The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Multistage pH‐Responsive Liposomes for Mitochondrial‐Targeted Anticancer Drug Delivery
Abstract
Zwitterionic oligopeptide liposomes (HHG2C(18)-L) containing a smart lipid (1,5-dioctadecyl-L-glutamyl 2-histidyl-hexahydrobenzoic acid, HHG2C(18)) are developed to overcome the barriers faced by anticancer drugs on the route from the site of injection into the body to the final antitumor target within transport steps with multiple physiological and biological barriers. HHG2C(18)-L show the multistage pH-responsive to the tumor cell (the mitochondria in this case). Their multistage pH response leads to more effective entry of the tumor cell, improved escape from the endolysosomes, and accumulation at the mitochondria (see picture).
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Cites
Albumin-bound formulation of paclitaxel (Abraxane® ABI-007) in the treatment of breast cancer
Tomao, S. (2009) · International Journal of Nanomedicine · doi:10.2147/ijn.s3061 · Cited by 695
Lee, K. S., Chung, H. C., Im, S. A., Park, Y. H., Kim, C. S., Kim, S.-B., Rha, S. Y., Lee, M. Y., & Ro, J. (2008) · Breast Cancer Research and Treatment · doi:10.1007/s10549-007-9591-y · Cited by 541
Cationic charge‐dependent hepatic delivery of amidated serum albumin
Ma, S.-F., Nishikawa, M., Katsumi, H., Yamashita, F., & Hashida, M. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.11.006 · Cited by 66
Cited by
Controlled drug delivery vehicles for cancer treatment and their performance
Senapati, S., Mahanta, A. K., Kumar, S., & Maiti, P. (2018) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-017-0004-3 · Cited by 2,167
The Smart Drug Delivery System and Its Clinical Potential
Liu, D., Yang, F., Xiong, F., & Gu, N. (2016) · Theranostics · doi:10.7150/thno.14858 · Cited by 1,066
Stimuli‐responsive liposomes for drug delivery
Lee, Y., & Thompson, D. H. (2017) · WIREs Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1450 · Cited by 579
El-Sawy, H. S., Al-Abd, A. M., Ahmed, T. A., El-Say, K. M., & Torchilin, V. P. (2018) · ACS Nano · doi:10.1021/acsnano.8b06104 · Cited by 431
Stimuli-responsive nanomaterials for therapeutic protein delivery
Lu, Y., Sun, W., & Gu, Z. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.08.015 · Cited by 415
Metadata
- Authors
- Mo, R., Sun, Q., Xue, J., Li, N., Li, W., Zhang, C., & Ping, Q.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2012-06-08
- Volume
- 24
- Issue
- 27
- Pages
- 3659-3665
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2016129077
- Cited by
- 244
- References
- 3
- FWCI
- 8.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mo, R., Sun, Q., Xue, J., Li, N., Li, W., Zhang, C., & Ping, Q. (2012). Multistage pH‐Responsive Liposomes for Mitochondrial‐Targeted Anticancer Drug Delivery. Advanced Materials. https://doi.org/10.1002/adma.201201498
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