The DOI matches its Crossref record; 161 of the 161 references it cites were found in a registry or an index.
Genetic variants implicated in personality: A review of the more promising candidates
Abstract
Alleles of the serotonin transporter gene ( SERT ) and the dopamine 4 receptor gene ( DRD4 ) were first associated with anxiety‐related and novelty‐seeking personality traits, respectively, in 1996. These early successes precipitated a flood of research into the genetic basis of personality; a quest that has yet to yield decisive answers. Here, both the theoretical and the empirical evidence implicating specific loci—in particular SERT and DRD4—in the development of personality is evaluated. Despite a paucity of statistically significant results following post‐hoc analysis, and an excess of positive results derived from studies with small sample sizes, the existence of a genuine effect is argued for: a gene‐personality relationship rendered periodically latent through genetic epistasis, gene–environment interactions, variation in genetic background, and the presence of other confounding variables. © 2004 Wiley‐Liss, Inc.
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“a single nucleotide polymorphism in the gene coding for the dopamine-4 receptor has been associated with individual variation in novelty seeking and behavioural inhibition in humans and animals”
From Coping styles and behavioural flexibility: towards underlying mechanisms (2010) · cites this paper as Savitz & Ramesar 2004
Citations
Cites
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Cited by
Schaller, M., & Murray, D. R. (2008) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.95.1.212 · Cited by 647
Coping styles and behavioural flexibility: towards underlying mechanisms
Coppens, C. M., de Boer, S. F., & Koolhaas, J. M. (2010) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2010.0217 · Cited by 646
Bipolar and major depressive disorder: Neuroimaging the developmental-degenerative divide
Savitz, J., & Drevets, W. C. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.01.004 · Cited by 494
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Metadata
- Authors
- Savitz, J. B., & Ramesar, R. S.
- Venue
- American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
- Publisher
- Wiley
- Published
- 2004-09-23
- Volume
- 131B
- Issue
- 1
- Pages
- 20-32
- ISSN
- 1552-4841
- 1552-485X
- Cited by
- 114
- References
- 161
- Language
- en
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
