Cited by 826Schizophrenia research and treatmentPsychiatric care and mental health servicesMental Health Treatment and Access

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Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression

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Correll, Christoph U., Galling, Britta, Pawar, Aditya, Krivko, Anastasia, Bonetto, Chiara, Ruggeri, Mirella, Craig, Thomas J., Nordentoft, Merete, Srihari, Vinod H., Guloksuz, Sinan, Hui, Christy L. M., Chen, Eric Y. H., Valencia, Marcelo, Juarez, Francisco, Robinson, Delbert G., Schooler, Nina R., Brunette, Mary F., Mueser, Kim T., Rosenheck, Robert A., Marcy, Patricia, Addington, Jean, Estroff, Sue E., Robinson, James, Penn, David, Severe, Joanne B., Kane, John M.·2018·JAMA Psychiatry

DOI 10.1001/jamapsychiatry.2018.0623PMC PMC6137532

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Abstract

Importance: The value of early intervention in psychosis and allocation of public resources has long been debated because outcomes in people with schizophrenia spectrum disorders have remained suboptimal. Objective: To compare early intervention services (EIS) with treatment as usual (TAU) for early-phase psychosis. Data Sources: Systematic literature search of PubMed, PsycINFO, EMBASE, and ClinicalTrials.gov without language restrictions through June 6, 2017. Study Selection: Randomized trials comparing EIS vs TAU in first-episode psychosis or early-phase schizophrenia spectrum disorders. Data Extraction and Synthesis: This systematic review was conducted according to PRISMA guidelines. Three independent investigators extracted data for a random-effects meta-analysis and prespecified subgroup and meta-regression analyses. Main Outcomes and Measures: The coprimary outcomes were all-cause treatment discontinuation and at least 1 psychiatric hospitalization during the treatment period. Results: Across 10 randomized clinical trials (mean [SD] trial duration, 16.2 [7.4] months; range, 9-24 months) among 2176 patients (mean [SD] age, 27.5 [4.6] years; 1355 [62.3%] male), EIS was associated with better outcomes than TAU at the end of treatment for all 13 meta-analyzable outcomes. These outcomes included the following: all-cause treatment discontinuation (risk ratio [RR], 0.70; 95% CI, 0.61-0.80; P < .001), at least 1 psychiatric hospitalization (RR, 0.74; 95% CI, 0.61-0.90; P = .003), involvement in school or work (RR, 1.13; 95% CI, 1.03-1.24; P = .01), total symptom severity (standardized mean difference [SMD], -0.32; 95% CI, -0.47 to -0.17; P < .001), positive symptom severity (SMD, -0.22; 95% CI, -0.32 to -0.11; P < .001), and negative symptom severity (SMD, -0.28; 95% CI, -0.42 to -0.14; P < .001). Superiority of EIS regarding all outcomes was evident at 6, 9 to 12, and 18 to 24 months of treatment (except for general symptom severity and depressive symptom severity at 18-24 months). Conclusions and Relevance: In early-phase psychosis, EIS are superior to TAU across all meta-analyzable outcomes. These results support the need for funding and use of EIS in patients with early-phase psychosis.

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Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
Higgins, J. P. T., Altman, D. G., Gotzsche, P. C., Juni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., Sterne, J. A. C., et al. (2011) · BMJ · doi:10.1136/bmj.d5928 · Cited by 33,817
A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants
Dermyshi, E., Wang, Y., Yan, C., Hong, W., Qiu, G., Gong, X., & Zhang, T. (2017) · Neonatology · doi:10.1159/000454668 · Cited by 24,586
Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>
Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623
The Effect of Riding as an Alternative Treatment for Children with Cerebral Palsy: A Systematic Review and Meta-Analysis
Wang, G., Ma, R., Qiao, G., Wada, K., Aizawa, Y., & Satoh, T. (2015) · Integrative Medicine International · doi:10.1159/000368408 · Cited by 18,762

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Birchwood, 2014, The UK national evaluation of the development and impact of Early Intervention Services (the National EDEN studies): study rationale, design and baseline characteristics., Early Interv Psychiatry, 8, 59, 10.1111/eip.2014.8.issue-1 · DOI
Hui, 2015, Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study., Early Interv Psychiatry, 9, 118, 10.1111/eip.2015.9.issue-2 · DOI

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Myers, N., Hutnyan, M., Daley, T. C., Bello, I., Chacon, M., Currie, A., Davis, B. J., Dixon, L. B., George, P., Giannicchi, A., et al. (2023) · Psychiatric Services · doi:10.1176/appi.ps.20220121 · Cited by 12
Schizophrenia spectrum disorders in Denmark between 2000 and 2018: Incidence and early diagnostic transition
Köhler‐Forsberg, O., Antonsen, S., Pedersen, C. B., Mortensen, P. B., McGrath, J. J., & Mors, O. N. (2023) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13565 · Cited by 12
Post‐secondary students with symptoms of psychosis: A mixed‐methods systematic review
Sanderson, V., Vandyk, A. D., Graham, I. D., Lightfoot, S., Murawsky, M., Sikora, L., & Jacob, J. D. (2020) · International Journal of Mental Health Nursing · doi:10.1111/inm.12700 · Cited by 13
How does reorganisation in child and adolescent mental health services affect access to services? An observational study of two services in England
Fazel, M. S., Rocks, S., Głogowska, M., Stepney, M., & Tsiachristas, A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250691 · Cited by 12
Classification of first-episode psychosis using cortical thickness: A large multicenter MRI study
Pigoni, A., Dwyer, D., Squarcina, L., Borgwardt, S., Crespo‐Facorro, B., Dazzan, P., Smesny, S., Španiel, F., Spalletta, G., Sanfelici, R., et al. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.04.002 · Cited by 13
Self-citation
Psychosis Early Intervention Across the Life Span: A Service Perspective
Taylor, K. M., Orucu, E., Nandha, S., & Cella, M. (2022) · Community Mental Health Journal · doi:10.1007/s10597-022-01004-x · Cited by 12
The benefit of foresight? An ethical evaluation of predictive testing for psychosis in clinical practice
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Putting measurement-based care into action: a multi-method study of the benefits of integrating routine client feedback in coordinated specialty care programs for early psychosis
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A protocol for the first episode psychosis outcome study ( FEPOS ): ≥15 year follow‐up after treatment at the Early Psychosis Prevention and Intervention Centre, Melbourne, Australia
Cotton, S., Filia, K., Watson, A., Mackinnon, A. J., Hides, L. M., Gleeson, J., Berk, M., Conus, P., Lambert, M., SCHIMMELMANN, B. G., et al. (2021) · Early Intervention in Psychiatry · doi:10.1111/eip.13204 · Cited by 11
Outcomes for first-episode psychosis after entry via an at-risk mental state clinic compared to direct entry to a first episode of psychosis service: A systematic review and meta-analysis
Sizer, H., Brown, E., Geros, H., Yung, A. R., Nelson, B., McGorry, P. D., & O'Donoghue, B. N. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2021.12.019 · Cited by 11
Specialized inpatient treatment for young people with early psychosis: acute-treatment and 12-month results
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Relationship between patterns of cannabis use and functional and symptomatic trajectories in first-episode psychosis
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Self-citation
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Self-citation
Discharge destinations for young people with a first episode of psychosis after attending an early intervention for psychosis service
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Self-citation
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Self-citation
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Self-citation
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Self-citation
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Self-citation
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Self-citation
[Validation of a French version of the 16-item Prodromal Questionnaire (fPQ16) in adolescents and young adults seeking help].
Lejuste, F., Pedron, L., Bonnard, E., Urban, M., Morvan, Y., Urben, S., Gaillard, R., Conus, P., & Krebs, M. (2021) · L'Encephale · doi:10.1016/j.encep.2020.11.009 · Cited by 9
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Interventions for people at ultra‐high risk for psychosis: A systematic review of economic evaluations
Ologundudu, O. M., Lau, T., Palaniyappan, L., Ali, S., & Anderson, K. K. (2021) · Early Intervention in Psychiatry · doi:10.1111/eip.13061 · Cited by 10
Community indicators for mental health in Europe: a scoping review
Schoenweger, P., Kirschneck, M., Biersack, K., Meo, A.-F. J. D., Reindl-Spanner, P., Prommegger, B., Ditzen-Janotta, C., Henningsen, P., Krcmar, H., Gensichen, J. S., et al. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1188494 · Cited by 9
Care Pathways and Initial Engagement in Early Psychosis Intervention Services Among Youths and Young Adults
Polillo, A., Foussias, G., Wang, W., Voineskos, A. N., Veras, J., Davis-Faroque, N., Wong, A. H. C., & Kozloff, N. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.33526 · Cited by 10

Authors: Correll, C. U., Galling, B., Pawar, A., Krivko, A., Bonetto, C., Ruggeri, M., Craig, T. J., Nordentoft, M., Srihari, V. H., Guloksuz, S., Hui, C. L. M., Chen, E. Y. H., Valencia, M., Juarez, F., Robinson, D. G., Schooler, N. R., Brunette, M. F., Mueser, K. T., Rosenheck, R. A., Marcy, P., Addington, J., Estroff, S. E., Robinson, J., Penn, D., Severe, J. B., & Kane, J. M.
Affiliations: Northwell Health (US)
University of Verona (IT)
Institute of Psychiatry, King’s College London, London, England
Copenhagen University Hospital (DK)
Yale University (US)
Department of Psychiatry, Yale University, New Haven, Connecticut
University of Hong Kong (HK)
Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (MX)
Division of Epidemiological and Psychosocial Research, National Institute of Psychiatry, Mexico City, Mexico
Dartmouth College (US)
Boston University (US)
University of Calgary (CA)
University of North Carolina at Chapel Hill (US)
Nathan Kline Institute for Psychiatric Research (US)
National Institute of Mental Health (US)
Corresponding author: Correll, Christoph U.
ORCID: Correll, Christoph U.
Galling, Britta
Pawar, Aditya
Bonetto, Chiara
Ruggeri, Mirella
Nordentoft, Merete
Srihari, Vinod H.
Hui, Christy L. M.
Chen, Eric Y. H.
Robinson, Delbert G.
Schooler, Nina R.
Brunette, Mary F.
Mueser, Kim T.
Rosenheck, Robert A.
Marcy, Patricia
Addington, Jean
Penn, David
Kane, John M.
Venue: JAMA Psychiatry
Publisher: American Medical Association (AMA)
Published: 2018-06-01
Volume: 75
Issue: 6
Pages: 555
ISSN: 2168-622X (ISSN-L)
DOI: 10.1001/jamapsychiatry.2018.0623
PMC: PMC6137532
OpenAlex: W2799778639
Cited by: 826
References: 66
Citations by year: 2026: 106 · 2025: 110 · 2024: 115 · 2023: 96 · 2022: 118 · 2021: 105 · 2020: 95 · 2019: 68 · 2018: 13
FWCI: 55.28
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: JAMA Psychiatry (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
Research Publications (Maastricht University) (submittedVersion, other-oa)
Funders: Patrick and Catherine Weldon Donaghue Medical Research Foundation
Bristol-Myers Squibb
Eli Lilly and Company
Sanofi
American Academy of Child and Adolescent Psychiatry
Sunovion
Wellcome Trust
National Institute for Health and Care Research
Lundbeckfonden (R155-2014-1724, R248‐2017‐2003)
Novo Nordisk
Allergan
National Institute of Mental Health (RC1MH088971, P30MH090590)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords: early intervention services, first-episode psychosis, schizophrenia spectrum disorders, usual care, treatment discontinuation, psychiatric hospitalization, symptom severity, social functioning, public resource allocation, mental health services, randomized trial comparison, treatment duration
MeSH terms: Education, Employment, Hospitalization, Humans, Psychotic Disorders, Regression Analysis, Schizophrenia, Schizophrenic Psychology, Severity of Illness Index, Randomized Controlled Trials as Topic, Early Medical Intervention

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Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression

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