The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Injectable Polypeptide‐Protein Hydrogels for Promoting Infected Wound Healing
Abstract
Protein is the key composition of all tissues, which has also been widely used in tissue engineering due to its superior biocompatibility and low immunogenicity. However, natural protein usually lacks active functions such as vascularization, osteo‐induction, and neural differentiation, which limits its further applications as a functional biomaterial. Here, based on the mimetic extracellular matrix feature of bovine serum albumin, injectable polypeptide‐protein hydrogels with vascularization and antibacterial abilities are constructed successfully via coordinative cross‐linking of sulfydryl groups with silver ions (Ag+) for the regeneration of infected wound. In this protein hydrogel system, (Ag+), acting as crosslinkers, can not only provide a sterile microenvironment and a strong and robust antibacterial ability but also introduce K 2(SL)6 K 2 (KK) polypeptide, which endows the hydrogel with vascularization behavior. Furthermore, the in vivo data show that the polypeptide‐protein hydrogel has a considerable collagen deposition and vascularization abilities in the early stage of wound healing, resulting in rapid new tissue regeneration featured with newly appeared hair follicles. Altogether, this newly developed multifunctional 3D polypeptide‐protein hydrogel with vascularization, antibacterial properties, and hair follicle promotion can be a promising approach in biomedical fields such as infected wound healing.
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Cites
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels
Yue, K., Trujillo-de Santiago, G., Alvarez, M. M., Tamayol, A., Annabi, N., & Khademhosseini, A. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.08.045 · Cited by 3,146
Diabetes and Wound Angiogenesis
Okonkwo, U., & DiPietro, L. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18071419 · Cited by 1,022
Peptide-Labeled Near-Infrared Quantum Dots for Imaging Tumor Vasculature in Living Subjects
Cai, W., Shin, D.-W., Chen, K., Gheysens, O., Cao, Q., Wang, S. X., Gambhir, S. S., & Chen, X. (2006) · Nano Letters · doi:10.1021/nl052405t · Cited by 948
Beyond binding: antibody effector functions in infectious diseases
Lu, L. L., Suscovich, T. J., Fortune, S. M., & Alter, G. (2018) · Nature Reviews Immunology · doi:10.1038/nri.2017.106 · Cited by 825
Mao, C., Xiang, Y., Liu, X., Cui, Z., Yang, X., Yeung, K. W. K., Pan, H., Wang, X., Chu, P. K., & Wu, S. (2017) · ACS Nano · doi:10.1021/acsnano.7b03513 · Cited by 756
A Review of Keratin-Based Biomaterials for Biomedical Applications
Rouse, J. G., & Van Dyke, M. E. (2010) · Materials · doi:10.3390/ma3020999 · Cited by 661
Annabi, N., Rana, D., Shirzaei Sani, E., Portillo-Lara, R., Gifford, J. L., Fares, M. M., Mithieux, S. M., & Weiss, A. S. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.05.011 · Cited by 542
Silkworm silk-based materials and devices generated using bio-nanotechnology
Huang, W., Ling, S., Li, C., Omenetto, F. G., & Kaplan, D. L. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00187a · Cited by 491
The cyclization of peptides and depsipeptides
Davies, J. S. (2003) · Journal of Peptide Science · doi:10.1002/psc.491 · Cited by 450
Thapa, R. K., Diep, D. B., & Tønnesen, H. H. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.12.025 · Cited by 378
Cited by
Design Challenges in Polymeric Scaffolds for Tissue Engineering
Echeverria Molina, M. I., Malollari, K. G., & Komvopoulos, K. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.617141 · Cited by 397
Zhou, L., Zheng, H., Liu, Z., Wang, S., Liu, Z., Chen, F., Zhang, H., Kong, J., Zhou, F., & Zhang, Q. (2021) · ACS Nano · doi:10.1021/acsnano.0c06287 · Cited by 382
Self-citationSun, A., Hu, D., He, X., Ji, X., Li, T., Wei, X., & Qian, Z. (2022) · NPG Asia Materials · doi:10.1038/s41427-022-00434-z · Cited by 74
Metadata
- Authors
- Cheng, L., Cai, Z., Ye, T., Yu, X., Chen, Z., Yan, Y., Qi, J., Wang, L., Liu, Z., Cui, W., & Deng, L.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2020-05-04
- Volume
- 30
- Issue
- 25
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W3021162906
- Cited by
- 267
- References
- 38
- FWCI
- 21.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cheng, L., Cai, Z., Ye, T., Yu, X., Chen, Z., Yan, Y., Qi, J., Wang, L., Liu, Z., Cui, W., & Deng, L. (2020). Injectable Polypeptide‐Protein Hydrogels for Promoting Infected Wound Healing. Advanced Functional Materials. https://doi.org/10.1002/adfm.202001196
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