The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Photoconversion‐Tunable Fluorophore Vesicles for Wavelength‐Dependent Photoinduced Cancer Therapy
Abstract
Photoconversion tunability of fluorophore dye is of great interest in cancer nanomedicine such as fluorescence imaging, photodynamic therapy (PDT), and photothermal therapy (PTT). Herein, this paper reports wavelength‐dependent photoconversional polymeric vesicles of boron dipyrromethene (Bodipy) fluorophore for either PDT under 660 nm irradiation or PTT under 785 nm irradiation. After being assembled within polymeric vesicles at a high drug loading, Bodipy molecules aggregate in the conformations of both J‐type and H‐type, thereby causing red‐shifted absorption into near‐infrared region, ultralow radiative transition, and ideal resistance to photobleaching. Such vesicles further possess enhanced blood circulation, preferable tumor accumulation, as well as superior cell uptake as compared to free Bodipy. In particular, the vesicles mainly generate abundant intracellular singlet oxygen for PDT treatment under 660 nm irradiation, while they primarily produce a potent hyperthermia for PTT with tumor ablation through singlet oxygen‐synergized photothermal necrosis under 785 nm irradiation. This approach provides a facile and general strategy to tune photoconversion characteristics of fluorophore dyes for wavelength‐dependent photoinduced cancer therapy.
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An overview of nanoparticles commonly used in fluorescent bioimaging
Wolfbeis, O. S. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00392f · Cited by 1,631
Cheng, Y., Cheng, H., Jiang, C., Qiu, X., Wang, K., Huan, W., Yuan, A., Wu, J., & Hu, Y. (2015) · Nature Communications · doi:10.1038/ncomms9785 · Cited by 941
Polymeric micelles drug delivery system in oncology
Gong, J., Chen, M., Zheng, Y., Wang, S., & Wang, Y. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.12.012 · Cited by 570
Cited by
Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813
Design of superior phototheranostic agents guided by Jablonski diagrams
Feng, G., Zhang, G.-Q., & Ding, D. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00671h · Cited by 783
Min, H., Wang, J., Qi, Y., Zhang, Y., Han, X., Xu, Y., Xu, J., Li, Y., Chen, L., Cheng, K., et al. (2019) · Advanced Materials · doi:10.1002/adma.201808200 · Cited by 394
Supramolecular Photothermal Effects: A Promising Mechanism for Efficient Thermal Conversion
Zhao, L., Liu, Y., Xing, R., & Yan, X. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201909825 · Cited by 339
Controlling the biodistribution and clearance of nanomedicines
Cabral, H., Li, J., Miyata, K., & Kataoka, K. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00138-1 · Cited by 303
Metadata
- Authors
- He, H., Ji, S., He, Y., Zhu, A., Zou, Y., Deng, Y., Ke, H., Yang, H., Zhao, Y., Guo, Z., & Chen, H.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2017-03-15
- Volume
- 29
- Issue
- 19
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2595654921
- Cited by
- 202
- References
- 3
- FWCI
- 14.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- He, H., Ji, S., He, Y., Zhu, A., Zou, Y., Deng, Y., Ke, H., Yang, H., Zhao, Y., Guo, Z., & Chen, H. (2017). Photoconversion‐Tunable Fluorophore Vesicles for Wavelength‐Dependent Photoinduced Cancer Therapy. Advanced Materials. https://doi.org/10.1002/adma.201606690
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