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Efficacy and Safety of Ursodeoxycholic Acid for the Prevention of Gallstone Formation After Gastrectomy in Patients With Gastric Cancer: The PEGASUS-D Randomized Clinical Trial

Lee, Sang Hyub, Jang, Dong Kee, Yoo, Moon-Won, Hwang, Sun-Hwi, Ryu, Seong-Yeob, Kwon, Oh Kyoung, Hur, Hoon, Man Yoon, Hong, Eom, Bang Wool, Ahn, Hye Seong, Son, Taeil, Song, Kyo Young, Lee, Han Hong, Choi, Min-Gew, An, Ji Yeong, Lee, Sang-Il, Lee, Kyung Ho, Ahn, Soyeon, Park, Young Suk, Park, Do Joong, for the Efficacy and Safety of DWJ1319 in the Prevention of Gallstone Formation after Gastrectomy in Patient with Gastric Cancer: A Multicenter, Randomized, Double-blind, Placebo-controlled Study (PEGASUS-D) Group·2020·JAMA Surgery
DOI 10.1001/jamasurg.2020.1501PMC PMC7301302
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Figure 1. Flow of Patient Enrollment, Randomization, and Follow-up FAS indicates full analysis set; PPS, per-protocol set, and UDCA, ursodeoxycholic acid.
Figure 1. Flow of Patient Enrollment, Randomization, and Follow-up FAS indicates full analysis set; PPS, per-protocol set, and UDCA, ursodeoxycholic acid.CC BY-NC-ND · PubMed Central
Figure 2. Cumulative Probability of Gallstone Formation According to Ursodeoxycholic Acid (UDCA) Dosage (Full Analysis Set) Tic marks indicate censored data.
Figure 2. Cumulative Probability of Gallstone Formation According to Ursodeoxycholic Acid (UDCA) Dosage (Full Analysis Set) Tic marks indicate censored data.CC BY-NC-ND · PubMed Central

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Research works printed but not linked: 41

  1. Park, 2016, Risk factors for gallstone formation after surgery for gastric cancer., J Gastric Cancer, 16, 98, 10.5230/jgc.2016.16.2.98 · DOI
  2. Fukagawa, 2009, Gallstone formation after gastric cancer surgery., J Gastrointest Surg, 13, 886, 10.1007/s11605-009-0832-8 · DOI
  3. Kimura, 2017, Is routine prophylactic cholecystectomy necessary during gastrectomy for gastric cancer?, World J Surg, 41, 1047, 10.1007/s00268-016-3831-4 · DOI
  4. Li, 2009, Symptomatic gallstones after sleeve gastrectomy., Surg Endosc, 23, 2488, 10.1007/s00464-009-0422-6 · DOI
  5. Fraser, 2009, Conversion in laparoscopic cholecystectomy after gastric resection: a 15-year review., Can J Surg, 52, 463
  6. Sasaki, 2008, Laparoscopic cholecystectomy in patients with a history of gastrectomy., Surg Today, 38, 790, 10.1007/s00595-007-3726-y · DOI
  7. Moreels, 2013, ERCP in the patient with surgically altered anatomy., Curr Gastroenterol Rep, 15, 343, 10.1007/s11894-013-0343-3 · DOI
  8. Iglézias Brandão de Oliveira, 2003, Impact of rapid weight reduction on risk of cholelithiasis after bariatric surgery., Obes Surg, 13, 625, 10.1381/096089203322190862 · DOI
  9. Ura, 1992, Antral control of gallbladder cyclic motor activity in the fasting state., Gastroenterology, 102, 295, 10.1016/0016-5085(92)91813-J · DOI
  10. Rehnberg, 1985, Gallstone disease following antrectomy and gastroduodenostomy with or without vagotomy., Ann Surg, 201, 315, 10.1097/00000658-198503000-00010 · DOI
  11. Yi, 2007, Surgical anatomy of innervation of the gallbladder in humans and Suncus murinus with special reference to morphological understanding of gallstone formation after gastrectomy., World J Gastroenterol, 13, 2066, 10.3748/wjg.v13.i14.2066 · DOI
  12. Pezzolla, 1993, Influence of the method of digestive tract reconstruction on gallstone development after total gastrectomy for gastric cancer., Am J Surg, 166, 6, 10.1016/S0002-9610(05)80573-2 · DOI
  13. Takahashi, 1986, Impaired contractile motility of the gallbladder after gastrectomy., Am J Gastroenterol, 81, 672
  14. Inoue, 1987, Release of cholecystokinin and gallbladder contraction before and after gastrectomy., Ann Surg, 205, 27
  15. Portincasa, 2000, The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study., Am J Gastroenterol, 95, 3444, 10.1111/j.1572-0241.2000.03282.x · DOI
  16. Bencini, 2019, The Cholegas trial: long-term results of prophylactic cholecystectomy during gastrectomy for cancer—a randomized-controlled trial., Gastric Cancer, 22, 632, 10.1007/s10120-018-0879-x · DOI
  17. Dakour-Aridi, 2017, Safety of concomitant cholecystectomy at the time of laparoscopic sleeve gastrectomy: analysis of the American College of Surgeons National Surgical Quality Improvement Program database., Surg Obes Relat Dis, 13, 934, 10.1016/j.soard.2016.12.012 · DOI
  18. Yardimci, 2018, Is concomitant cholecystectomy necessary for asymptomatic cholelithiasis during laparoscopic sleeve gastrectomy?, Obes Surg, 28, 469, 10.1007/s11695-017-2867-3 · DOI
  19. Ruhl, 2013, Relationship of non-alcoholic fatty liver disease with cholecystectomy in the US population., Am J Gastroenterol, 108, 952, 10.1038/ajg.2013.70 · DOI
  20. Ammori, 2001, Laparoscopic cholecystectomy in morbidly obese patients., Surg Endosc, 15, 1336, 10.1007/s004640000019 · DOI · Paper page
  21. Coupaye, 2017, Evaluation of incidence of cholelithiasis after bariatric surgery in subjects treated or not treated with ursodeoxycholic acid., Surg Obes Relat Dis, 13, 681, 10.1016/j.soard.2016.11.022 · DOI · Paper page
  22. Uy, 2008, Ursodeoxycholic acid in the prevention of gallstone formation after bariatric surgery: a meta-analysis., Obes Surg, 18, 1532, 10.1007/s11695-008-9587-7 · DOI · Paper page
  23. Wudel, 2002, Prevention of gallstone formation in morbidly obese patients undergoing rapid weight loss: results of a randomized controlled pilot study., J Surg Res, 102, 50, 10.1006/jsre.2001.6322 · DOI · Paper page
  24. Williams, 1993, A double-blind placebo-controlled trial of ursodeoxycholic acid in the prevention of gallstones during weight loss after vertical banded gastroplasty., Obes Surg, 3, 257, 10.1381/096089293765559278 · DOI · Paper page
  25. Abdallah, 2017, Role of ursodeoxycholic acid in the prevention of gallstone formation after laparoscopic sleeve gastrectomy., Surg Today, 47, 844, 10.1007/s00595-016-1446-x · DOI · Paper page
  26. van de Heijning, 1999, Effects of ursodeoxycholic acid therapy on in vitro gallbladder contractility in patients with cholesterol gallstones., Dig Dis Sci, 44, 190, 10.1023/A:1026635124115 · DOI
  27. Guarino, 2007, Ursodeoxycholic acid improves muscle contractility and inflammation in symptomatic gallbladders with cholesterol gallstones., Gut, 56, 815, 10.1136/gut.2006.109934 · DOI
  28. Jazrawi, 1994, Kinetics of hepatic bile acid handling in cholestatic liver disease: effect of ursodeoxycholic acid., Gastroenterology, 106, 134, 10.1016/S0016-5085(94)94899-2 · DOI
  29. Paumgartner, 2002, Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited., Hepatology, 36, 525, 10.1053/jhep.2002.36088 · DOI · Paper page
  30. World Medical Association, 2013, World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects., JAMA, 310, 2191, 10.1001/jama.2013.281053 · DOI · Paper page
  31. Oken, 1982, Toxicity and response criteria of the Eastern Cooperative Oncology Group., Am J Clin Oncol, 5, 649, 10.1097/00000421-198212000-00014 · DOI
  32. Bortoff, 2000, Gallbladder stones: imaging and intervention., Radiographics, 20, 751, 10.1148/radiographics.20.3.g00ma16751 · DOI
  33. Sugerman, 1995, A multicenter, placebo-controlled, randomized, double-blind, prospective trial of prophylactic ursodiol for the prevention of gallstone formation following gastric-bypass–induced rapid weight loss., Am J Surg, 169, 91, 10.1016/S0002-9610(99)80115-9 · DOI · Paper page
  34. Inoue, 1992, Gallbladder sludge and stone formation in relation to contractile function after gastrectomy: a prospective study., Ann Surg, 215, 19, 10.1097/00000658-199201000-00002 · DOI
  35. Sakamaki, 2016, Current practice on multiplicity adjustment and sample size calculation in multi-arm clinical trials: an industry survey in Japan., Ther Innov Regul Sci, 50, 846, 10.1177/2168479016651660 · DOI
  36. Boerlage, 2017, Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial)., BMC Gastroenterol, 17, 164, 10.1186/s12876-017-0674-x · DOI · Paper page
  37. Park, 2004, Changing patterns of gallstone disease in Korea., World J Surg, 28, 206, 10.1007/s00268-003-6879-x · DOI
  38. Kim, 2017, Actual 5-year nutritional outcomes of patients with gastric cancer., J Gastric Cancer, 17, 99, 10.5230/jgc.2017.17.e12 · DOI
  39. Warttig, 2014, Diagnosis and management of gallstone disease: summary of NICE guidance., BMJ, 349, g6241, 10.1136/bmj.g6241 · DOI
  40. Tomida, 1999, Long-term ursodeoxycholic acid therapy is associated with reduced risk of biliary pain and acute cholecystitis in patients with gallbladder stones: a cohort analysis., Hepatology, 30, 6, 10.1002/(ISSN)1527-3350 · DOI
  41. Hempfling, 2003, Systematic review: ursodeoxycholic acid—adverse effects and drug interactions., Aliment Pharmacol Ther, 18, 963, 10.1046/j.1365-2036.2003.01792.x · DOI

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Metadata

Authors
Lee, S. H., Jang, D. K., Yoo, M.-W., Hwang, S.-H., Ryu, S.-Y., Kwon, O. K., Hur, H., Man Yoon, H., Eom, B. W., Ahn, H. S., Son, T., Song, K. Y., Lee, H. H., Choi, M.-G., An, J. Y., Lee, S.-I., Lee, K. H., Ahn, S., Park, Y. S., Park, D. J., & for the Efficacy and Safety of DWJ1319 in the Prevention of Gallstone Formation after Gastrectomy in Patient with Gastric Cancer: A Multicenter, R.
Venue
JAMA Surgery
Publisher
American Medical Association (AMA)
Published
2020-08-01
Volume
155
Issue
8
Pages
703
ISSN
2168-6254
DOI
10.1001/jamasurg.2020.1501
PMC
PMC7301302
Cited by
51
References
2
Language
en

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CoChat. (2026). Citation check: Efficacy and Safety of Ursodeoxycholic Acid for the Prevention of Gallstone Formation After Gastrectomy in Patients With Gastric Cancer: The PEGASUS-D Randomized Clinical Trial. https://app.cochat.ai/papers/10.1001/jamasurg.2020.1501
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Lee, S. H., Jang, D. K., Yoo, M.-W., Hwang, S.-H., Ryu, S.-Y., Kwon, O. K., Hur, H., Man Yoon, H., Eom, B. W., Ahn, H. S., Son, T., Song, K. Y., Lee, H. H., Choi, M.-G., An, J. Y., Lee, S.-I., Lee, K. H., Ahn, S., Park, Y. S., . . . for the Efficacy and Safety of DWJ1319 in the Prevention of Gallstone Formation after Gastrectomy in Patient with Gastric Cancer: A Multicenter, R. (2020). Efficacy and Safety of Ursodeoxycholic Acid for the Prevention of Gallstone Formation After Gastrectomy in Patients With Gastric Cancer: The PEGASUS-D Randomized Clinical Trial. JAMA Surgery. https://doi.org/10.1001/jamasurg.2020.1501