The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Validation of clinical diagnostic criteria for Alzheimer's disease
Abstract
Clinical investigations of Alzheimer's disease (AD) have been limited by diagnostic inaccuracy. We employed explicit clinical inclusion and exclusion criteria to identify subjects with senile dementia of the Alzheimer type (SDAT). In a consecutive series of 26 postmortem examinations from this sample, AD was histologically verified in all subjects and was the primary dementing illness. Seventeen of the 26 SDAT subjects had been diagnosed when only mildly demented. Two control subjects were examined neuropathologically; AD was absent in both. We conclude that research clinical diagnostic criteria for SDAT, even in its mild stage, are valid.
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A New Clinical Scale for the Staging of Dementia
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Research works printed but not linked: 3
- Morris JC, 1987, Validation of clinical diagnostic criteria in senile dementia of the Alzheimer type, Ann Neurol, 22, 122
- Morris JC, 1987, Parkinsonism in senile dementia of the Alzheimer type, 499
- Joachim CL, 1986, Autopsy neuropathology in 76 cases of clinically diagnosed Alzheimer's disease, Neurology, 36, 226
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Items 101–104 of 104
McKeel, D. W., Price, J. L., Miller, J. P., Grant, E. A., Xiong, C., Berg, L., & Morris, J. C. (2004) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/63.10.1028 · Cited by 68
Self-citationSerum α-tocopherol, concurrent and past vitamin E intake, and mild cognitive impairment
Dunn, J. E., Weintraub, S., Stoddard, A. M., & Banks, S. (2007) · Neurology · doi:10.1212/01.wnl.0000255940.13116.86 · Cited by 25
Use of Genetic Variation as Biomarkers for Alzheimer's Disease
Reitz, C., & Mayeux, R. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04945.x · Cited by 24
Metadata
- Authors
- Morris, J. C., McKeel, D. W., Fulling, K., Torack, R. M., & Berg, L.
- Affiliations
- Washington University in St. Louis (US)
- Corresponding author
- Morris, John C.
- ORCID
- Morris, John C.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1988-07
- Volume
- 24
- Issue
- 1
- Pages
- 17-22
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2055629766
- Cited by
- 362
- References
- 31
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 2 · 2023: 6 · 2022: 5 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 6 · 2017: 2 · 2015: 2 · 2014: 6 · 2013: 8 · 2012: 7
- FWCI
- 19.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (AG03991, AG 05681)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Keywords
- Alzheimer's disease, senile dementia of the Alzheimer type, clinical criteria, diagnostic accuracy, mild dementia, postmortem neuropathology, histopathological confirmation, underdiagnosis of dementia
- MeSH terms
- Aged, Aged, 80 and over, Alzheimer Disease, Brain, Cerebral Infarction, Diagnosis, Differential, Female, Humans, Male, Neuropsychological Tests
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