Interventions for preventing delirium in older people in institutional long-term care
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Background Delirium is a common and distressing complication of a range of stressor events including infection, new medications and environment change that is often experienced by older people with frailty and dementia. Older people living in institutional long-term care (LTC)are at high risk of delirium, which increases the risk of admission to hospital, development of or worsening of dementia, and mortality.Delirium is also associated with substantial healthcare costs. Although it is possible to prevent delirium in the hospital setting by providing multicomponent delirium prevention interventions it is currently unclear whether interventions to prevent delirium in LTCare effective. Objectives To assess the effectiveness of interventions for preventing delirium in older people in long term care. Search methods We searched ALOIS (www.medicine.ox.ac.uk/alois) - the Cochrane Dementia and Cognitive Improvement Group's Specialised Register- on 23 April 2013. The search was as sensitive as possible to identify all studies on ALOIS relating to delirium. We ran additional separate searches in major healthcare databases, trial registers, the Cochrane Central Register of Controlled Trials (CENTRAL) and grey literature sources, to ensure that the search was as comprehensive as possible. Selection criteria We included randomised controlled trials (RCTs) and cluster-randomised controlled trials (cluster-RCTs) of single- and multi componentn on-pharmacological and pharmacological interven…
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A single, small, low-quality trial showed no significant effect of hydration on the incidence of delirium in nursing homes.
“A single, small, low-quality trial showed no significant effect of hydration on the incidence of delirium.”
From ESPEN practical guideline: Clinical nutrition and hydration in geriatrics (2022) · cites this paper as [194]
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- Authors
- Clegg, A., Siddiqi, N., Heaven, A., Young, J., & Holt, R.
- Affiliations
- University of Leeds (GB)
- Bradford Institute for Health Research (GB)
- Bradford Royal Infirmary (GB)
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- Wiley
- Published
- 2014-01-31
- Volume
- 4
- Issue
- 1
- Pages
- CD009537-CD009537
- ISSN
- 1361-6137 (ISSN-L)
- 1465-1858
- PMC
- PMC6478111
- OpenAlex
- W1567489802
- Cited by
- 100
- References
- 63
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 14 · 2021: 9 · 2020: 16 · 2019: 11 · 2018: 7 · 2017: 11 · 2016: 7 · 2015: 7 · 2014: 6
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Update notices
- new_version (2019-04-23)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute for Health and Care Research (PB-PG-0610-22068)
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- delirium prevention, long-term care facilities, older adults, non-pharmacological treatment, hydration, dementia, activities of daily living, quality of life, frailty, nursing homes, delirium incidence, delirium severity, dementia incidence, adverse outcomes, risk of bias, trial reporting quality, multicomponent intervention, pharmacological interventions, mortality, health care costs
- MeSH terms
- Aged, Delirium, Fluid Therapy, Humans, Institutionalization, Long-Term Care, Randomized Controlled Trials as Topic, Frail Elderly, Medication Reconciliation
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