The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus
Abstract
End-modified poly(β-amino ester)s, easy-to-synthesize degradable polymers, are able to deliver DNA to primary human cells at levels comparable to adenovirus and two orders of magnitude better than the commonly used non-viral vector, polyethylenimine. Small structural changes are found to affect multiple steps of gene delivery including the DNA binding affinity, nanoparticle size, intracellular DNA uptake, and final protein expression. In vivo, these polymer modifications enhance DNA delivery to ovarian tumors.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Design and development of polymers for gene delivery
Pack, D. W., Hoffman, A. S., Pun, S., & Stayton, P. S. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1775 · Cited by 2,568
Cited by
A combinatorial polymer library approach yields insight into nonviral gene delivery
Green, J. J., Langer, R., & Anderson, D. G. (2008) · Accounts of Chemical Research · doi:10.1021/ar7002336 · Cited by 579
Self-citationSurface-Engineered Dendrimers in Gene Delivery
Yang, J., Zhang, Q., Chang, H., & Cheng, Y. (2015) · Chemical Reviews · doi:10.1021/cr500542t · Cited by 429
Yang, F., Cho, S.-W., Son, S. M., Bogatyrev, S. R., Singh, D., Green, J. J., Mei, Y., Park, S., Bhang, S. H., Kim, B.-S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905432106 · Cited by 301
Self-citationGold, Poly(β-amino ester) Nanoparticles for Small Interfering RNA Delivery
Lee, J.-S., Green, J. J., Love, K. T., Sunshine, J., Langer, R., & Anderson, D. G. (2009) · Nano Letters · doi:10.1021/nl9009793 · Cited by 276
Self-citationPolymeric Materials for Gene Delivery and DNA Vaccination
Nguyen, D. N., Green, J. J., Chan, J. M., Langer, R., & Anderson, D. G. (2009) · Advanced Materials · doi:10.1002/adma.200801478 · Cited by 273
Self-citation
Metadata
- Authors
- Green, J. J., Zugates, G. T., Tedford, N. C., Huang, Y. ‐., Griffith, L. G., Lauffenburger, D. A., Sawicki, J. A., Langer, R., & Anderson, D. G.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2007-09-06
- Volume
- 19
- Issue
- 19
- Pages
- 2836-2842
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2061643067
- Cited by
- 168
- References
- 1
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus. https://app.cochat.ai/papers/10.1002/adma.200700371
- The paper
- Green, J. J., Zugates, G. T., Tedford, N. C., Huang, Y. ‐., Griffith, L. G., Lauffenburger, D. A., Sawicki, J. A., Langer, R., & Anderson, D. G. (2007). Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus. Advanced Materials. https://doi.org/10.1002/adma.200700371
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
