The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Peptide Targeted Lipid Nanoparticles for Anticancer Drug Delivery
Abstract
Encapsulating anticancer drugs in nanoparticles has proven to be an effective mechanism to alter the pharmacokinetic and pharmacodynamic profiles of the drugs, leading to clinically useful cancer therapeutics like Doxil and DaunoXome. Underdeveloped tumor vasculature and lymphatics allow these first‐generation nanoparticles to passively accumulate within the tumor, but work to create the next‐generation nanoparticles that actively participate in the tumor targeting process is underway. Lipid nanoparticles functionalized with targeting peptides are among the most often studied. The goal of this article is to review the recently published literature of targeted nanoparticles to highlight successful designs that improved in vivo tumor therapy, and to discuss the current challenges of designing these nanoparticles for effective in vivo performance.
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Cites
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Cited by
Erythrocyte–Platelet Hybrid Membrane Coating for Enhanced Nanoparticle Functionalization
Dehaini, D., Wei, X., Fang, R. H., Masson, S., Angsantikul, P., Luk, B. T., Zhang, Y., Ying, M., Jiang, Y., Kroll, A. V., et al. (2017) · Advanced Materials · doi:10.1002/adma.201606209 · Cited by 769
Tunable Rigidity of (Polymeric Core)–(Lipid Shell) Nanoparticles for Regulated Cellular Uptake
Sun, J., Zhang, L., Wang, J., Feng, Q., Liu, D., Yin, Q., Xu, D., Wei, Y., Ding, B., Shi, X., et al. (2015) · Advanced Materials · doi:10.1002/adma.201404788 · Cited by 486
Application of Light Scattering Techniques to Nanoparticle Characterization and Development
Carvalho, P. M., Felício, M. R., Santos, N. C., Gonçalves, S., & Domingues, M. M. (2018) · Frontiers in Chemistry · doi:10.3389/fchem.2018.00237 · Cited by 402
Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs
Sun, Q., Sun, X., Ma, X., Zhou, Z., Jin, E., Zhang, B., Shen, Y., Van Kirk, E. A., Murdoch, W. J., Lott, J. R., et al. (2014) · Advanced Materials · doi:10.1002/adma.201401554 · Cited by 377
Anticancer cyclometalated complexes of platinum group metals and gold
Cutillas, N., Yellol, G. S., de Haro, C., Vicente, C., Rodríguez, V., & Ruiz, J. (2013) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2013.03.024 · Cited by 332
Metadata
- Authors
- Pearce, T. R., Shroff, K., & Kokkoli, E.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2012-06-05
- Volume
- 24
- Issue
- 28
- Pages
- 3803-3822
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2111436238
- Cited by
- 192
- References
- 7
- FWCI
- 8.42
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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