The DOI matches its Crossref record; 93 of the 93 references it cites were found in a registry or an index.
Enhancing Recovery From Sepsis: A Review
Open accessAbstract
Importance: Survival from sepsis has improved in recent years, resulting in an increasing number of patients who have survived sepsis treatment. Current sepsis guidelines do not provide guidance on posthospital care or recovery. Observations: Each year, more than 19 million individuals develop sepsis, defined as a life-threatening acute organ dysfunction secondary to infection. Approximately 14 million survive to hospital discharge and their prognosis varies. Half of patients recover, one-third die during the following year, and one-sixth have severe persistent impairments. Impairments include development of an average of 1 to 2 new functional limitations (eg, inability to bathe or dress independently), a 3-fold increase in prevalence of moderate to severe cognitive impairment (from 6.1% before hospitalization to 16.7% after hospitalization), and a high prevalence of mental health problems, including anxiety (32% of patients who survive), depression (29%), or posttraumatic stress disorder (44%). About 40% of patients are rehospitalized within 90 days of discharge, often for conditions that are potentially treatable in the outpatient setting, such as infection (11.9%) and exacerbation of heart failure (5.5%). Compared with patients hospitalized for other diagnoses, those who survive sepsis (11.9%) are at increased risk of recurrent infection than matched patients (8.0%) matched patients (P < .001), acute renal failure (3.3% vs 1.2%, P < .001), and new cardiovascular events (adjusted hazard ratio [HR] range, 1.1-1.4). Reasons for deterioration of health after sepsis are multifactorial and include accelerated progression of preexisting chronic conditions, residual organ damage, and impaired immune function. Characteristics associated with complications after hospital discharge for sepsis treatment are not fully understood but include both poorer presepsis health status, characteristics of the acute septic episode (eg, severity of infection, host response to infection), and quality of hospital treatment (eg, timeliness of initial sepsis care, avoidance of treatment-related harms). Although there is a paucity of clinical trial evidence to support specific postdischarge rehabilitation treatment, experts recommend referral to physical therapy to improve exercise capacity, strength, and independent completion of activities of daily living. This recommendation is supported by an observational study involving 30 000 sepsis survivors that found that referral to rehabilitation within 90 days was associated with lower risk of 10-year mortality compared with propensity-matched controls (adjusted HR, 0.94; 95% CI, 0.92-0.97, P < .001). Conclusions and Relevance: In the months after hospital discharge for sepsis, management should focus on (1) identifying new physical, mental, and cognitive problems and referring for appropriate treatment, (2) reviewing and adjusting long-term medications, and (3) evaluating for treatable conditions that commonly result in hospitalization, such as infection, heart failure, renal failure, and aspiration. For patients with poor or declining health prior to sepsis who experience further deterioration after sepsis, it may be appropriate to focus on palliation of symptoms.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Around 15% develop one to two significant functional limitations, cognitive impairments, or mental health conditions”
From On race, human variation, and who gets and dies of sepsis (2022) · cites this paper as Prescott & Angus, 2018
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Nearly 60% of all people released from hospitals after sepsis are readmitted within the year. Approximately 40% die within 2 years, 80% within 5 years”
From On race, human variation, and who gets and dies of sepsis (2022) · cites this paper as Prescott & Angus, 2018
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Additionally, living in neighborhoods with low SES is associated with an increased risk of sepsis (575), community-acquired bacteremia (575) and death from bacteremia (576) and worse outcomes (577).”
From Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. (2021) · cites this paper as [577]
Experimental — accuracy not yet measuredIn the citing paper
“Almost 40% of sepsis survivors are re-hospitalised within 3 months, often for preventable conditions [580], contributing to increased healthcare costs [581].”
From Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) · cites this paper as [580]
In the citing paper
“In addition, sepsis survivors are at increased risk for recurrent infection, AKI and new cardiovascular events compared to patients hospitalised for other diagnoses [580].”
From Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) · cites this paper as [580]
In the citing paper
“There are a growing number of online resources and informational brochures regarding “post intensive care” / “post-sepsis syndrome”
From Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) · cites this paper as [580]
In the citing paper
“Nonetheless, based on their strong rationale, and benefit in related populations [580] (e.g., older patients with cognitive impairment, patients following stroke or traumatic brain injury), we suggest referral to rehabilitation programmes in survivors of sepsis.”
From Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) · cites this paper as [580]
In the citing paper
“Clinical studies have shown that the incidence of moderate-to-severe cognitive impairment in patients who survive severe sepsis is as high as 70% (Prescott & Angus, 2018).”
From The modulatory effects of gut microbes and metabolites on blood-brain barrier integrity and brain function in sepsis-associated encephalopathy (2023) · cites this paper as Prescott & Angus, 2018
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The third international consensus definitions for sepsis and septic shock (Sepsis-3).
Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J.-D., Coopersmith, C. M., et al. (2016) · JAMA · doi:10.1001/jama.2016.0287 · Cited by 28,250 · cited 2×
“CONCLUSIONS AND RELEVANCE In the months after hospital discharge for sepsis, management should focus on (1) identifying new physical, mental, and cognitive problems and referring for appropriate treatment, (2) reviewing and adjusting long-term medications, and (3) evaluating for treatable conditions that commonly resu…”
Self-citationAngus, D. C., Linde-Zwirble, W. T., Lidicker, J., Clermont, G., Carcillo, J., & Pinsky, M. R. (2001) · Critical Care Medicine · doi:10.1097/00003246-200107000-00002 · Cited by 8,503 · cited 1×
“The most common underlying infection is pneumonia (40%), followed by abdominal, genitourinary, primary bacteremia, and skin or soft tissue infections.(15,16)”
Self-citationSurviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4683-6 · Cited by 6,621 · cited 3×
“Early Hospital Treatment for Sepsis Early hospital care for sepsis focuses on prompt recognition, treatment with broad-spectrum antibiotics, elimination of infectious sources (eg, removing infected indwellingcatheters), and resuscitation with intravenous fluids and vasopressors for patients with low bloodpressureorele…”
InfluentialSelf-citationDiMatteo, M. R., Lepper, H. S., & Croghan, T. W. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.14.2101 · Cited by 4,177 · cited 1×
“However, it is important to recognize and treat mental health impairments because they are associated with a more complicated clinical course.(52,53)”
Severe Sepsis and Septic Shock
Angus, D. C., & van der Poll, T. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1208623 · Cited by 4,119
Self-citationBarr, J., Fraser, G. L., Puntillo, K., Ely, E. W., Gélinas, C., Dasta, J. F., Davidson, J. E., Devlin, J. W., Kress, J. P., Joffe, A. M., et al. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182783b72 · Cited by 3,896
Fleischmann, C., Scherag, A., Adhikari, N. K. J., Hartog, C. S., Tsaganos, T., Schlattmann, P., Angus, D. C., & Reinhart, K. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201504-0781oc · Cited by 3,548 · cited 2×
“CONCLUSIONS AND RELEVANCE In the months after hospital discharge for sepsis, management should focus on (1) identifying new physical, mental, and cognitive problems and referring for appropriate treatment, (2) reviewing and adjusting long-term medications, and (3) evaluating for treatable conditions that commonly resu…”
Self-citationSchweickert, W. D., Pohlman, M. C., Pohlman, A. S., Nigos, C., Pawlik, A. J., Esbrook, C. L., Spears, L., Miller, M., Franczyk, M., Deprizio, D., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60658-9 · Cited by 3,339
Wilson, I. B. (1995) · JAMA · doi:10.1001/jama.1995.03520250075037 · Cited by 3,027
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
Hotchkiss, R. S., Monneret, G., & Payen, D. (2013) · Nature Reviews Immunology · doi:10.1038/nri3552 · Cited by 2,772 · cited 1×
“Many patients continue to have inflammatory changes, immune suppression, or both after sepsis.(19)”
Cited by
Sorted by citations
Items 801–900 of 1,000
Fang, Y., XIA, F., Tian, F., QU, L., YANG, F., Fang, J., HU, Z., & LIU, H. (2024) · Biocell · doi:10.32604/biocell.2024.031539 · Cited by 1
Ma, H., Li, S., Dou, R., Lui, K. Y., Song, X., Qian, X., Liang, Y., Guan, X., & Cai, C. (2024) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2024.115790 · Cited by 1
Teixeira, C., & Rosa, R. G. (2024) · Critical Care Science · doi:10.62675/2965-2774.20240265-pt · Cited by 2
“A pressão econômica sobre os sistemas de saúde ao redor do mundo tem levado a uma busca incessante pela alta precoce das UTIs e dos hospitais.”
BackgroundPi, D., Zheng, L., Gao, C., Xiao, C., Yu, Z., Fu, Y.-Q., Li, J., Chen, C., Liu, C., Zou, Z., et al. (2024) · Shock · doi:10.1097/shk.0000000000002417 · Cited by 1
“Furthermore, survivors of sepsis often experience long-term physical, psychological, and cognitive impairments (7).”
SÍNDROME PÓS -CUIDADOS INTENSIVOS EM PACIENTES SÉPTICOS: REVISÃO SISTEMÁTICA
de Sousa, F. F., Reis, J. F. C., Alencar, A. J. F., de Andrade, E. N., Araújo, S. V. O., Silva, P. D. S., Sousa, G. H. M., Martins, N. N. S., de Freitas, A. V. F., & Lima, M. V. D. C. (2024) · Revista Contemporânea · doi:10.56083/rcv4n8-055 · Cited by 1
Lower leg cellulitis: A guide to diagnosis and management
Nazarko, L. (2024) · Independent Nurse · doi:10.12968/indn.2024.9.12 · Cited by 1
Fischer, J., Kohoutková, M. H., Frič, J., Šrámek, V., & Helán, M. (2025) · Anesteziologie a intenzivní medicína · doi:10.36290/aim.2024.064 · Cited by 1
García, B. A., López, A. P., Balado, Y. B., Lema, E. R., Marchán-López, Á., & Rey, R. R. (2025) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2025.107138 · Cited by 1
Sepsis and Septic Shock: A Review of Definitions, Pathogenesis, and Treatment
Butler, T., & Levin, J. (2019) · Springer eBooks · doi:10.1007/978-3-030-17148-3_22 · Cited by 1
Short- and Long-Term ICU-Acquired Immunosuppression
Grimaldi, D., & Pène, F. (2019) · Lessons from the ICU · doi:10.1007/978-3-030-24250-3_11 · Cited by 1
Persistent problems and recovery after critical illness
Mikkelsen, M. E., & Iwashyna, T. J. (2020) · doi:10.1093/med/9780198746690.003.0395 · Cited by 1
Aclaramiento del déficit de base estándar como pronóstico de mortalidad en choque séptico
Díaz, J. S. S., Gómez, G. G., Moguel, K. G. P., Zepeda, E. M., Rodríguez, E. A. M., & Sánchez, M. V. C. (2019) · Medicina Crítica · doi:10.35366/91599 · Cited by 1
“Ventilación mecánica, días (RI) 3 (1-5)* 4 (3-6)*”
Liu, Y., Yu, Y., Dai, H., & Fei, A. (2020) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2020.101172 · Cited by 1
“Worldwide, one-third of people who develop sepsis die ((5)).”
BackgroundSyndrome of persistent inflammation, the immune suppression and catabolism in surgery
Чуклін, С. М., Chuklin, S. S., & Shershen, G. (2020) · Klinicheskaia khirurgiia · doi:10.26779/2522-1396.2020.3-4.78 · Cited by 1
Chronic “sepsis brain” and regulatory T cells – A promising therapeutic target
Darden, D. B., Fenner, B. P., Foster, T. C., Larson, S. D., & Efron, P. A. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.01.017 · Cited by 1
“Up to 1/3 of patients with critical illness experience persistent anxiety sepsis survivors reported an increase in anxiety after discharge, which has a significant impact in quality of life (13).”
BackgroundCurrent Evidence on Coronavirus Disease-2019: A Comprehensive Review
Sharma, S., & Sood, M. (2021) · Pediatric Infectious Disease · doi:10.5005/jp-journals-10081-1286 · Cited by 1
Fasuyi, O. B., & Omole, F. S. (2022) · Springer eBooks · doi:10.1007/978-3-030-54441-6_45 · Cited by 1
Fleischmann-Struzek, C., Rose, N., Born, S., Freytag, A., Ditscheid, B., Storch, J., Schettler, A., Schlattmann, P., Wedekind, L., Pletz, M. W., et al. (2022) · neuroreha · doi:10.1055/a-1957-9382 · Cited by 1
“Als weite-re Ursachen werden Medikamentengaben und ein der post-trau-matischen Belastungsstörung ähnlicher Mechanismus als Folge in-tensivmedizinischer Therapien diskutiert [1].”
BackgroundInfluentialNi, J., Ding, Y., Miao, L., & Zhu, B. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm12010268 · Cited by 1
“Meanwhile, sepsis survivors were prone to mental health problems such as anxiety, depression, and post-traumatic stress disorder (PTSD), which will increase the mortality of patients [4].”
BackgroundGreenberg, J. A. (2020) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201912-889ed · Cited by 1
Introductory Chapter: Shock is a Physiological State of War
Stawicki, S. P., Papadimos, T. J., & Swaroop, M. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.88686 · Cited by 1
Press, A. T., Babic, P., Hoffmann, B., Müller, T., Foo, W., Hauswald, W., Benecke, J., Beretta, M., Cseresnyés, Z., Hoeppener, S., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.20.427305 · Cited by 1
Toward Tailored Care for Sepsis Survivors
Carlton, E. F. (2022) · Annals of the American Thoracic Society · doi:10.1513/annalsats.202203-240ed · Cited by 1
Fang, B., Wu, X., He, C., Xu, X. Z. S., Liu, C., Chen, C., Yang, H., Shi, H., Fei, Y., Sun, Y., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4074430 · Cited by 1
Life After Sepsis: The Journey Continues*
Scruth, E. A. (2023) · Critical Care Medicine · doi:10.1097/ccm.0000000000005970 · Cited by 1
Koami, H., Sakamoto, Y., Furukawa, Y., Mouri, K., Matsuoka, A., Shinada, K., Nakayama, K., Iwanaga, S., Narumi, S., & Koba, M. (2024) · medRxiv · doi:10.1101/2024.01.04.24300855 · Cited by 1
Denstaedt, S. J., McBean, B. N., Boyle, A. P., Arenberg, B. C., Mack, M., Moore, B. B., Newstead, M. W., Deng, Y., Nesvizhskii, A. I., Singer, B. H., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.16.654442 · Cited by 1
Self-citationThe Role of Physical Activity and Exercise in Acute Metabolic Perturbations to the Liver
Peppler, W. T. (2018) · The Atrium (University of Guelph)
Behavioral alterations are independent of previous generalized anxiety in experimental sepsis
Steckert, A. V., Michels, M., Ávila, P. R. M., Dominguini, D., Tomaz, D. B., Maisonnette, S. S., Barichello, T., Quevedo, J., Landeira-Fernández, J., & Dal‐Pizzol, F. (2018) · Neurology Psychiatry and Brain Research · doi:10.1016/j.npbr.2018.10.006
Identification of the adult septic patient in the prehospital and emergency department setting
Wallgren, U. M. (2019) · Figshare
Modalities for Physical Rehabilitation
Gosselink, R., Hollebeke, M. V., Clerckx, B., & Langer, D. (2019) · Lessons from the ICU · doi:10.1007/978-3-030-24250-3_19
Long-Lasting Memory Impairments after Subchronic Immune Challenge
Tchessalova, D. (2019) · Deep Blue (University of Michigan)
Are we getting any better at diagnosing sepsis?
Moss, S. R., & Prescott, H. C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-64068-8.00046-8
Self-citationMcSparron, J. I., & Iwashyna, T. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-64068-8.00013-4
Ben-nun-shaul, O., Srivastava, R., Elgavish, S., Gandhi, S., Nevo, Y., Benyamini, H., Eden, A., & Oppenheim, A. (2020) · OncoTarget · doi:10.18632/oncotarget.27448
SLPI and soluble BTLA as immunological markers in severe bacterial infections
Lange, A. (2020) · Diva portal (Dalarna University Library)
Heidner, R. L. (2019) · KU ScholarWorks (The University of Kansas)
Pimienta, G. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.08.285221
“Among patients with severe sepsis or septic shock, mortality 28 averages 25-30% [3] with many survivors experiencing long-term cognitive 29 impairment, residual organ damage and recurrent infections [4].”
BackgroundAguilera, J. C. G., Belizón, Y. E. V., Ortíz, A. A., & Lavernia, J. O. C. (2020) · DOAJ (DOAJ: Directory of Open Access Journals)
Effectiveness of Xuebijing injection for sepsis: an overview of systematic reviews and meta-analyses
Shi, Y.-L., Chen, C.-T., Yang, Y., Wang, Y., Chen, Y.-J., & Xu, Y. (2021) · Longhua Chinese Medicine · doi:10.21037/lcm-21-13
“Sepsis not only imposes a high burden on hospitalized patients (3), but also affects their quality of life, because half of the discharged patients are still not completely recovered (4,5).”
BackgroundEvaluation of the association between extravascular lung water and prognosis of sepsis
Luo, P., Song, C.-X., Ai, Y.-Q., Chen, Z., Yan, S.-N., Liu, X., Chen, Y., & Sun, J. (2021) · Medicine · doi:10.1097/md.0000000000023971
Guibla, I., Ilboudo, S., Bonkoungou, P., Traore, S., Yaro, I., Romba, B., & Traoré, I. (2021) · HEALTH SCIENCES AND DISEASE · doi:10.5281/hsd.v22i4.2663
Shao, Y., Zhang, W., Zhao, T., Lu, F., Hong, Y., Liu, L., Cai, Y., Wei, N., Cheng, H., Chen, F., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-73158/v2
Grebenchikov, O. A., & Kuzovlev, A. N. (2021) · Biochemistry (Moscow) · doi:10.31857/s0320972521050043
Sensing dengue and chikungunya virus (co-) infections
Briseño, A. A. (2021) · University of Groningen research database (University of Groningen / Centre for Information Technology) · doi:10.33612/diss.172910464
Circulating osteopontin released by injured kidneys causes pulmonary inflammation and edemaPreprint
Khamissi, F. Z., Ning, L., Kefaloyianni, E., Dun, H., Arthanarisami, A., Keller, A., Atkinson, J. J., Li, W., Wong, B. W., Dietmann, S., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.20.452998
Sepsis - an ED perspective. Sepsis Alert & Biomarkers.
Rosenqvist, M. (2021) · Lund University Publications (Lund University)
Lieutaud, S., & Vivet, A. (1984) · Francais dans le Monde
P-1-219 虫垂炎を初発症状として発症した盲腸癌手術例の検討(大腸炎症1,一般演題(ポスター),第64回日本消化器外科学会総会)
竹原, 清., 田中屋, 宏., 重安, 邦., 荒田, 尚., 村田, 宏., 金澤, 卓., 中川, 仁., 青木, 秀., & 竹内, 仁. (2009) · 日本消化器外科学会雑誌
Adaptive coscheduling for concurrent systems: Model and performance.
Lu, S., & Xie, L. (1998) · Computers and Their Applications
Fasuyi, O. B., & Omole, F. S. (2020) · Springer eBooks · doi:10.1007/978-1-4939-0779-3_45-2
Serrano, J. I. R. D. M., & Martinez, N. H. H. C. (2021) · American Journal of Medical and Clinical Sciences · doi:10.33425/2832-4226/21002
Zhang, B., Yin, S., Guo, C., Gao, Z., Li, T., Lee, W., Shen, J., & Yang, X. (2022) · Journal of Immunological Methods · doi:10.1016/j.jim.2022.113343
Taha, A. R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-88271-2.00007-9
Reducing sepsis-related unplanned 30-day readmissions at a hospital-based skilled nursing facility
Wang, Y., & Alvarado, I. (2023) · Journal of Nursing Education and Practice · doi:10.5430/jnep.v13n6p40
Li, Y., Chen, W., Guo, W., Wang, C., Li, S., & Chen, M. (2023) · Research Square · doi:10.21203/rs.3.rs-2756280/v1
(2023) · Elsevier eBooks · doi:10.1016/b978-3-437-23406-4.09983-8
Die Rolle der Pflege in der Erstversorgung septischer Patienten in der Notaufnahme
Zöller, J., Dormann, P., & Marohl, R. (2023) · Notfall + Rettungsmedizin · doi:10.1007/s10049-023-01173-6
Saturación venosa central: ¿marcador pronóstico en neumonía grave por SARS-CoV-2?
Pérez, N. I. R., Vera, J. E. B., Díaz, J. S. S., Moguel, K. G. P., Gaxiola, F. B., & Sánchez, M. V. C. (2023) · Medicina Crítica · doi:10.35366/112165
Wang, S., Dong, N., Tingting, X., Li, Y., & Xing, J. (2023) · Research Square · doi:10.21203/rs.3.rs-3286487/v1
Xu, W., Wu, Z., Jiang, Z., & Guo, T. (2023) · Research Square · doi:10.21203/rs.3.rs-3340668/v1
Zhou, J., Zhang, C., Liu, J., & Zhou, Y. (2023) · Research Square · doi:10.21203/rs.3.rs-3511763/v1
Jin, J. J., Zeng, M., Zhou, Q., & Yu, L. (2023) · Research Square · doi:10.21203/rs.3.rs-3565382/v1
Principles and Management of Sepsis
Edel, A., Fuest, K. E., & Karlis, G. (2023) · Lessons from the ICU · doi:10.1007/978-3-031-36398-6_1
Evaluation of innate lymphoid cells and long-term cognition in a rat model of experimental sepsisPreprint
Catalão, C. H. R., Petronilho, F. C., Dal‐Pizzol, F., Pillai, A., Giridharan, V. V., & Barichello, T. (2024) · Research Square · doi:10.21203/rs.3.rs-3829658/v1
REG1A may be a new biological marker for diagnosing sepsisPreprint
Li, Y., Guo, W., Chen, W., Wang, C., Li, S., Shen, Y., & Chen, M. (2024) · Research Square · doi:10.21203/rs.3.rs-3840154/v1
Persistent problems and recovery after critical illness
Mikkelsen, M. E., & Iwashyna, T. J. (2020) · doi:10.1093/med/9780198746690.003.0395_update_001
Zeng, T., Sun, Y., Chen, S., Pang, J., Wang, H., Cai, X., Liao, Y., Xiao, X., Zhang, Y., Chong, Y., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-3948492/v1
Fan, X., Li, Z., Gao, Y., Zhang, H.-S., & Bi, Z.-Y. (2024) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.40.5.8386
Therapeutic Effects of Ginsenoside Rh2 in the Treatment of Sepsis
Xiao, F., Peng, Z., Shen, F., Dun, S., & Chen, L. (2024) · Journal of Biobased Materials and Bioenergy · doi:10.1166/jbmb.2024.2447
Chen, Z., Zhang, W., Ye, H., Guo, Y.-Q., Zhang, K., & Fang, X. (2023) · Figshare · doi:10.6084/m9.figshare.22610198
Ellingjord‐Dale, M., Nygaard, A. B., Støer, N. C., Bø, R., Landrø, N. I., Brunvoll, S. H., Istre, M. S., Kalleberg, K. T., Dahl, J. A., Geng, L. N., et al. (2024) · medRxiv · doi:10.1101/2024.04.30.24306604
Evaluation of Factors Associated with Adult Sepsis Prognosis
Acar, C., Bozgül, Ş. M. K., & Bozkurt, D. (2024) · Namık Kemal Tıp Dergisi · doi:10.4274/nkmj.galenos.2024.59454
Yang, R., Hu, C., Zhuo, Y., Tan, Q., Shen, Y., Jiang, K., Xia, Q. J., & Deng, L. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4877717
Neurorehabilitation von Folgen nach einer Sepsis und Intensivbehandlung
Hamzei, F., & Seidel, G. (2024) · Springer eBooks · doi:10.1007/978-3-662-66957-0_37
Wassmuth, T., de Lara, E. M., Santos, E. B., Mazzo, D. M., Cerutti, D. M. L., PACHECO, M. Z., & Schleder, J. C. (2024) · Research Society and Development · doi:10.33448/rsd-v13i7.46276
Hosokawa, K., Kikutani, K., & Obata, Y. (2023) · THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA · doi:10.2199/jjsca.43.342
Sierpińska, L. E., Gawrońska, M., & Araminowicz-Kierklo, E. (2024) · American Journal of Health Behavior · doi:10.5993/ajhb.48.4.24
Nutritional support for sepsis: is there a single concept?
Пасечник, И. Н., Shchuchko, A. A., Kurochkin, M. S., & Новикова, Т. В. (2024) · Russian Journal of Anesthesiology and Reanimatology · doi:10.17116/anaesthesiology202406170
Increased quality of life indices among sepsis survivors rehabilitated in the RehaSep trial
Wójcik, B., Superata, J., Nguyen, H. B., Piwowar, M. W., & Szyguła, Z. (2024) · Bio-Algorithms and Med-Systems · doi:10.5604/01.3001.0054.9272
Ramos, J. G. R., Neto, M. J. D. S., Rezende, A. S., Ferreira, F. D. S., Amorim, Y. D. S., de Souza, F. R., & de Andrade, L. F. (2024) · Critical Care Science · doi:10.62675/2965-2774.20240015-pt
Sepse associada ao cateter venoso central na Unidade de Terapia Intensiva (UTI)
da Costa, B. B., Borgo, J. D. H., Tobias, D. F. D. S., Engel, N. D. A., Sobral, S. B., Baltar, L. M., da Silva, W. L., Said, M. B. D. C., de Andrade, E. D. S., da Silva, J. G., et al. (2025) · Caderno Pedagógico · doi:10.54033/cadpedv22n4-103
Jagesar, A. R., Smalbil, L., Galea, E., Dam, T. A., Hilders, P., Girbes, A. R. J., Thoral, P. J., Hoogendoorn, M., & Elbers, P. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5158206
Zuniga, E., & Makic, M. B. F. (2025) · Journal of PeriAnesthesia Nursing · doi:10.1016/j.jopan.2025.01.008
NET self-renewal: vascular Groundhog Day
Binley-Ewing, R., & Kubes, P. (2025) · Blood · doi:10.1182/blood.2024028067
Wagi, C. R., Kowalkowski, M. A., Taylor, S. P., Randazzo, A., Ganesan, A., Khanal, A., & Birken, S. A. (2025) · Implementation Science Communications · doi:10.1186/s43058-025-00743-8
Endothelial Control of the Inflammatory Process
Adam, A. P. (2025) · Springer eBooks · doi:10.1007/978-3-031-55254-0_9-1
Pulse pressure monitoring: A crucial bedside tool for nursing practice
Binda, F. (2025) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2025.104079
Structural and temporal dynamics analysis on PANoptosis in sepsis: a bibliometric analysisPreprint
Li, Z., Nie, D., Yin, L., Qin, Q., Yang, C., Li, R., Gao, X., Yu, X., & Wang, Y. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.02.657552
Nyesiga, S., Adégbitè, B. R., Haguma, P., Nsutebu, E. F., Rylance, J., & Jacob, S. T. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009052733.018
Sepsis Outcomes Worsened by Frailty: Findings from a National Inpatient SamplePreprint
Huang, W. Q., Yuan, Q., Dong, B., Zhang, J., Zhang, S., Liang, L., Liu, G., Wu, Y., Gao, Y., Yang, F., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-6677280/v1
Oliva, I. M. A. D. A., Ramos, J. G. R., Rezende, A. S., de Souza, F. R., & Martinez, B. P. (2025) · American Journal of Hospice and Palliative Medicine® · doi:10.1177/10499091251356593
Azhakath, A. S., Narayanan, V. P., Gopinathan, T., & Singh, V. P. (2025) · medRxiv · doi:10.1101/2025.07.07.25330923
Wang, X., Kong, F., Liu, Q., & Liu, X. (2025) · Biochemical Genetics · doi:10.1007/s10528-025-11198-w
Defining research priorities in sepsis: from protocols to personalisation
Aston, S., Todd, S., & French, N. (2025) · Anaesthesia · doi:10.1111/anae.16693
Sepsis Associated Encephalopathy: Pathology, Diagnosis and Therapeutic Interventions
Bandyopadhyay, D., & Mishra, D. (2024) · International Journal of Advanced Pharmaceutical Sciences and Research · doi:10.54105/ijapsr.e4086.04030424
Ge, Y., Li, M., Wang, B., Zhang, Y., Xiaoxian, Z. H. O. U., Zhang, Y., Li, T., Li, Y., Fang, S., & Liu, W. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5392487
García, B. A., López, A. P., Balado, Y. B., Lema, E. R., Marchán-López, Á., & Rey, R. R. (2025) · Medicina Clínica · doi:10.1016/j.medcli.2025.107138
Metadata
- Authors
- Prescott, H. C., & Angus, D. C.
- Affiliations
- University of Michigan (US)
- University of Pittsburgh (US)
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2018-01-02
- Volume
- 319
- Issue
- 1
- Pages
- 62
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC5839473
- OpenAlex
- W2782135811
- Semantic Scholar
- 98cad261fafa6b5df5332a165d01f11de1afd48e
- Cited by
- 1,059
- References
- 93
- Citations by year
- 2026: 143 · 2025: 149 · 2024: 161 · 2023: 142 · 2022: 124 · 2021: 135 · 2020: 103 · 2019: 67 · 2018: 32
- FWCI
- 65.73
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of General Medical Sciences (R01GM097471, K08GM115859)
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
- Keywords
- sepsis survivors, post-hospital care, post-discharge rehabilitation, physiotherapy referral, functional recovery, cognitive impairment, post-traumatic stress disorder, depression, anxiety, hospital readmission, recurrent infections, acute kidney injury, cardiovascular events, activities of daily living, sepsis severity, immune dysfunction, hospital quality of care, sepsis management guidelines
- MeSH terms
- Activities of Daily Living, Adult, Mental Disorders, Cognition Disorders, Hospitalization, Humans, Sepsis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
