Burden of Disease—Implications for Future Research
Abstract
One overall challenge for public health and medicine in the future is to allocate available resources effectively to reduce major causes of disease burden globally and to decrease health disparities between poor and affluent populations. The major risk factors for death and disability worldwide are malnutrition; poor water supply, sanitation, and personal and domestic hygiene; unsafe sexual behavior; tobacco use; alcohol use; occupational hazards; hypertension; physical inactivity; illicit drugs; and air pollution. The challenge for research in the 21st century is to maintain and improve life expectancy and the quality of life that was achieved for most of the world's population during the 20th century.
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Both ischaemic heart disease and depression are among the top contributors to the disease burden worldwide in 2020.
“In 2020, IHD and depression are expected to be among the top contributors to the disease-burden worldwide.”
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- Authors
- Michaud, C. M.
- Affiliations
- Harvard University (US)
- Corresponding author
- Michaud, Catherine M.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2001-02-07
- Volume
- 285
- Issue
- 5
- Pages
- 535
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2034987992
- Cited by
- 594
- References
- 14
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 8 · 2023: 14 · 2022: 11 · 2021: 13 · 2020: 14 · 2019: 13 · 2018: 18 · 2017: 13 · 2016: 14 · 2015: 14 · 2014: 33 · 2013: 32 · 2012: 24
- FWCI
- 98.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Health Professions › Health Information Management › Global Health and Epidemiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Social Sciences › Business, Management and Accounting › Organizational Behavior and Human Resource Management › Global Public Health Policies and Epidemiology
- Keywords
- disease burden, global health, health disparities, malnutrition, water and sanitation, unprotected sex, tobacco use, alcohol consumption, occupational hazards, hypertension, physical inactivity, illicit drugs, air pollution, life expectancy, quality of life, resource allocation
- MeSH terms
- Humans, Life Expectancy, Public Health, Quality of Life, Research, Global Health, Cost of Illness
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