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Cited by 516

The DOI matches its OpenAlex record; 1 of the 1 references it cites were found in a registry or an index.

Chronic fatigue in primary care. Prevalence, patient characteristics, and outcome

Kurt Kroenke·1988·JAMA
DOI 10.1001/jama.260.7.929
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Abstract

Although fatigue is one of the most common complaints in ambulatory care, research has been minimal. Of the 1159 consecutive patients surveyed in two adult primary-care clinics, 276 (24%) indicated that fatigue was a major problem. Fatigue was more prevalent in women than in men (28% vs 19%). Extensive clinical, laboratory, psychometric, and functional data were gathered for 102 fatigued patients and 26 controls. Laboratory testing was not useful in detecting unsuspected medical conditions or in determining the cause of fatigue. Depression or somatic anxiety or both were suggested by screening psychometric instruments in 82 fatigued patients (80%) compared with three controls (12%). Global dysfunction was marked, as reported by patients on the Sickness Impact Profile. The mean score on the Sickness Impact Profile of 11.3 for fatigued patients is similar to that reported for patients with major medical illnesses. After one year of follow-up, only 29 fatigued patients (28%) had improved. The high prevalence, persistence, and functional consequences of fatigue mandate a search for effective therapy.

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Metadata

Authors
Kroenke, K.
Venue
JAMA
Publisher
American Medical Association
Published
1988-08-19
Volume
260
Issue
7
Pages
929-934
ISSN
0002-9955 (ISSN-L)
DOI
10.1001/jama.260.7.929
OpenAlex
W4235673608
Cited by
516
References
1
FWCI
15.76
Type
journal article
Language
en
Open access
closed

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