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Cited by 44

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Improvement of interferon-γ sialylation in Chinese hamster ovary cell culture by feeding ofN-acetylmannosamine

Gu, Xuejun, Wang, Daniel I. C.·1998·Biotechnology and Bioengineering

Abstract

Gas transfer and mixing were characterized in a 32-L bubble column reactor equipped with a commercially available rubber membrane diffuser. The performance of the membrane diffuser indicates that the slits in the membrane are best described as holes with elastic lids, acting as valves cutting off bubbles from the gas stream. The membrane diffuser thus functions as a one-way valve preventing backflow of liquid. Our design of the bottom plate of the reactor enabled us to optimize the aeration by changing the tension of the membrane. We thereby achieved mass transfer coefficients higher than those previously reported in bubble columns. A strong dependence of mass transfer on gas holdup and bubble size was indicated by estimates based on these two variables. The microalga, Rhodomonas sp. , sensitive to chemical and physical stress, was maintained for 8 months in continuous culture with a productivity identical to cultures grown in stirred tank reactors. Copyright 1998 John Wiley & Sons, Inc.

Overview

Integrity signals

Registry

Crossref · 10.1002/(sici)1097-0290(19980620)58:6<642::aid-bit10>3.0.co;2-9

Cites

28 of 28 references verified0 citation errors · 0 not checkable

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Citations

Cites

Show all 28 references

Research works printed but not linked: 38

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Metadata

Authors
Gu, X., & Wang, D. I. C.
Venue
Biotechnology and Bioengineering
Publisher
Wiley
Published
1998-06-20
Volume
58
Issue
6
Pages
642-648
ISSN
  • 0006-3592
  • 1097-0290
References
28
Language
en

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This page
CoChat. (2026). Citation check: Improvement of interferon-γ sialylation in Chinese hamster ovary cell culture by feeding ofN-acetylmannosamine. https://app.cochat.ai/papers/10.1002/(sici)1097-0290(19980620)58:6
The paper
Gu, X., & Wang, D. I. C. (1998). Improvement of interferon-γ sialylation in Chinese hamster ovary cell culture by feeding ofN-acetylmannosamine. Biotechnology and Bioengineering. https://doi.org/10.1002/(sici)1097-0290(19980620)58%3A6

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.