The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Dietary intakes of berries and flavonoids in relation to cognitive decline
Open accessAbstract
Objective: Berries are high in flavonoids, especially anthocyanidins, and improve cognition in experimental studies. We prospectively evaluated whether greater long‐term intakes of berries and flavonoids are associated with slower rates of cognitive decline in older women. Methods: Beginning in 1980, a semiquantitative food frequency questionnaire was administered every 4 years to Nurses' Health Study participants. In 1995–2001, we began measuring cognitive function in 16,010 participants, aged ≥70 years; follow‐up assessments were conducted twice, at 2‐year intervals. To ascertain long‐term diet, we averaged dietary variables from 1980 through the initial cognitive interview. Using multivariate‐adjusted, mixed linear regression, we estimated mean differences in slopes of cognitive decline by long‐term berry and flavonoid intakes. Results: Greater intakes of blueberries and strawberries were associated with slower rates of cognitive decline (eg, for a global score averaging all 6 cognitive tests, for blueberries: p‐trend = 0.014 and mean difference = 0.04, 95% confidence interval [CI] = 0.01–0.07, comparing extreme categories of intake; for strawberries: p‐trend = 0.022 and mean difference = 0.03, 95% CI = 0.00–0.06, comparing extreme categories of intake), after adjusting for multiple potential confounders. These effect estimates were equivalent to those we found for approximately 1.5 to 2.5 years of age in our cohort, indicating that berry intake appears to delay cognitive aging by up to 2.5 years. Additionally, in further supporting evidence, greater intakes of anthocyanidins and total flavonoids were associated with slower rates of cognitive decline (p‐trends = 0.015 and 0.053, respectively, for the global score). Interpretation: Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults. ANN NEUROL 2012
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Blueberry supplementation improves memory in older adults
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MIND diet associated with reduced incidence of Alzheimer's disease
Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Bennett, D. A., & Aggarwal, N. T. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.11.009 · Cited by 1,162
MIND diet slows cognitive decline with aging
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Low-grade inflammation, diet composition and health: current research evidence and its translation
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Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
Kalt, W., Cassidy, A., Howard, L. R., Krikorian, R., Stull, A. J., Tremblay, F., & Zamora-Ros, R. (2020) · Advances in Nutrition · doi:10.1093/advances/nmz065 · Cited by 659
Nutrition and prevention of cognitive impairment
Scarmeas, N., Anastasiou, C. A., & Yannakoulia, M. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30338-7 · Cited by 612
Metadata
- Authors
- Devore, E. E., Kang, J. H., Breteler, M. M. B., & Grodstein, F.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2012-04-26
- Volume
- 72
- Issue
- 1
- Pages
- 135-143
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2134920988
- Cited by
- 437
- References
- 28
- FWCI
- 13.48
- Type
- journal article
- Language
- en
- Open access
- bronze
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