The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
PEGylated Micelle Nanoparticles Encapsulating a Non‐Fluorescent Near‐Infrared Organic Dye as a Safe and Highly‐Effective Photothermal Agent for In Vivo Cancer Therapy
Abstract
Photothermal therapy (PTT), as a minimally invasive and highly effective cancer treatment approach, has received widespread attention in recent years. Tremendous effort has been devoted to explore various types of photothermal agents with high near‐infrared (NIR) absorbance for PTT cancer treatment. Despite many exciting progresses in the area, effective yet safe photothermal agents with good biocompatibility and biodegradability are still highly desired. In this work, a new organic PTT agent based on polyethylene glycol (PEG) coated micelle nanoparticles encapsulating a heptamethine indocyanine dye IR825 is developed, showing a strong NIR absorption band and a rather low quantum yield, for in vivo photothermal treatment of cancer. It is found that the IR825–PEG nanoparticles show ultra‐high in vivo tumor uptake after intravenous injection, and appear to be an excellent PTT agent for tumor ablation under a low‐power laser irradiation, without rendering any appreciable toxicity to the treated animals. Compared with inorganic nanomaterials and conjugated polymers being explored in PTT, the NIR‐absorbing micelle nanoparticles presented here may have the least safety concern while showing excellent treatment efficacy, and thus may be a new photothermal agent potentially useful in clinical applications.
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Freestanding palladium nanosheets with plasmonic and catalytic properties
Huang, X., Tang, S., Mu, X., Dai, Y., Chen, G., Zhou, Z., Ruan, F., Yang, Z., & Zheng, N. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2010.235 · Cited by 1,602
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
Cited by
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164
Qi, J., Sun, C., Zebibula, A., Zhang, H., Kwok, R. T. K., Zhao, X., Xi, W., Lam, J. W. Y., Qian, J., & Tang, B. Z. (2018) · Advanced Materials · doi:10.1002/adma.201706856 · Cited by 418
A Dual‐Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy
Wang, H., Chang, J., Shi, M., Pan, W., Li, N., & Tang, B. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201811273 · Cited by 325
Zhang, S., Guo, W., Wei, J., Li, C., Liang, X.-J., & Yin, M. (2017) · ACS Nano · doi:10.1021/acsnano.6b08720 · Cited by 284
Song, X., Zhang, R., Liang, C., Chen, Q., Gong, H., & Liu, Z. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.04.001 · Cited by 101
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Metadata
- Authors
- Cheng, L., He, W., Gong, H., Wang, C., Chen, Q., Cheng, Z., & Liu, Z.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2013-06-13
- Volume
- 23
- Issue
- 47
- Pages
- 5893-5902
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2016081404
- Cited by
- 277
- References
- 2
- FWCI
- 14.17
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cheng, L., He, W., Gong, H., Wang, C., Chen, Q., Cheng, Z., & Liu, Z. (2013). PEGylated Micelle Nanoparticles Encapsulating a Non‐Fluorescent Near‐Infrared Organic Dye as a Safe and Highly‐Effective Photothermal Agent for In Vivo Cancer Therapy. Advanced Functional Materials. https://doi.org/10.1002/adfm.201301045
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