Ancient DNA from a pre‐Columbian Amerindian population
Abstract
Ancient DNA was obtained from skeletal remains from the Norris Farms #36 cemetery, a pre-Columbian archeological site in central Illinois that dates to A.D. 1300. Four mitochondrial DNA (mtDNA) markers were analyzed that delineate the four primary mtDNA lineages found in contemporary Amerindian populations. mtDNA types were determined for 50 individuals; 49 belonged to one of these four lineages. One lineage occurred only in males, suggesting an immigration of maternally related males into this community. There was no significant spatial patterning of mtDNA lineages within the cemetery. This survey of ancient DNA variation in a pre-Columbian population supports the view that the initial colonization of the New World comprised just four primary mtDNA lineages.
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The Norris Farms #36 cemetery was selected for analysis because bone samples from this site had been previously investigated using ancient DNA techniques, and mtDNA haplogroup assignments and HVRI sequences are available for 108 and 52 individuals, respectively, making it the most intensively studied pre-Contact North American site to date.
“The Norris Farms #36 cemetery was selected for analysis because bone samples from this site had been previously investigated using ancient DNA techniques (Stone and Stoneking, 1993, 1998, 1999), and mtDNA haplogroup assignments and HVRI sequences are available for 108 and 52 individuals, respectively, making it the most intensively studied pre‐Contact North American site to date.”
From Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus (2016) · cites this paper as Stone and Stoneking, 1993
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- Authors
- Stone, A. C., & Stoneking, M.
- Affiliations
- Pennsylvania State University (US)
- Corresponding author
- Stoneking, Mark
- Venue
- American Journal of Physical Anthropology
- Publisher
- Wiley
- Published
- 1993-12
- Volume
- 92
- Issue
- 4
- Pages
- 463-471
- ISSN
- 0002-9483 (ISSN-L)
- 1096-8644
- OpenAlex
- W2074866183
- Cited by
- 187
- References
- 36
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2022: 2 · 2021: 22 · 2019: 1 · 2018: 5 · 2017: 1 · 2016: 4 · 2015: 1 · 2014: 4 · 2013: 4 · 2012: 5
- FWCI
- 6.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physical Anthropology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Pennsylvania State University
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Social Sciences › Arts and Humanities › Archeology › Paleopathology and ancient diseases
- Keywords
- ancient DNA, mitochondrial lineages, skeletal remains, matrilineal ancestry, male immigration, central Illinois, genetic variation
- MeSH terms
- Adult, Base Sequence, DNA, Mitochondrial, Female, Genetic Markers, Humans, Illinois, Indians, North American, Male, Molecular Sequence Data, Phylogeny, Genetic Variation, Polymerase Chain Reaction, Sequence Deletion, History, Medieval
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