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Cited by 102Nanoplatforms for cancer theranosticsTreatment of Major DepressionNanoparticle-Based Drug Delivery

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Fast‐Acting Black‐Phosphorus‐Assisted Depression Therapy with Low Toxicity

Jin, Liguo, Hu, Ping, Wang, Yinyin, Wu, Luojia, Qin, Kang, Cheng, Haoxin, Wang, Shuhua, Pan, Bingxing, Xin, Hongbo, Zhang, Wenhua, Wang, Xiaolei·2020·Advanced Materials
DOI 10.1002/adma.201906050
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Abstract

A black phosphorus (BP)‐nanosheet‐based drug‐delivery system containing a therapeutic drug (Fluoxetine, Flu) is synthesized. According to subsequent behavioral, biochemical, and electrophysiological analysis, BP‐Flu, after irradiated with near‐infrared light (808 nm), can significantly reduce the therapy time of depression. Meanwhile, the inherent biotoxicity of Flu is also alleviated.

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Metadata

Authors
Jin, L., Hu, P., Wang, Y., Wu, L., Qin, K., Cheng, H., Wang, S., Pan, B., Xin, H., Zhang, W., & Wang, X.
Affiliations
  • Nanchang University (CN)
  • The National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational Medicine Nanchang University Nanchang Jiangxi 330088 China
  • Laboratory of Fear and Anxiety Disorders Institute of Life Science Nanchang University, Nanchang Nanchang 330031 China
Corresponding author
Wang, Xiaolei
ORCID
Venue
Advanced Materials
Publisher
Wiley
Published
2019-11-28
Volume
32
Issue
2
Pages
e1906050-e1906050
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
DOI
10.1002/adma.201906050
OpenAlex
W2991062903
Cited by
102
References
1
Citations by year
2026: 5 · 2025: 9 · 2024: 20 · 2023: 12 · 2022: 20 · 2021: 25 · 2020: 10 · 2019: 1
FWCI
4.94
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Advanced Materials (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (31860263, 31970953, 81601179, 81760505)
  • Education Department of Jiangxi Province (KJLD14010, 20153BCB23035, 20161ACB21002, 20165BCB19002)
  • Natural Science Foundation of Jiangxi Province (20192ACB21024, 20181ACG70003, 20192BCB23008)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Keywords
black phosphorus nanosheets, depression treatment, fluoxetine, drug delivery systems, near-infrared irradiation, photothermal therapy, antidepressant efficacy, drug toxicity reduction
MeSH terms
Animals, Behavior, Animal, Depression, Drug Carriers, Fluoxetine, Kinetics, Phosphorus, Mice, Electrophysiological Phenomena

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CoChat. (2026). Citation check: Fast‐Acting Black‐Phosphorus‐Assisted Depression Therapy with Low Toxicity. https://app.cochat.ai/papers/10.1002/adma.201906050
The paper
Jin, L., Hu, P., Wang, Y., Wu, L., Qin, K., Cheng, H., Wang, S., Pan, B., Xin, H., Zhang, W., & Wang, X. (2020). Fast‐Acting Black‐Phosphorus‐Assisted Depression Therapy with Low Toxicity. Advanced Materials. https://doi.org/10.1002/adma.201906050