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Cited by 517Physical Activity and HealthObesity, Physical Activity, DietMenopause: Health Impacts and Treatments

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women: A Randomized Controlled Trial

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Irwin, Melinda L., Yasui, Yutaka, Ulrich, Cornelia M., Bowen, Deborah, Rudolph, Rebecca E., Schwartz, Robert S., Yukawa, Michi, Aiello, Erin, Potter, John D., McTiernan, Anne·2003·JAMA
DOI 10.1001/jama.289.3.323
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Abstract

CONTEXT: The increasing prevalence of obesity is a major public health concern. Physical activity may promote weight and body fat loss. OBJECTIVE: To examine the effects of exercise on total and intra-abdominal body fat overall and by level of exercise. DESIGN: Randomized controlled trial conducted from 1997 to 2001. SETTING AND PARTICIPANTS: A total of 173 sedentary, overweight (body mass index > or =24.0 and >33% body fat), postmenopausal women aged 50 to 75 years who were living in the Seattle, Wash, area. INTERVENTION: Participants were randomly assigned to an intervention consisting of exercise facility and home-based moderate-intensity exercise (n = 87) or a stretching control group (n = 86). MAIN OUTCOME MEASURE: Changes in body weight and waist and hip circumferences at 3 and 12 months; total body, intra-abdominal, and subcutaneous abdominal fat at 12 months. RESULTS: Twelve-month data were available for 168 women. Women in the exercise group participated in moderate-intensity sports/recreational activity for a mean (SD) of 3.5 (1.2) d/wk for 176 (91) min/wk. Walking was the most frequently reported activity. Exercisers showed statistically significant differences from controls in baseline to 12-month changes in body weight (-1.4 kg; 95% confidence interval [CI], -2.5 to -0.3 kg), total body fat (-1.0%; 95% CI, -1.6% to -0.4%), intra-abdominal fat (-8.6 g/cm2; 95% CI, -17.8 to 0.9 g/cm2), and subcutaneous abdominal fat (-28.8 g/cm2); 95% CI, -47.5 to -10.0 g/cm2). A significant dose response for greater body fat loss was observed with increasing duration of exercise. CONCLUSIONS: Regular exercise such as brisk walking results in reduced body weight and body fat among overweight and obese postmenopausal women.

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Metadata

Authors
Irwin, M. L., Yasui, Y., Ulrich, C. M., Bowen, D., Rudolph, R. E., Schwartz, R. S., Yukawa, M., Aiello, E., Potter, J. D., & McTiernan, A.
Affiliations
  • Yale University (US)
  • University of Washington (US)
Corresponding author
McTiernan, Anne
ORCID
Venue
JAMA
Publisher
American Medical Association (AMA)
Published
2003-01-15
Volume
289
Issue
3
Pages
323
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
DOI
10.1001/jama.289.3.323
OpenAlex
W2110141259
Cited by
517
References
35
Citations by year
2026: 4 · 2025: 5 · 2024: 7 · 2023: 12 · 2022: 12 · 2021: 16 · 2020: 17 · 2019: 8 · 2018: 16 · 2017: 15 · 2016: 26 · 2015: 19 · 2014: 24 · 2013: 29 · 2012: 28
FWCI
20.70
Type
journal article
Language
en
Open access
Locations
  • JAMA (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • U.S. Public Health Service (R01-69334)
  • National Institute on Aging (AG1094)
  • National Cancer Institute (T32 CA09661, T32CA009661)
  • National Center for Research Resources (M01-RR 00037, M01RR000037)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords
physical activity, postmenopausal women, intra-abdominal fat, total body fat, subcutaneous abdominal fat, obesity, overweight, weight loss, moderate-intensity exercise, home-based exercise, walking, waist circumference, dose-response relationship, sedentary women
MeSH terms
Abdomen, Adipose Tissue, Aged, Body Composition, Female, Humans, Middle Aged, Obesity, Weight Loss, Exercise, Body Mass Index, Postmenopause

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