The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Metabolizable Bi2Se3 Nanoplates: Biodistribution, Toxicity, and Uses for Cancer Radiation Therapy and Imaging
Open accessAbstract
Bi, a high atomic number element, has a high photoelectric absorption coefficient, and Se has anticancer activity. Hence, their compound chalcogenide (Bi 2 Se 3) deserves a thorough investigation for biomedical applications. This study reveals that Bi 2 Se 3 nanoplates (54 nm wide) protected with poly(vinylpyrollidone) (PVP) could be presumed to have low toxicity even at a high dose of 20 mg/kg in mice. This conclusion is made through studies on the biodistribution and 90‐day long term in vivo clearance of the nanoplates. The liver and spleen are dominant organs for accumulation of the nanoplates, which is mainly due to RES absorption. 93% of the nanoplates are cleared after 90 days of treatment. Concentrations of Bi and Se in tumor tissue continuously increased until 72 h after intraperitoneal injection into mice. Such selective accumulation of Bi is utilized to enhance the contrast of X‐ray computerized tomography (CT) images. Bi element concentrated in a tumor leads to damage on the tumor cells when exposed to gamma radiation. Growth of the tumor is significantly delayed and stopped in 16 days after the tumor is treated by radiation with Bi 2 Se 3 nanoplates. This work clearly shows that Bi 2 Se 3 nanoplates may be used for cancer radiation therapy and CT imaging. The nanoplates deserve further study for biological and medical applications.
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Cites
Colloquium : Topological insulators
Hasan, M. Z., & Kane, C. L. (2010) · Reviews of Modern Physics · doi:10.1103/revmodphys.82.3045 · Cited by 19,930
Topological insulators and superconductors
Qi, X.-L., & Zhang, S.-C. (2011) · Reviews of Modern Physics · doi:10.1103/revmodphys.83.1057 · Cited by 14,394
Toxic potential of materials at the nanolevel
Nel, A., Xia, T., Mädler, L., & Li, N. (2006) · Science · doi:10.1126/science.1114397 · Cited by 9,324
Understanding biophysicochemical interactions at the nano–bio interface
Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., Klaessig, F., Castranova, V., & Thompson, M. (2009) · Nature Materials · doi:10.1038/nmat2442 · Cited by 7,083
Topological insulators in Bi2Se3, Bi2Te3 and Sb2Te3 with a single Dirac cone on the surface
Zhang, H., Liu, C.-X., Qi, X.-L., Dai, X., Fang, Z., & Zhang, S.-C. (2009) · Nature Physics · doi:10.1038/nphys1270 · Cited by 6,359
Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells
Chithrani, B. D., Ghazani, A. A., & Chan, W. C. W. (2006) · Nano Letters · doi:10.1021/nl052396o · Cited by 4,879
Renal clearance of quantum dots
Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476
Observation of a large-gap topological-insulator class with a single Dirac cone on the surface
Xia, Y., Qian, D., Hsieh, D., Wray, L., Pal, A., Lin, H., Bansil, A., Grauer, D., Hor, Y. S., Cava, R. J., et al. (2009) · Nature Physics · doi:10.1038/nphys1274 · Cited by 3,765
The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems
Albanese, A., Tang, P. S., & Chan, W. C. W. (2012) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071811-150124 · Cited by 3,633
Experimental Realization of a Three-Dimensional Topological Insulator, Bi 2 Te 3
Chen, Y. L., Analytis, J. G., Chu, J.-H., Liu, Z. K., Mo, S.-K., Qi, X. L., Zhang, H. J., Lu, D. H., Dai, X., Fang, Z., et al. (2009) · Science · doi:10.1126/science.1173034 · Cited by 3,585
Cited by
Song, G., Liang, C., Yi, X., Zhao, Q., Cheng, L., Yang, K., & Liu, Z. (2016) · Advanced Materials · doi:10.1002/adma.201504617 · Cited by 587
New Generation Cadmium-Free Quantum Dots for Biophotonics and Nanomedicine
Xu, G., Zeng, S., Zhang, B., Swihart, M. T., Yong, K.-T., & Prasad, P. N. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00290 · Cited by 587
Shahbazi, M.-A., Faghfouri, L., Ferreira, M. P. A., Figueiredo, P., Maleki, H., Sefat, F., Hirvonen, J., & Santos, H. A. (2020) · Chemical Society Reviews · doi:10.1039/c9cs00283a · Cited by 523
Song, G., Chen, Y., Liang, C., Yi, X., Liu, J., Sun, X., Shen, S., Yang, K., & Liu, Z. (2016) · Advanced Materials · doi:10.1002/adma.201602111 · Cited by 394
Bilynsky, C., Millot, N., & Papa, A. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10256 · Cited by 52
Metadata
- Authors
- Zhang, X., Chen, J., Min, Y., Park, G. B., Shen, X., Song, S., Sun, Y., Wang, H., Long, W., Xie, J., Gao, K., Zhang, L., Fan, S., Fan, F., & Jeong, U.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2013-11-27
- Volume
- 24
- Issue
- 12
- Pages
- 1718-1729
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2083111248
- Cited by
- 263
- References
- 72
- FWCI
- 8.68
- Type
- journal article
- Language
- en
- Open access
- green
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- Zhang, X., Chen, J., Min, Y., Park, G. B., Shen, X., Song, S., Sun, Y., Wang, H., Long, W., Xie, J., Gao, K., Zhang, L., Fan, S., Fan, F., & Jeong, U. (2014). Metabolizable Bi2Se3 Nanoplates: Biodistribution, Toxicity, and Uses for Cancer Radiation Therapy and Imaging. Advanced Functional Materials. https://doi.org/10.1002/adfm.201302312
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