Two-Year Survival Comparing Web-Based Symptom Monitoring vs Routine Surveillance Following Treatment for Lung Cancer
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This study reports 2-year survival outcomes among patients with advanced nonprogressive stage IIA to IV lung cancer randomized to symptom monitoring during chemotherapy via web-based patient-reported outcomes vs standard scheduled imaging after treatment to detect symptomatic recurrence.
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The SYMPRO-Lung study showed improved 2-year survival for patients with lung cancer monitored with web-based symptom tools.
“the SYMPRO-Lung study showed improved 2-year survival for patients with lung cancer monitored with web-based symptom tools [6].”
From Implementing UK Oncology Nursing Society–Informed Digital Symptom Triage With Episode-Based Review in Routine NHS Acute Oncology: Service Evaluation (2026) · cites this paper as [6]
The Results and Discussion in our copy (labeled Abstract; page unavailable) report improved survival after two years of web-based symptom monitoring for patients with lung cancer. The copy identifies the tool as the Sentinel PRO system but does not identify the trial as SYMPRO-Lung, so that study name is not supported. (LLM, conf=0.85)
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Cites
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“…trials have extended this evidence: the PRO-TECT trial demonstrated improved patient-reported outcomes across metastatic cancer types using electronic monitoring [5], and the SYMPRO-Lung study showed improved 2-year survival for patients with lung cancer monitored with web-based symptom tools [6].”
- Authors
- Denis, F., Basch, E., Septans, A.-L., Bennouna, J., Urban, T., Dueck, A. C., & Letellier, C.
- Affiliations
- Centre Jean Bernard (FR)
- University of North Carolina at Chapel Hill (US)
- Weprom, Angers, France
- Centre Hospitalier Universitaire de Nantes (FR)
- Centre Hospitalier Universitaire d'Angers (FR)
- Mayo Clinic in Arizona (US)
- Normandie Université–CORIA, Rouen, France
- Corresponding author
- Denis, Fabrice
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2019-01-22
- Volume
- 321
- Issue
- 3
- Pages
- 306
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC6439676
- OpenAlex
- W2914579361
- Cited by
- 549
- References
- 4
- Citations by year
- 2026: 53 · 2025: 76 · 2024: 59 · 2023: 70 · 2022: 106 · 2021: 96 · 2020: 68 · 2019: 21
- FWCI
- 30.36
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Eli Lilly and Company
- AstraZeneca
- National Cancer Institute
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Diagnosis and Treatment
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Keywords
- lung cancer, patient-reported outcomes, post-treatment surveillance, recurrence detection, two-year survival, chemotherapy
- MeSH terms
- Humans, Lung Neoplasms, Neoplasm Recurrence, Local, Population Surveillance, Internet, Kaplan-Meier Estimate, Self Report, Diagnostic Self Evaluation, Symptom Assessment
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