The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Telomere Length Shortening and Alzheimer Disease—A Mendelian Randomization Study
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lele; 95% CI, 1.01 to 1
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“Supporting this idea, genetic variations in genes involved in telomere maintenance have been shown to correlate with AD susceptibility [121].”
From Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology (2023) · cites this paper as [121]
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Cites
Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease
(EADI), E. A. D. I., Lambert, J.-C., (GERAD), G. A. E. R. I. A. D., Alzheimer's Disease Genetic Consortium (ADGC), (CHARGE), C. F. H. A. A. R. I. G. E., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., et al. (2013) · Nature Genetics · doi:10.1038/ng.2802 · Cited by 4,336
EPIC- InterAct Consortium, Burgess, S., Scott, R. A., Timpson, N. J., Davey Smith, G., & Thompson, S. G. (2015) · European Journal of Epidemiology · doi:10.1007/s10654-015-0011-z · Cited by 1,803
Telomeres and human disease: ageing, cancer and beyond
Blasco, M. A. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1656 · Cited by 1,434
Identification of seven loci affecting mean telomere length and their association with disease
CARDIoGRAM consortium, Codd, V., Nelson, C. P., Albrecht, E., Mangino, M., Deelen, J., Buxton, J. L., Hottenga, J. J., Fischer, K., Esko, T., et al. (2013) · Nature Genetics · doi:10.1038/ng.2528 · Cited by 933
Self-citationThe Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., et al. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001474 · Cited by 203
Self-citationAssociation of Shorter Leukocyte Telomere Repeat Length With Dementia and Mortality
Honig, L. S., Kang, M. S., Schupf, N., Lee, J. H., & Mayeux, R. P. (2012) · Archives of Neurology · doi:10.1001/archneurol.2012.1541 · Cited by 179
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Blackburn, E. H., Epel, E. S., & Lin, J. (2015) · Science · doi:10.1126/science.aab3389 · Cited by 1,596
Jylhävä, J., Pedersen, N. L., & Hägg, S. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.03.046 · Cited by 1,240
“Likewise, in ADpatients, telomere lengths have been shown to be shorter, both in observational (Forero et al., 2016a) and causal Mendelian Randomization (Zhan et al., 2015) studies.”
BackgroundSelf-citationTelomere Length and All-Cause Mortality: A Meta-analysis
Wang, Q., Zhan, Y., Pedersen, N. L., Fang, F., & Hägg, S. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.09.002 · Cited by 333
Self-citationMeta-analysis of Telomere Length in Alzheimer’s Disease
Forero, D. A., González-Giraldo, Y., López-Quintero, C., Castro-Vega, L. J., Barreto, G. E., & Perry, G. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glw053 · Cited by 229
“Future studies using high-throughput approaches, such as nextgeneration sequencing, could identify novel genetic and epigenetic factors (39) that influence TL in AD patients and in its presymptomatic stages (40).”
BackgroundPuterman, E., Gemmill, A., Karasek, D., Weir, D., Adler, N. E., Prather, A. A., & Epel, E. S. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1525602113 · Cited by 165
“They showed that common sequence variants of seven genes that directly regulate telomere maintenance, summed as a genetic risk score, significantly increase risks for cardiovascular, pulmonary (23), and Alzheimer’s diseases (24).”
Background
Metadata
- Authors
- Zhan, Y., Song, C., Karlsson, R., Tillander, A., Reynolds, C. A., Pedersen, N. L., & Hägg, S.
- Affiliations
- Karolinska Institutet (SE)
- University of California, Riverside (US)
- Corresponding author
- Hägg, Sara
- ORCID
- Venue
- JAMA Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 2015-10-01
- Volume
- 72
- Issue
- 10
- Pages
- 1202
- ISSN
- 2168-6149 (ISSN-L)
- OpenAlex
- W2122450728
- Cited by
- 111
- References
- 6
- Citations by year
- 2025: 7 · 2024: 4 · 2023: 8 · 2022: 6 · 2021: 9 · 2020: 18 · 2019: 18 · 2018: 23 · 2017: 10 · 2016: 7 · 2015: 1
- FWCI
- 11.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- telomere length, telomere shortening, Alzheimer's disease, genetic variants, causal inference
- MeSH terms
- Alzheimer Disease, Genetic Testing, Humans, Risk, Telomere, Polymorphism, Single Nucleotide, Mendelian Randomization Analysis
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