The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Artificial Super Neutrophils for Inflammation Targeting and HClO Generation against Tumors and Infections
Abstract
Neutrophils are powerful effector leukocytes that play an important role in innate immune systems for opposing tumor progression and ameliorating pathogen infections. Inspired by their distinct functions against tumors and infections, the artificial “super neutrophils” are proposed with excellent inflammation targeting and hypochlorous acid (HClO) generation characteristics for targeting and eliminating malignant tumor cells and pathogens. The “super neutrophils” are fabricated by embedding glucose oxidase (GOx) and chloroperoxidase (CPO) into zeolitic imidazolate framework‐8 (ZIF‐8) for HClO generation via enzymatic cascades, and then encapsulating them with the neutrophil membrane (NM) for inflammation targeting. In vitro and in vivo results indicate that these artificial “super neutrophils” can generate seven times higher reactive HClO than the natural neutrophils for eradicating tumors and infections. The “super neutrophils” demonstrated here with easy fabrication and good neutrophil‐mimicking property exhibit great potential for biomedical applications.
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Cites
Neutrophil recruitment and function in health and inflammation
Kolaczkowska, E., & Kubes, P. (2013) · Nature Reviews Immunology · doi:10.1038/nri3399 · Cited by 5,472
Getting to the site of inflammation: the leukocyte adhesion cascade updated
Ley, K., Laudanna, C., Cybulsky, M. I., & Nourshargh, S. (2007) · Nature Reviews Immunology · doi:10.1038/nri2156 · Cited by 4,354
Microenvironmental regulation of metastasis
Joyce, J. A., & Pollard, J. W. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2618 · Cited by 3,684
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Targeting drugs to tumours using cell membrane-coated nanoparticles
Fang, R. H., Gao, W., & Zhang, L. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-022-00699-x · Cited by 980
Self-citationWang, J., Tang, W., Yang, M., Yin, Y., Li, H., Hu, F., Tang, L., Ma, X., Zhang, Y., & Wang, Y. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120784 · Cited by 317
Metal–Organic‐Framework‐Engineered Enzyme‐Mimetic Catalysts
Ma, L., Jiang, F., Fan, X., Wang, L., He, C., Zhou, M., Li, S., Luo, H., Cheng, C., & Qiu, L. (2020) · Advanced Materials · doi:10.1002/adma.202003065 · Cited by 298
Liu, B., Bian, Y., Liang, S., Yuan, M., Dong, S., He, F., Gai, S., Yang, P., Cheng, Z., & Lin, J. (2022) · ACS Nano · doi:10.1021/acsnano.1c07893 · Cited by 257
Endogenous Hydrogen Sulfide-Triggered MOF-Based Nanoenzyme for Synergic Cancer Therapy
Li, Y., Zhou, J., Wang, L., & Xie, Z. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c08659 · Cited by 125
Metadata
- Authors
- Zhang, C., Zhang, L., Wu, W., Gao, F., Li, R., Song, W., Zhuang, Z., Liu, C., & Zhang, X.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2019-03-29
- Volume
- 31
- Issue
- 19
- Pages
- e1901179-e1901179
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2928674156
- Cited by
- 192
- References
- 4
- FWCI
- 8.77
- Type
- journal article
- Language
- en
- Open access
- closed
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