O., Kittner, S. J., Tracy, R., Gardin, J. M., Price, T. R., & Furberg, C. D. (1996) · Stroke · doi:10.1161/01.str.27.2.224 · Cited by 381
Carotid plaque histology using real-time ultrasonography
Reilly, L. M., Lusby, R. J., Hughes, L., Ferrell, L. D., Stoney, R. J., & Ehrenfeld, W. K. (1983) · The American Journal of Surgery · doi:10.1016/0002-9610(83)90370-7 · Cited by 345
Self-citationSitzer, M., Müller, W., Siebler, M., Hort, W., Kniemeyer, H.-W., Jäncke, L., & Steinmetz, H. (1995) · Stroke · doi:10.1161/01.str.26.7.1231 · Cited by 340
Metadata
- Authors
- Lusby, R. J.
- Venue
- Archives of Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 1982-11-01
- Volume
- 117
- Issue
- 11
- Pages
- 1479
- ISSN
- 0004-0010 (ISSN-L)
- OpenAlex
- W1999778829
- Cited by
- 356
- References
- 2
- FWCI
- 13.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lusby, R. J. (1982). Carotid Plaque Hemorrhage: Its Role in Production of Cerebral Ischemia. Archives of Surgery. https://doi.org/10.1001/archsurg.1982.01380350069010
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
