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Cited by 25Ovarian function and disordersTreatment of Major DepressionMaternal Mental Health During Pregnancy and Postpartum

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Antidepressants for polycystic ovary syndrome

Open access
Zhuang, Jing, Wang, Xianding, Xu, Liangzhi, Wu, Taixiang, Kang, Deying·2013·Cochrane Database of Systematic Reviews
DOI 10.1002/14651858.cd008575.pub2PMC PMC7390273
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Abstract

Background The prevalence of depression in women with polycystic ovary syndrome (PCOS) is high; one study has shown it to be four times that of women without PCOS. Therefore, systematic evaluation of the effectiveness and safety of antidepressants for women with PCOS is important. Objectives To evaluate the effectiveness and safety of antidepressants in treating depression and other symptoms in women with PCOS. Search methods We searched the following databases from inception to June 2012: the Cochrane Menstrual Disorders and Subfertility Group Trials Register, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, PsycINFO and Chinese National Knowledge Infrastructure, the metaRegister of Controlled Trials (controlled-trials.com), the National Institute of Health Clinical Trials register (clinicaltrials.gov) and the World Health Organization International Trials Registry Platform search portal (www.who.int/trialsearch/Default.aspx). Selection criteria Only randomised controlled trials (RCTs) studying the effectiveness and safety of antidepressants for women with PCOS were included in this review. Data collection and analysis The methodological quality of the trials was assessed independently by two review authors, in parallel with data extraction. The risk of bias in the included study was assessed in six domains: 1. sequence generation; 2. allocation concealment; 3. blinding of participants, personnel and outcome assessors; 4. completeness of outcome data; 5.…

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Cited by

Sorted by citations

Metadata

Authors
Zhuang, J., Wang, X., Xu, L., Wu, T., & Kang, D.
Affiliations
  • Sichuan University (CN)
  • West China Second University Hospital of Sichuan University (CN)
ORCID
Venue
Cochrane Database of Systematic Reviews
Publisher
Wiley
Published
2013-05-31
Volume
2013
Issue
6
Pages
CD008575-CD008575
ISSN
  • 1361-6137 (ISSN-L)
  • 1465-1858
DOI
10.1002/14651858.cd008575.pub2
PMC
PMC7390273
OpenAlex
W1665627024
Cited by
25
References
4
Citations by year
2026: 1 · 2025: 5 · 2024: 3 · 2023: 4 · 2022: 2 · 2021: 2 · 2020: 1 · 2018: 3 · 2016: 1 · 2015: 1 · 2013: 1
FWCI
0.16
Type
journal article
Language
en
Open access
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords
antidepressants, polycystic ovary syndrome, depression, mood disorders, sibutramine, fluoxetine, quality of life, adverse events, women's mental health
MeSH terms
Antidepressive Agents, Cyclobutanes, Depression, Female, Fluoxetine, Humans, Polycystic Ovary Syndrome, Randomized Controlled Trials as Topic

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