The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Polydopamine as a Biocompatible Multifunctional Nanocarrier for Combined Radioisotope Therapy and Chemotherapy of Cancer
Abstract
Development of biodegradable nanomaterials for drug delivery and cancer theranostics has attracted great attention in recent years. In this work, polydopamine (PDA), a biocompatible polymer, is developed as a promising carrier for loading of both radionuclides and an anticancer drug to realize nuclear‐imaging‐guided combined radioisotope therapy (RIT) and chemotherapy of cancer in one system. It is found that PDA nanoparticles after modification with poly(ethylene glycol) (PEG) can successfully load several different radionuclides such as 99m Tc and 131 I, as well as an anticancer drug doxorubicin (DOX). While labeling PDA‐PEG with 99m Tc (99m Tc‐PDA‐PEG) enables in vivo single photon emission computed tomography imaging, nanoparticles co‐loaded with 131 I and DOX (131 I‐PDA‐PEG/DOX) can be utilized for combined RIT and chemotherapy, which offers effective cancer treatment efficacy in a remarkably synergistic manner, without rendering significant toxicity to the treated animals. Therefore, this study presents an interesting class of biocompatible nanocarriers, which allow the combination of RIT and chemotherapy, the two extensively applied cancer therapeutic strategies, promising for future clinic translations in cancer treatment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mussel-inspired surface chemistry for multifunctional coatings
Lee, H., Dellatore, S. M., Miller, W. M., & Messersmith, P. B. (2007) · Science · doi:10.1126/science.1147241 · Cited by 10,965
Stimuli-responsive nanocarriers for drug delivery
Mura, S., Nicolas, J., & Couvreur, P. (2013) · Nature Materials · doi:10.1038/nmat3776 · Cited by 6,289
Liu, Y., Ai, K., & Lu, L. (2014) · Chemical Reviews · doi:10.1021/cr400407a · Cited by 4,794
PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs
Liu, Z., Robinson, J. T., Sun, X., & Dai, H. (2008) · Journal of the American Chemical Society · doi:10.1021/ja803688x · Cited by 3,589
Self-citationEBCTCG (Early Breast Cancer Trialists' Collaborative Group) (2014) · The Lancet · doi:10.1016/s0140-6736(14)60488-8 · Cited by 2,254
Early Breast Cancer Trialists' Collaborative Group (EBCTCG) (2012) · The Lancet · doi:10.1016/s0140-6736(11)61625-5 · Cited by 2,089
Liu, Y., Ai, K., Liu, J., Deng, M., He, Y., & Lu, L. (2013) · Advanced Materials · doi:10.1002/adma.201204683 · Cited by 2,019
Facile Conjugation of Biomolecules onto Surfaces via Mussel Adhesive Protein Inspired Coatings
Lee, H., Rho, J., & Messersmith, P. B. (2009) · Advanced Materials · doi:10.1002/adma.200801222 · Cited by 1,495
Cited by
Bao, X., Zhao, J., Sun, J., Hu, M., & Yang, X. (2018) · ACS Nano · doi:10.1021/acsnano.8b04022 · Cited by 722
Liu, M., Zeng, G., Wang, K., Wan, Q., Tao, L., Zhang, X., & Wei, Y. (2016) · Nanoscale · doi:10.1039/c5nr09078d · Cited by 561
Metal‐Containing Polydopamine Nanomaterials: Catalysis, Energy, and Theranostics
Wang, Z., Zou, Y., Li, Y., & Cheng, Y. (2020) · Small · doi:10.1002/smll.201907042 · Cited by 459
Meng, Y., Liu, P., Zhou, W., Ding, J., & Liu, J. (2018) · ACS Nano · doi:10.1021/acsnano.8b03019 · Cited by 149
Trackable Mitochondria-Targeting Nanomicellar Loaded with Doxorubicin for Overcoming Drug Resistance
Zhang, Y., Zhang, C., Chen, J., Liu, L., Hu, M., Li, J., & Bi, H. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b07219 · Cited by 109
Metadata
- Authors
- Zhong, X., Yang, K., Dong, Z., Yi, X., Wang, Y., Ge, C., Zhao, Y., & Liu, Z.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2015-11-05
- Volume
- 25
- Issue
- 47
- Pages
- 7327-7336
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2148491656
- Cited by
- 265
- References
- 55
- FWCI
- 21.92
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Polydopamine as a Biocompatible Multifunctional Nanocarrier for Combined Radioisotope Therapy and Chemotherapy of Cancer. https://app.cochat.ai/papers/10.1002/adfm.201503587
- The paper
- Zhong, X., Yang, K., Dong, Z., Yi, X., Wang, Y., Ge, C., Zhao, Y., & Liu, Z. (2015). Polydopamine as a Biocompatible Multifunctional Nanocarrier for Combined Radioisotope Therapy and Chemotherapy of Cancer. Advanced Functional Materials. https://doi.org/10.1002/adfm.201503587
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
