Psychosocial interventions for fatigue during cancer treatment with palliative intent
Abstract
This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of psychosocial interventions for fatigue in patients with incurable cancer receiving cancer treatment with palliative intent.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Efficacious interventions designed to reduce PARPi-related fatigue interference are lacking.
“Despite the benefits of taking PARPi and the marked fatigue side effects, efficacious interventions designed to reduce PARPi-related fatigue interference are lacking.”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [10]
A Cochrane review found very low quality evidence to support the efficacy of interventions for fatigue in late-stage cancer of any type.
“More broadly, a Cochrane review found ' very low quality evidence ' to support the efficacy of interventions for fatigue in late-stage cancer of any type, indicating a need for further research and innovation [10].”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [10]
A recent Cochrane meta-analysis found few trials and 'very low-quality evidence' for enduring fatigue benefits from cognitive behavioral therapy.
“a recent Cochrane meta-analysis found few trials and ' very low-quality evidence ' for enduring fatigue benefits from cognitive behavioral therapy [10]”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [10]
This intervention was one of the first to test a fully remote fatigue-focused intervention among patients with metastatic cancer.
“was oneof the first to test a fully remote fatigue-focused intervention among patients with metastatic cancer [10].”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [10]
Prior studies have documented significant reductions in fatigue at first follow-up but not post-intervention or second follow-up.
“While prior studies have documented significant reductions in fatigue at first follow-up but not post-intervention or second follow-up [10]”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [10]
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · see citing works
Self-efficacy: the exercise of control
(1997) · Choice Reviews Online · doi:10.5860/choice.35-1826 · Cited by 24,409 · see citing works
The generalizability of the psychoanalytic concept of the working alliance.
Bordin, E. S. (1979) · Psychotherapy: Theory, Research & Practice · doi:10.1037/h0085885 · Cited by 5,238 · see citing works
Cognitive Therapy and the Emotional Disorders
Jaffe, B. (1977) · Psychosomatics · doi:10.1016/s0033-3182(77)71107-7 · Cited by 4,722 · see citing works
Principles of behavior modification
Bandura, A. (1969) · Medical Entomology and Zoology · Cited by 4,631 · see citing works
Bergin and Garfield's Handbook of Psychotherapy and Behavior Change
Lambert, M. J. (2003) · Cited by 3,383 · see citing works
Relation of the therapeutic alliance with outcome and other variables: a meta-analytic review
Martin, D. J., Garske, J. P., & Davis, M. K. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.68.3.438 · Cited by 3,355 · see citing works
(2011) · Cited by 2,032 · see citing works
The Great Psychotherapy Debate: Models Methods and Findings
Horvath, A. O. (2002) · Psychotherapy Research · doi:10.1093/ptr/12.1.108 · Cited by 1,705 · see citing works
Exercise for the management of cancer-related fatigue in adults
Cramp, F., & Byron-Daniel, J. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006145.pub3 · Cited by 1,096 · see citing works
Symptom Prevalence in Patients with Incurable Cancer: A Systematic Review
Teunissen, S. C. C. M., Wesker, W., Kruitwagen, C., de Haes, H. C. J. M., Voest, E. E., & de Graeff, A. (2007) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2006.10.015 · Cited by 990 · see citing works
Cancer-related fatigue: the scale of the problem
Hofman, M., Ryan, J. L., Figueroa-Moseley, C. D., Jean-Pierre, P., & Morrow, G. R. (2007) · The Oncologist · doi:10.1634/theoncologist.12-s1-4 · Cited by 895 · see citing works
Cognitive therapy: Nature and relation to behavior therapy
Beck, A. T. (1970) · Behavior Therapy · doi:10.1016/s0005-7894(70)80030-2 · Cited by 863 · see citing works
Bower, J. E., Bak, K., Berger, A., Breitbart, W., Escalante, C. P., Ganz, P. A., Schnipper, H. H., Lacchetti, C., Ligibel, J. A., Lyman, G. H., et al. (2014) · Journal of Clinical Oncology · doi:10.1200/jco.2013.53.4495 · Cited by 671 · see citing works
Self-citationFrank, A. F. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810150028006 · Cited by 552 · see citing works
NCCN Practice Guidelines for Cancer-Related Fatigue.
Mock, V., Atkinson, A., Barsevick, A. M., Cella, D. F., Cimprich, B., Cleeland, C. S., Donnelly, J. P., Eisenberger, M. A., Escalante, C. P., Hinds, P. S., et al. (2000) · PubMed · Cited by 480 · see citing works
Self-citationLiving Well at the End of Life: Adapting Health Care to Serious Chronic Illness in Old Age
Lynn, J., & Adamson, D. M. (2003) · RAND Corporation eBooks · doi:10.7249/wp137 · Cited by 451 · see citing works
The concept of the alliance and its role in psychotherapy: Theoretical and empirical considerations.
Gaston, L. (1990) · Psychotherapy · doi:10.1037/0033-3204.27.2.143 · Cited by 408 · see citing works
Gielissen, M. F. M., Verhagen, S., Witjes, F., & Bleijenberg, G. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.06.8270 · Cited by 349 · see citing works
Self-citationA systematic review of the scales used for the measurement of cancer-related fatigue (CRF)
Minton, O., & Stone, P. C. (2008) · Annals of Oncology · doi:10.1093/annonc/mdn537 · Cited by 323 · see citing works
Fatigue in palliative care patients — an EAPC approach
Radbruch, L., Strasser, F., Elsner, F., Gonçalves, F., Loge, J. H., Kaasa, S., Nauck, F., & Stone, P. C. (2008) · Palliative Medicine · doi:10.1177/0269216307085183 · Cited by 318 · see citing works
Fatigue in advanced cancer: a prospective controlled cross-sectional study
Stone, P. C., Hardy, J. R., Broadley, K. E., Tookman, A. J., Kurowska, A., & A’Hern, R. (1999) · British Journal of Cancer · doi:10.1038/sj.bjc.6690236 · Cited by 277 · see citing works
Psychosocial interventions for reducing fatigue during cancer treatment in adults
Goedendorp, M. M., Gielissen, M. F. M., Verhagen, C. A. H. H. V. M., & Bleijenberg, G. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006953.pub2 · Cited by 271 · see citing works
Self-citationBehavioral and Psychosocial Interventions in Diabetes
Peyrot, M., & Rubin, R. R. (2007) · Diabetes Care · doi:10.2337/dc07-1222 · Cited by 247 · see citing works
Pharmacological treatments for fatigue associated with palliative care
Mücke, M., Mochamat, M., Cuhls, H., Peuckmann-Post, V., Minton, O., Stone, P., & Radbruch, L. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006788.pub3 · Cited by 227 · see citing works
Stone, P. C., & Minton, O. (2008) · European Journal of Cancer · doi:10.1016/j.ejca.2008.02.037 · Cited by 225 · see citing works
Fatigue is the most important symptom for advanced cancer patients who have had chemotherapy
Butt, Z., Rosenbloom, S. K., Abernethy, A. P., Beaumont, J. L., Paul, D., Hampton, D., Jacobsen, P. B., Syrjala, K. L., Von Roenn, J. H., & Cella, D. (2008) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2008.0036 · Cited by 195 · see citing works
Self-citationCancer‐related fatigue and its impact on functioning
Minton, O., Berger, A. M., Barsevick, A. M., Cramp, F. L., Goedendorp, M. M., Mitchell, S. A., & Stone, P. C. (2013) · Cancer · doi:10.1002/cncr.28058 · Cited by 190 · see citing works
Self-citationTanaka, K., Akechi, T., Okuyama, T., Nishiwaki, Y., & Uchitomi, Y. (2002) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(02)00376-7 · Cited by 166 · see citing works
A scale for rating the quality of psychological trials for pain
Yates, S. L., Morley, S., Eccleston, C., & de C. Williams, A. C. (2005) · Pain · doi:10.1016/j.pain.2005.06.018 · Cited by 150 · see citing works
Fatigue in patients with advanced cancer: A review
Barnes, E. A., & Bruera, E. D. (2002) · International Journal of Gynecological Cancer · doi:10.1046/j.1525-1438.2002.t01-1-01147.x · Cited by 135 · see citing works
Chalder, T., Goldsmith, K. A., White, P. D., Sharpe, M., & Pickles, A. R. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(14)00069-8 · Cited by 134 · see citing works
Knoop, H., van Kessel, K., & Moss-Morris, R. E. (2011) · Psychological Medicine · doi:10.1017/s0033291711000924 · Cited by 124 · see citing works
Self-citationItaliano, A., Massard, C., Bahleda, R., Vataire, A. L., Deutsch, É., Magné, N., Pignon, J., Vassal, G., Armand, J., & Soria, J. (2007) · Annals of Oncology · doi:10.1093/annonc/mdm548 · Cited by 111 · see citing works
Cognitive therapy versus systematic desensitization: Is one treatment superior?
Berman, J. S., Miller, R. C., & Massman, P. J. (1985) · Psychological Bulletin · doi:10.1037/0033-2909.97.3.451 · Cited by 99 · see citing works
Benefit in phase 1 oncology trials: therapeutic misconception or reasonable treatment option?
Miller, F. G., & Joffe, S. (2008) · Clinical Trials · doi:10.1177/1740774508097576 · Cited by 83 · see citing works
The Psychological Practitioner as a Teacher: A Theoretical-Historical and Practical Review
Authier, J., Gustafson, K., Guerney, B. G., & Kasdorf, J. A. (1975) · The Counseling Psychologist · doi:10.1177/001100007500500209 · Cited by 65 · see citing works
Wiborg, J. F., Knoop, H., Prins, J. B., & Bleijenberg, G. (2011) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2010.12.011 · Cited by 56 · see citing works
Self-citationWiborg, J. F., Knoop, H., Frank, L. E., & Bleijenberg, G. (2012) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2012.01.018 · Cited by 54 · see citing works
Self-citationPrinsen, H., Bleijenberg, G., Heijmen, L., Zwarts, M. J., Leer, J. W. H., Heerschap, A., Hopman, M. T. E., & van Laarhoven, H. W. M. (2013) · Supportive Care in Cancer · doi:10.1007/s00520-013-1784-9 · Cited by 46 · see citing works
Self-citationDragioti, E., Dimoliatis, I., & Evangelou, E. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-007206 · Cited by 44 · see citing works
Peters, M. E. W. J., Goedendorp, M. M., Verhagen, S. A. H. H. V. M., van der Graaf, W. T. A., & Bleijenberg, G. (2014) · Psycho-Oncology · doi:10.1002/pon.3481 · Cited by 33 · see citing works
Self-citationPaiva, C. E., & Paiva, B. S. R. (2012) · Supportive Care in Cancer · doi:10.1007/s00520-012-1625-2 · Cited by 32 · see citing works
Fatigue in Advanced Cancer: A Prospective Study
Hauser, K., Walsh, D., Rybicki, L. A., Davis, M. P., & Seyidova-Khoshknabi, D. (2008) · American Journal of Hospice and Palliative Medicine® · doi:10.1177/1049909108319267 · Cited by 30 · see citing works
Examining the role of physical activity in reducing postcancer fatigue
Gielissen, M. F. M., Wiborg, J. F., Verhagen, C. A. H. H. V. M., Knoop, H., & Bleijenberg, G. (2011) · Supportive Care in Cancer · doi:10.1007/s00520-011-1227-4 · Cited by 25 · see citing works
Self-citationAn Introduction to Cognitive-Behavior Therapy
Lehman, A. K., & Salovey, P. (1990) · Springer eBooks · doi:10.1007/978-1-4899-2127-7_11 · Cited by 10 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Ahluwalia, S. C., Chen, C. I., Raaen, L. B., Motala, A., Walling, A. M., Chamberlin, M. E., O’Hanlon, C. E., Larkin, J., Lorenz, K., Akinniranye, O., et al. (2018) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2018.09.008 · Cited by 130 · see citing works
Psychological interventions in palliative care
von Blanckenburg, P., & Leppin, N. (2018) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000441 · Cited by 87 · see citing works
Pilot randomized controlled trial of a symptom cluster intervention in advanced cancer.
Wells‐Di Gregorio, S. M., Marks, D. R., DeCola, J., Peng, J., Probst, D., Zaleta, A., Benson, D., Cohn, D. E., Lustberg, M., Carson, W. E., et al. (2019) · Psycho-Oncology · doi:10.1002/pon.4912 · Cited by 52 · see citing works
Li, J., Peng, X., Su, Y., He, Y., Zhang, S., & Hu, X. (2020) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2020.101798 · Cited by 54 · see citing works
Fatigue in Cancer Patients in Palliative Care—A Review on Pharmacological Interventions
Klasson, C., Frankling, M. H., Hagelin, C. L., & Björkhem‐Bergman, L. (2021) · Cancers · doi:10.3390/cancers13050985 · Cited by 45 · see citing works
The relationship between cancer-related fatigue, quality of life and pain among cancer patients
Liu, D., Weng, J., Ke, X., Wu, X.-Y., & Huang, S.-T. (2022) · International Journal of Nursing Sciences · doi:10.1016/j.ijnss.2022.12.006 · Cited by 36 · see citing works
Picariello, F., Hudson, J. L., Moss-Morris, R. E., Macdougall, I. C., & Chilcot, J. (2017) · Health Psychology Review · doi:10.1080/17437199.2017.1298045 · Cited by 34 · see citing works
Dun, L., Xian-Yi, W., & Huang, S.-T. (2022) · Integrative Cancer Therapies · doi:10.1177/15347354221081271 · Cited by 22 · see citing works
Belloni, S., Arrigoni, C., Arcidiacono, M. A., Baroni, I., Conte, G., Dellafiore, F., Ghizzardi, G., Magon, A., Villa, G., & Caruso, R. (2022) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2022.151354 · Cited by 19 · see citing works
Psychosocial Interventions for the Treatment of Cancer-Related Fatigue: An Umbrella Review
Cedenilla, N., Arenillas, J. I. C., Valero, S. A., Guzmán, A. S., & Miralles, P. M. (2023) · Current Oncology · doi:10.3390/curroncol30030226 · Cited by 13 · see citing works
Wood, M. J. M., Walshe, C., & McCullagh, A. (2023) · Palliative & Supportive Care · doi:10.1017/s1478951523000172 · Cited by 13 · see citing works
Wright, A. A., Poort, H., Tavormina, A., Schmiege, S. J., Matulonis, U. A., Campos, S. M., Liu, J. F., Slivjak, E. T., Gilmour, A. L., Salinger, J. M., et al. (2023) · Gynecologic Oncology · doi:10.1016/j.ygyno.2023.08.020 · Cited by 11 · see citing works
Self-citationWang, Y.-W., Ou, Y., Lin, H., Huang, K.-S., Fu, H., Wu, C., Chen, Y., Huang, S., Tu, H., & Tsai, C. (2023) · Cancers · doi:10.3390/cancers15072181 · Cited by 10 · see citing works
Mikkonen, H., Hökkä, M., Saarto, T., Stenberg, J.-H., & Junttila, K. (2025) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2024-005043 · Cited by 5 · see citing works
Stone, P. C., Minton, O., Richardson, A. M., Buckle, P., Enayat, Z. E., Marston, L., & Freemantle, N. (2025) · Health Technology Assessment · doi:10.3310/gjps6321 · Cited by 2 · see citing works
Cognitive behavioural interventions for palliative care in adult patients: A scoping review
Wilaras, A. (2024) · Progress in Palliative Care · doi:10.1080/09699260.2024.2408127 · Cited by 2 · see citing works
Mosher, C. E., Lewson, A. B., Austin-Wright, M., Matthias, M. S., Helft, P. R., Turk, A. A., Loehrer, P. J., Sehdev, A., Al-Hader, A. A., & Johns, S. A. (2025) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2025-005548 · Cited by 1 · see citing works
Mitchell, S. A. (2021) · doi:10.1002/9781119612780.ch34 · Cited by 1 · see citing works
Hays, M., Santisi, H. L., & Mahon, M. M. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780197583838.003.0031
Pandey, S. (2021) · doi:10.1093/med/9780197559321.003.0041
Ebell, H., & Hönig, K. (2023) · Psychotherapie: Praxis · doi:10.1007/978-3-662-64968-8_43
- Authors
- Poort, H., Goedendorp, M. M., Peters, M., Bleijenberg, G., Gielissen, M. F., Jacobsen, P., Verhagen, S., & Knoop, H.
- Affiliations
- Radboud University Medical Center (NL)
- University Medical Center Groningen (NL)
- Moffitt Cancer Center (US)
- ORCID
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- John Wiley & Sons, Ltd
- Published
- 2016-01-08
- ISSN
- 1361-6137 (ISSN-L)
- OpenAlex
- W4247119572
- Cited by
- 21
- References
- 46
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 5 · 2022: 4 · 2021: 3 · 2020: 1 · 2018: 3 · 2017: 1
- Type
- reference entry
- Language
- en
- Update notices
- new_version (2017-07-14)
- Open access
- closed
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Funders
- National Institute for Health and Care Research
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Keywords
- psychosocial interventions, fatigue, cancer-related fatigue, palliative care, incurable cancer, palliative intent, cancer therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review