The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis
Open accessAbstract
Objective: Cross‐sectional studies of optical coherence tomography (OCT) show that retinal nerve fiber layer (RNFL) thickness is reduced in multiple sclerosis (MS) and correlates with visual function. We determined how longitudinal changes in RNFL thickness relate to visual loss. We also examined patterns of RNFL thinning over time in MS eyes with and without a prior history of acute optic neuritis (ON). Methods: Patients underwent OCT measurement of RNFL thickness at baseline and at 6‐month intervals during a mean follow‐up of 18 months at 3 centers. Low‐contrast letter acuity (2.5%, 1.25% contrast) and visual acuity (VA) were assessed. Results: Among 299 patients (593 eyes) with ≥6 months follow‐up, eyes with visual loss showed greater RNFL thinning compared to eyes with stable vision (low‐contrast acuity, 2.5%: p < 0.001; VA: p = 0.005). RNFL thinning increased over time, with average losses of 2.9μm at 2 to 3 years and 6.1μm at 3 to 4.5 years (p < 0.001 vs 0.5–1‐year follow‐up interval). These patterns were observed for eyes with or without prior history of ON. Proportions of eyes with RNFL loss greater than test‐retest variability (≥6.6μm) increased from 11% at 0 to 1 year to 44% at 3 to 4.5 years (p < 0.001). Interpretation: Progressive RNFL thinning occurs as a function of time in some patients with MS, even in the absence of ON, and is associated with clinically significant visual loss. These findings are consistent with subclinical axonal loss in the anterior visual pathway in MS, and support the use of OCT and low‐contrast acuity as methods to evaluate the effectiveness of putative neuroprotection protocols. ANN NEUROL 2010;67:749–760
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Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
Polman, C. H., Reingold, S. C., Banwell, B., Clanet, M., Cohen, J. A., Filippi, M., Fujihara, K., Havrdova, E., Hutchinson, M., Kappos, L., et al. (2011) · Annals of Neurology · doi:10.1002/ana.22366 · Cited by 9,802
Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”
Polman, C. H., Reingold, S. C., Edan, G., Filippi, M., Hartung, H., Kappos, L., Lublin, F. D., Metz, L. M., McFarland, H. F., O'Connor, P. W., et al. (2005) · Annals of Neurology · doi:10.1002/ana.20703 · Cited by 5,017
Axonal transection in the lesions of multiple sclerosis
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Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS
Rudick, R. A., Fisher, E., Lee, J.-C., Simon, J., Jacobs, L., & the Multiple Sclerosis Collaborative Research Group (1999) · Neurology · doi:10.1212/wnl.53.8.1698 · Cited by 736
Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT
Budenz, D. L., Anderson, D. R., Varma, R., Schuman, J., Cantor, L., Savell, J., Greenfield, D. S., Patella, V. M., Quigley, H. A., & Tielsch, J. (2007) · Ophthalmology · doi:10.1016/j.ophtha.2006.08.046 · Cited by 684
Relation of Visual Function to Retinal Nerve Fiber Layer Thickness in Multiple Sclerosis
FISHER, J., JACOBS, D., MARKOWITZ, C., GALETTA, S., VOLPE, N., NANOSCHIAVI, M., BAIER, M., FROHMAN, E., WINSLOW, H., & FROHMAN, T. (2006) · Ophthalmology · doi:10.1016/j.ophtha.2005.10.040 · Cited by 658
Self-citationQuantifying axonal loss after optic neuritis with optical coherence tomography
Costello, F., Coupland, S., Hodge, W., Lorello, G. R., Koroluk, J., Pan, Y. I., Freedman, M. S., Zackon, D. H., & Kardon, R. H. (2006) · Annals of Neurology · doi:10.1002/ana.20851 · Cited by 610
Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis
Trip, S. A., Schlottmann, P. G., Jones, S. J., Altmann, D. R., Garway-Heath, D. F., Thompson, A. J., Plant, G. T., & Miller, D. H. (2005) · Annals of Neurology · doi:10.1002/ana.20575 · Cited by 509
Retinal nerve fiber layer is associated with brain atrophy in multiple sclerosis
Gordon-Lipkin, E., Chodkowski, B., Reich, D. S., Smith, S. A., Pulicken, M., Balcer, L. J., Frohman, E. M., Cutter, G., & Calabresi, P. A. (2007) · Neurology · doi:10.1212/01.wnl.0000295995.46586.ae · Cited by 419
Self-citationImaging outcomes for neuroprotection and repair in multiple sclerosis trials
Barkhof, F., Calabresi, P. A., Miller, D. H., & Reingold, S. C. (2009) · Nature Reviews Neurology · doi:10.1038/nrneurol.2009.41 · Cited by 378
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Yu-Wai-Man, P., Griffiths, P. G., & Chinnery, P. F. (2011) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2010.11.002 · Cited by 633
The OSCAR-IB Consensus Criteria for Retinal OCT Quality Assessment
Tewarie, P., Balk, L., Costello, F., Green, A., Martin, R., Schippling, S., & Petzold, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034823 · Cited by 627
Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis
Petzold, A., Balcer, L. J., Calabresi, P. A., Costello, F., Frohman, T. C., Frohman, E. M., Martinez-Lapiscina, E. H., Green, A. J., Kardon, R., Outteryck, O., et al. (2017) · The Lancet Neurology · doi:10.1016/s1474-4422(17)30278-8 · Cited by 585
Self-citationMicrocystic macular oedema in multiple sclerosis is associated with disease severity
Gelfand, J. M., Nolan, R., Schwartz, D. M., Graves, J., & Green, A. J. (2012) · Brain · doi:10.1093/brain/aws098 · Cited by 331
Ganglion Cell Loss in Relation to Visual Disability in Multiple Sclerosis
Walter, S. D., Ishikawa, H., Galetta, K. M., Sakai, R. E., Feller, D. J., Henderson, S. B., Wilson, J. A., Maguire, M. G., Galetta, S. L., Frohman, E., et al. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2011.11.032 · Cited by 294
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Metadata
- Authors
- Talman, L. S., Bisker, E. R., Sackel, D. J., Long, D. A., Galetta, K. M., Ratchford, J. N., Lile, D. J., Farrell, S. K., Loguidice, M. J., Remington, G., Conger, A., Frohman, T. C., Jacobs, D. A., Markowitz, C. E., Cutter, G. R., Ying, G., Dai, Y., Maguire, M. G., Galetta, S. L., Frohman, E. M., Calabresi, P. A., & Balcer, L. J.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2010-05-25
- Volume
- 67
- Issue
- 6
- Pages
- 749-760
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W1940014806
- Cited by
- 366
- References
- 44
- FWCI
- 21.92
- Type
- journal article
- Language
- en
- Open access
- green
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- Talman, L. S., Bisker, E. R., Sackel, D. J., Long, D. A., Galetta, K. M., Ratchford, J. N., Lile, D. J., Farrell, S. K., Loguidice, M. J., Remington, G., Conger, A., Frohman, T. C., Jacobs, D. A., Markowitz, C. E., Cutter, G. R., Ying, G., Dai, Y., Maguire, M. G., Galetta, S. L., . . . Balcer, L. J. (2010). Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis. Annals of Neurology. https://doi.org/10.1002/ana.22005
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