Prevalence of female authors in case reports published in the medical literature
Open accessAbstract
Importance: Underrepresentation of female authors in research publications is prevalent, but it is unclear whether this is attributable to sex disparities in research conduct or authorship practices. Case reports are a poorly understood component of the biomedical corpus, and the production of anecdotal observations is not confounded by factors associated with disparities in female representation in research publications. Whether female authorship disparities exist in nonresearch publications of clinical information is unknown. Objectives: To examine the authorship of case reports and elucidate factors associated with sex disparity. Design and Setting: Cross-sectional study of all case reports published by US authors in 2014 and 2015 indexed in PubMed performed from July 2015 to July 2018. Main Outcomes and Measures: The primary outcome measure was the proportion of female first authors. The secondary outcome measures were the proportion of female last authors and female authorship representation among different clinical specialties. Results: Bibliometric data was abstracted from 20 427 case reports published across 2538 journals. A total of 7252 (36%) and 4825 (25%) case reports had a female first and last author, respectively. In comparison, 44% and 34% of US trainees and physicians, respectively, were female in 2015. Among adult case reports, female authorship was more prevalent in academic environments compared with community settings (34.0% vs 28.2% for female first authors and 23.4% vs 19.7% for female last authors). Across states, the proportions of female first authors and last authors were universally less than the proportions of female trainees and active female physicians, respectively. Female first authorship was associated with larger author teams (odds ratio [OR], 1.02; 95% CI, 1.01-1.03), an academic affiliation (OR, 1.16; 95% CI, 1.06-1.27), and a female last author (OR, 1.58; 95% CI, 1.47-1.70). Relative to general internal medicine, specialties dominated by male clinicians were less frequently associated with female first authors. Several exceptions displaying a relatively equivalent tendency for male and female first authorship included oncology (OR, 0.97; 95% CI, 0.81-1.16), ophthalmology (OR, 0.87; 95% CI, 0.72-1.05), and radiation oncology (OR, 0.94 95% CI, 0.56-1.56). Conclusions and Relevance: The underrepresentation of women among first and last authors in publications of case reports underscores the pervasiveness of sex disparities in medicine. Collaboration and female mentors may be critical instruments in upsetting longstanding practices associated with sex bias. Not all clinical specialties were associated with lower-than-expected female authorship, and further exploration of specialty-specific norms in publication and mentorship may elucidate specific barriers to female authorship.
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The minimum sample size to find associations was 844 studies, based on an error probability of 5%, power of 80%, equal proportion of exposed and unexposed, and estimated effect size OR=1.5.
“the minimum sample size to find associations, considering an error probability of 5% (α = 0.05), power (1-β) of 80%, an equal proportion of exposed and unexposed (women and men), and an estimated effect size of odds ratio (OR) = 1.5 based on a previous study of female team contribution 20 , was 844 studies.”
From Global mapping of randomized controlled trials in dentistry (2024) · cites this paper as [20]
A sample size calculation was performed, yielding a minimum sample size of 844 studies.
“The estimated minimum sample size to find associations, considering a probability of error of 5% (α = 0.05), power (1-β) of 80%, equal proportion of exposed and unexposed (women and men), and an estimated effect size of odds ratio (OR) = 1.5 based on a previous study on the contribution of female teams [23], was 844 studies.”
From Assessing transparency practices in dental randomized controlled trials (2024) · cites this paper as [23]
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Metaresearch study highlights the gender gap in randomized controlled trials in dentistry
Prado, M. C., Dotto, L., Agostini, B. A., & Sarkis-Onofre, R. (2023) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2023.08.005 · Cited by 10 · see citing works
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“…size to find associations, considering a probability of error of 5% (α = 0.05), power (1-β) of 80%, equal proportion of exposed and unexposed (women and men), and an estimated effect size of odds ratio (OR) = 1.5 based on a previous study on the contribution of female teams [23], was 844 studies.”
ResultInfluentialGlobal mapping of randomized controlled trials in dentistry
Prado, M. C., Dotto, L., Agostini, B., & Sarkis-Onofre, R. (2024) · Brazilian Dental Journal · doi:10.1590/0103-644020246233 · Cited by 1 · see citing works
- Authors
- Hsiehchen, D., Hsieh, A., & Espinoza, M.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- University of Pennsylvania (US)
- University of Arizona (US)
- Corresponding author
- Hsiehchen, David
- Venue
- JAMA Network Open
- Publisher
- American Medical Association (AMA)
- Published
- 2019-05-31
- Volume
- 2
- Issue
- 5
- Pages
- e195000
- ISSN
- 2574-3805 (ISSN-L)
- PMC
- PMC6547100
- OpenAlex
- W2947717634
- Cited by
- 23
- References
- 54
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 2 · 2022: 2 · 2021: 5 · 2020: 3 · 2019: 4
- FWCI
- 6.12
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- JAMA Network Open (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- UA Campus Repository (The University of Arizona) (acceptedVersion, cc-by)
- Topics
- Social Sciences › Gender Studies › Diversity and Career in Medicine
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › scientometrics and bibliometrics research
- Keywords
- female authorship, authorship practices, medical specialties, women in medicine, gender equity in research, bibliometric analysis, gender equity in science
- MeSH terms
- Adult, Authorship, Cross-Sectional Studies, Female, Humans, Middle Aged, Physicians, Women, Publications, Sex Factors, United States, Prevalence, Biomedical Research
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