MIND diet associated with reduced incidence of Alzheimer's disease
Open accessAbstract
Introduction: In a previous study, higher concordance to the MIND diet, a hybrid Mediterranean‐Dietary Approaches to Stop Hypertension diet, was associated with slower cognitive decline. In this study we related these three dietary patterns to incident Alzheimer's disease (AD). Methods: We investigated the diet‐AD relations in a prospective study of 923 participants, ages 58 to 98 years, followed on average 4.5 years. Diet was assessed by a semiquantitative food frequency questionnaire. Results: In adjusted proportional hazards models, the second (hazards ratio or HR = 0.65, 95% confidence interval or CI 0.44, 0.98) and highest tertiles (HR = 0.47, 95% CI 0.26, 0.76) of MIND diet scores had lower rates of AD versus tertile 1, whereas only the third tertiles of the DASH (HR = 0.61, 95% CI 0.38, 0.97) and Mediterranean (HR = 0.46, 95% CI 0.26, 0.79) diets were associated with lower AD rates. Discussion: High adherence to all three diets may reduce AD risk. Moderate adherence to the MIND diet may also decrease AD risk.
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Emerging evidence suggests that consuming a heart-healthy diet may be associated with reduced dementia risk.
“In addition to physical activity, emerging evidence suggests that consuming a heart-healthy diet may be associated with reduced dementia risk.129-134”
From 2023 Alzheimer's disease facts and figures (2023) · cites this paper as [132]
Eating a heart-healthy diet and increasing physical activity could delay the onset of AD.
“Collectively, this suggests that eating a heart-healthy diet [172,173,174,175,176] and increasing physical activity [177,178,179,180] could delay the onset of AD.”
From Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease (2020) · cites this paper as [175]
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- Authors
- Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Bennett, D. A., & Aggarwal, N. T.
- Affiliations
- Rush University Medical Center (US)
- Harvard University (US)
- Corresponding author
- Morris, Martha Clare
- ORCID
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2015-02-11
- Volume
- 11
- Issue
- 9
- Pages
- 1007-1014
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- PMC
- PMC4532650
- OpenAlex
- W1990713904
- Cited by
- 1,162
- References
- 35
- Citations by year
- 2026: 131 · 2025: 166 · 2024: 136 · 2023: 124 · 2022: 124 · 2021: 133 · 2020: 147 · 2019: 68 · 2018: 64 · 2017: 39 · 2016: 24 · 2015: 5
- FWCI
- 47.19
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Alzheimer s & Dementia (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- Funders
- National Institute on Aging (R01AG031553, R01AG17917)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Keywords
- MIND diet, Alzheimer's disease
- MeSH terms
- Aged, 80 and over, Alzheimer Disease, Chicago, Cognition Disorders, Female, Humans, Male, Patient Compliance, Prospective Studies, Incidence, Proportional Hazards Models, Survival Analysis, Disease Progression, Diet, Mediterranean
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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