The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Telomere Length Shortening and Alzheimer Disease—A Mendelian Randomization Study
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lele; 95% CI, 1.01 to 1
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“Supporting this idea, genetic variations in genes involved in telomere maintenance have been shown to correlate with AD susceptibility [121].”
From Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology (2023) · cites this paper as [121]
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Cites
Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease
(EADI), E. A. D. I., Lambert, J.-C., (GERAD), G. A. E. R. I. A. D., Alzheimer's Disease Genetic Consortium (ADGC), (CHARGE), C. F. H. A. A. R. I. G. E., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., et al. (2013) · Nature Genetics · doi:10.1038/ng.2802 · Cited by 4,336
EPIC- InterAct Consortium, Burgess, S., Scott, R. A., Timpson, N. J., Davey Smith, G., & Thompson, S. G. (2015) · European Journal of Epidemiology · doi:10.1007/s10654-015-0011-z · Cited by 1,803
Telomeres and human disease: ageing, cancer and beyond
Blasco, M. A. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1656 · Cited by 1,434
Identification of seven loci affecting mean telomere length and their association with disease
CARDIoGRAM consortium, Codd, V., Nelson, C. P., Albrecht, E., Mangino, M., Deelen, J., Buxton, J. L., Hottenga, J. J., Fischer, K., Esko, T., et al. (2013) · Nature Genetics · doi:10.1038/ng.2528 · Cited by 933
Self-citationThe Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., et al. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001474 · Cited by 203
Self-citationAssociation of Shorter Leukocyte Telomere Repeat Length With Dementia and Mortality
Honig, L. S., Kang, M. S., Schupf, N., Lee, J. H., & Mayeux, R. P. (2012) · Archives of Neurology · doi:10.1001/archneurol.2012.1541 · Cited by 179
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Items 101–110 of 110
Telomeres in Germ Line and Early Embryo: An Overview
Fernández, J. L., & González-Vasconcellos, I. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812571-7.00006-x · Cited by 1
Epigenetics, aging and early life
Dhingra, R., Nwanaji‐Enwerem, J. C., Aiello, A. E., Sentilles, F., King, B. G., & Ward-Caviness, C. K. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819968-8.00011-1 · Cited by 2
Liu, R., Xiang, M., Pilling, L. C., Melzer, D. R., Wang, L., Manning, K. J., Steffens, D. C., Bowden, J., Fortinsky, R. H., Kuchel, G. A., et al. (2022) · medRxiv · doi:10.1101/2022.06.30.22277121 · Cited by 1
“While previous MR studies reported a protective effect of genetically determined longer TL on AD risk [38,39], we did not find significant genetic associations with AD/ADRD or its subtypes in our MR analyses.”
ResultBayón, A. R., & Sampedro, F. G. (2017) · Neurología · doi:10.1016/j.nrl.2017.01.010
Editorial: Telomeres and Epigenetics in Endocrinology
Zhan, Y., & Song, H. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00257
Self-citationTelomere Length Alterations Associated with Breast, Thyroid and Cervical Cancers
Singh, Z., & Khangotra, P. (2019) · Journal of Health Science Research · doi:10.18311/jhsr/0/23361
Telomere length and cognitive changes in 7,877 older UK adults of European ancestry
Packer, A. E., Habiballa, L., Tato, E., Breen, G. D., Brooker, H. J., Corbett, A., Arathimos, R., Ballard, C. G., Hampshire, A., Palmer, A., et al. (2024) · Frontiers in Aging · doi:10.3389/fragi.2024.1480326
Wang, Q., Liu, F., Cai, B., Wang, X., Deng, Y., & Chen, T. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04913-6
“Several prior MR studies have also shown an association between TL and the risk of AD [11, 15, 16].”
InfluentialZhang, X., Xu, Y., Wang, S., Seth, I., Huang, Y. S., Zhang, X., Du, Z., Zhuang, D., Liu, S., Hu, Y., et al. (2025) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.70117
“%) with VD.”
Metadata
- Authors
- Zhan, Y., Song, C., Karlsson, R., Tillander, A., Reynolds, C. A., Pedersen, N. L., & Hägg, S.
- Affiliations
- Karolinska Institutet (SE)
- University of California, Riverside (US)
- Corresponding author
- Hägg, Sara
- ORCID
- Venue
- JAMA Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 2015-10-01
- Volume
- 72
- Issue
- 10
- Pages
- 1202
- ISSN
- 2168-6149 (ISSN-L)
- OpenAlex
- W2122450728
- Cited by
- 111
- References
- 6
- Citations by year
- 2025: 7 · 2024: 4 · 2023: 8 · 2022: 6 · 2021: 9 · 2020: 18 · 2019: 18 · 2018: 23 · 2017: 10 · 2016: 7 · 2015: 1
- FWCI
- 11.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- telomere length, telomere shortening, Alzheimer's disease, genetic variants, causal inference
- MeSH terms
- Alzheimer Disease, Genetic Testing, Humans, Risk, Telomere, Polymorphism, Single Nucleotide, Mendelian Randomization Analysis
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