The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Nanoparticles of Metal‐Organic Frameworks: On the Road to In Vivo Efficacy in Biomedicine
Abstract
In the past few years, numerous studies have demonstrated the great potential of nano particles of metal‐organic frameworks (nanoMOFs) at the preclinical level for biomedical applications. Many of them were reported very recently based on their bioactive composition, anticancer application, or from a general drug delivery/theranostic perspective. In this review, the authors aim at providing a global view of the studies that evaluated MOFs' biomedical applications at the preclinical stage, when in vivo tests are described either for pharmacological applications or for toxicity evaluation. The authors first describe the current surface engineering approaches that are crucial to understand the in vivo behavior of the nanoMOFs. Finally, after a detailed and comprehensive analysis of the in vivo studies reported with MOFs so far, and considering the general evolution of the drug delivery science, the authors suggest new directions for future research in the use of nanoMOFs for biomedical applications.
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Cites
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Self-citationBioMOFs: Metal–Organic Frameworks for Biological and Medical Applications
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He, S., Wu, L., Li, X., Sun, H., Xiong, T., Liu, J., Huang, C., Xu, H., Sun, H., Chen, W., et al. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.019 · Cited by 528
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In Vitro Strategies to Vascularize 3D Physiologically Relevant Models
Dellaquila, A., Le Bao, C., Letourneur, D., & Simon‐Yarza, T. (2021) · Advanced Science · doi:10.1002/advs.202100798 · Cited by 115
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Lin, G., Nash, G. T., Luo, T., Ghosh, I., Sohoni, S., Christofferson, A. J., Liu, G., Engel, G. S., & Lin, W. (2023) · Advanced Materials · doi:10.1002/adma.202212069 · Cited by 63
Metadata
- Authors
- Simon‐Yarza, T., Mielcarek, A., Couvreur, P., & Serre, C.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2018-06-06
- Volume
- 30
- Issue
- 37
- Pages
- e1707365-e1707365
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2805982534
- Cited by
- 648
- References
- 12
- FWCI
- 29.57
- Type
- journal article
- Language
- en
- Open access
- closed
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