Isoprostanes: Potential Markers of Oxidant Stress in Atherothrombotic Disease
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Abstract Isoprostanes are emerging as a new class of biologically active products of arachidonic acid metabolism of potential relevance to human vascular disease. Their formation in vivo seems to reflect primarily, if not exclusively, a nonenzymatic process of lipid peroxidation. Enhanced urinary excretion of 8-iso-PGF 2α has been described in association with cardiac reperfusion injury and with cardiovascular risk factors, including cigarette smoking, diabetes mellitus, and hypercholesterolemia. Besides providing a likely noninvasive index of lipid peroxidation in these settings, measurements of specific F 2 isoprostanes in urine may provide a sensitive biochemical end point for dose-finding studies of natural and synthetic inhibitors of lipid peroxidation. Although the biological effects of 8-iso-PGF 2α in vitro suggest that it and other isoeicosanoids may modulate the functional consequences of lipid peroxidation, evidence that this is likely in vivo remains inadequate at this time.
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F2-isoprostanes are generated from arachidonic acid through nonenzymatic free radical-catalyzed lipid peroxidation and are an established marker of oxidative stress.
“F2-isoprostanes are generated from arachidonic acid through a process of nonenzymatic free radical-catalyzed lipid peroxidation, thus representing an established marker of oxidative stress.33”
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OLSSON, A. G., McMurray, J. J. V., Thorgeirsson, G., Spaulding, C. M., Slattery, J., Pyörälà, K., Færgeman, O., Wright, R. S., Berg, K. M., Wilhelmsen, L., et al. (1994) · The Lancet · Cited by 8,467 · see citing works
Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia
Shepherd, J., Cobbe, S. M., Ford, I., Isles, C. G., Lorimer, A. R., Macfarlane, P. W., McKillop, J. H., & Packard, C. J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199511163332001 · Cited by 7,449 · see citing works
Epstein, F. H., Steinberg, D. I., Parthasarathy, S., Carew, T. E., Khoo, J. C., & Witztum, J. L. (1989) · New England Journal of Medicine · doi:10.1056/nejm198904063201407 · Cited by 6,425 · see citing works
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.
Hámberg, M., Svensson, J., & Samuelsson, B. O. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.8.2994 · Cited by 3,064 · see citing works
Role of oxidized low density lipoprotein in atherogenesis.
Witztum, J. L., & Steinberg, D. H. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115499 · Cited by 2,682 · see citing works
Stephens, N. G., Parsons, A., Brown, M. J., Schofield, P. M., Kelly, F., Cheeseman, K., & Mitchinson, M. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90866-1 · Cited by 2,148 · see citing works
Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2
Smith, W. L., Garavito, R. M., & DeWitt, D. L. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.52.33157 · Cited by 1,973 · see citing works
Morrow, J. D., Hill, K. E., Burk, R. F., Nammour, T., Badr, K. F., & Roberts, L. J. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.23.9383 · Cited by 1,898 · see citing works
Tuomilehto, J., Vidgrén, G., Toivanen, L., Tuomilehto‐Wolf, E., Kohtamäki, K., Stengård, J., Zimmet, P., Mackay, I. R., Rowley, M. J., & Koskela, P. U. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92521-6 · Cited by 1,691 · see citing works
The role of oxidized lipoproteins in atherogenesis
Berliner, J. A., & Heinecke, J. W. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02173-6 · Cited by 1,365 · see citing works
Morrow, J. D., Frei, B. B., Longmire, A. W., Gaziano, J. M., Lynch, S. M., Shyr, Y., Strauss, W., Oates, J. A., & Roberts, L. J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199505043321804 · Cited by 1,340 · see citing works
The measurement and mechanism of lipid peroxidation in biological systems
Gutteridge, J. M. C., & Halliwell, B. B. (1990) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(90)90206-q · Cited by 1,292 · see citing works
Brown, B., Zhao, X., Sacco, D., & Albers, J. (1993) · Circulation · doi:10.1161/01.cir.87.6.1781 · Cited by 886 · see citing works
The Yin and Yang of Oxidation in the Development of the Fatty Streak
Navab, M., Berliner, J. A., Watson, A. D., Hama, S. Y., Territo, M., Lusis, A. J., Shih, D. M., Lenten, B. J. V., Frank, J. S., Demer, L. L., et al. (1996) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.16.7.831 · Cited by 699 · see citing works
Bolli, R., Patel, B. S., Jeroudi, M. O., Lai, E. K., & McCay, P. B. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113621 · Cited by 685 · see citing works
Modulation of Oxidant Stress In Vivo in Chronic Cigarette Smokers
Reilly, M., Delanty, N., Lawson, J. A., & FitzGerald, G. A. (1996) · Circulation · doi:10.1161/01.cir.94.1.19 · Cited by 612 · see citing works
Self-citationBolli, R., Jeroudi, M. O., Patel, B. S., Aruoma, O. I., Halliwell, B. B., Lai, E. K., & McCay, P. B. (1989) · Circulation Research · doi:10.1161/01.res.65.3.607 · Cited by 579 · see citing works
Bolli, R. (1992) · Circulation · doi:10.1161/01.cir.86.6.1671 · Cited by 529 · see citing works
Takahashi, K., Nammour, T., Fukunaga, M., Ebert, J., Morrow, J. D., Roberts, L. J., Hoover, R. L., & Badr, K. F. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115826 · Cited by 510 · see citing works
Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues.
Kloner, R. A., Przyklenk, K., & Whittaker, P. (1989) · Circulation · doi:10.1161/01.cir.80.5.1115 · Cited by 504 · see citing works
Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease.
FitzGerald, G. A., Pedersen, A. K., & Patrono, C. (1983) · Circulation · doi:10.1161/01.cir.67.6.1174 · Cited by 472 · see citing works
Self-citationJha, P., Flather, M., Lonn, E., Farkouh, M., & Yusuf, S. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-11-199512010-00009 · Cited by 399 · see citing works
Gopaul, N. K., Änggård, E. E., Mallet, A. I., Betteridge, D. J., Wolff, S. P., & Nourooz-Zadeh, J. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00649-t · Cited by 390 · see citing works
Localization of distinct F2-isoprostanes in human atherosclerotic lesions.
Praticò, D., Iuliano, L., Mauriello, A., Spagnoli, L. G., Lawson, J. A., Rokach, J., Maclouf, J., Violi, F., & FitzGerald, G. A. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119735 · Cited by 344 · see citing works
Self-citationImmunological characterization of urinary 8-epi-prostaglandin F2 alpha excretion in man.
Wang, Z., Ciabattoni, G., Créminon, C., Lawson, J. A., FitzGerald, G. A., Patrono, C., & Maclouf, J. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12087-9 · Cited by 341 · see citing works
Self-citationAcute myocardial dysfunction and recovery: A common occurrence after coronary bypass surgery
Breisblatt, W. M., Stein, K. L., Wolfe, C. J., Follansbee, W. P., Capozzi, J., Armitage, J. M., & Hardesty, R. L. (1990) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(10)80011-7 · Cited by 316 · see citing works
α-Tocopherol Inhibits Aggregation of Human Platelets by a Protein Kinase C–Dependent Mechanism
Freedman, J. E., Farhat, J. H., Loscalzo, J., & Keaney, J. F. (1996) · Circulation · doi:10.1161/01.cir.94.10.2434 · Cited by 311 · see citing works
Morrow, J. D., Minton, T. A., Mukundan, C. R., Campbell, M., Zackert, W. E., Daniel, V. C., Badr, K. F., Blair, I. A., & Roberts, L. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41781-9 · Cited by 299 · see citing works
Tsai, E. C., Hirsch, I. B., Brunzell, J. D., & Chait, A. (1994) · Diabetes · doi:10.2337/diab.43.8.1010 · Cited by 281 · see citing works
8-Epi PGF2αGeneration During Coronary Reperfusion
Delanty, N., Reilly, M. P., Praticò, D., Lawson, J. A., McCarthy, J. F., Wood, A., Ohnishi, S. T., Fitzgerald, D. J., & FitzGerald, G. A. (1997) · Circulation · doi:10.1161/01.cir.95.11.2492 · Cited by 267 · see citing works
Self-citationCylooxygenase-dependent Formation of the Isoprostane, 8-Epi Prostaglandin F2α
Praticò, D., Lawson, J. A., & FitzGerald, G. A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.17.9800 · Cited by 266 · see citing works
Self-citationEvidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells
Fukunaga, M., Makita, N., Roberts, L. J., Morrow, J. D., Takahashi, K., & Badr, K. F. (1993) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1993.264.6.c1619 · Cited by 254 · see citing works
Lynch, S. M., Morrow, J. D., Roberts, L. J., & Frei, B. B. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117107 · Cited by 236 · see citing works
Morrow, J. D., Minton, T. A., & Roberts, L. J. (1992) · Prostaglandins · doi:10.1016/0090-6980(92)90077-7 · Cited by 215 · see citing works
Beneficial actions of superoxide dismutase and catalase in stunned myocardium of dogs
Gross, G. J., Farber, N. E., Hardman, H. F., & Warltier, D. C. (1986) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1986.250.3.h372 · Cited by 206 · see citing works
Praticò, D., Smyth, E. M., Violi, F., & FitzGerald, G. A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.25.14916 · Cited by 204 · see citing works
Self-citationGeneration of 8-Epiprostaglandin F by Human Monocytes
Praticò, D., & FitzGerald, G. A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.15.8919 · Cited by 188 · see citing works
Self-citationIncreased thromboxane biosynthesis in type IIa hypercholesterolemia.
Davı̀, G., Averna, M. R., Catalano, I., Barbagallo, C. M., Ganci, A., Notarbartolo, A., Ciabattoni, G., & Patrono, C. (1992) · Circulation · doi:10.1161/01.cir.85.5.1792 · Cited by 166 · see citing works
Self-citationAntioxidant Vitamins and Cardiovascular Disease
Buring, J. E., & Gaziano, J. M. (1997) · Humana Press eBooks · doi:10.1007/978-1-4757-6242-6_9 · Cited by 162 · see citing works
Kinsella, B. T., O’Mahony, D. J., & FitzGerald, G. A. (1997) · PubMed · Cited by 160 · see citing works
Self-citationAwad, J. A., Morrow, J. D., Takahashi, K., & Roberts, L. J. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53593-6 · Cited by 158 · see citing works
Enhanced in vitro oxidation of plasma lipoproteins derived from hypercholesterolemic patients
Lavy, A., Brook, G. J., Dankner, G., Amotz, A. B., & Aviram, M. (1991) · Metabolism · doi:10.1016/0026-0495(91)90005-h · Cited by 156 · see citing works
Roberts, L. J., Moore, K. P., Zackert, W. E., Oates, J. A., & Morrow, J. D. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.34.20617 · Cited by 154 · see citing works
Assay of Malondialdehyde in Biological Fluids by Gas Chromatography-Mass Spectrometry
Yeo, H.-R., Helbock, H. J., Chyu, D. W., & Ames, B. N. (1994) · Analytical Biochemistry · doi:10.1006/abio.1994.1355 · Cited by 148 · see citing works
O'Connor, D. E., Mihelich, E. D., & Coleman, M. C. (1984) · Journal of the American Chemical Society · doi:10.1021/ja00324a028 · Cited by 124 · see citing works
Functional Characterization of the Ocular Prostaglandin F2α (PGF2α) Receptor
Kunapuli, P., Lawson, J. A., Rokach, J., & FitzGerald, G. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.43.27147 · Cited by 102 · see citing works
Self-citationIsoleukotrienes are biologically active free radical products of lipid peroxidation
Harrison, K. A., & Murphy, R. C. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.29.17273 · Cited by 98 · see citing works
Lipid peroxidation associated with successful thrombolysis
Ranjadayalan, K. (1990) · The Lancet · doi:10.1016/0140-6736(90)90866-4 · Cited by 96 · see citing works
Lipoprotein Oxidation and Lipoprotein-lnduced Cell Injury in Diabetes
Chisolm, G. M., Irwin, K. C., & Penn, M. S. (1992) · Diabetes · doi:10.2337/diab.41.2.s61 · Cited by 89 · see citing works
Evidence for episodic platelet activation in acute ischemic stroke.
van Kooten, F., Ciabattoni, G., Patrono, C., Schmitz, P. I. M., van Gijn, J., & Koudstaal, P. J. (1994) · Stroke · doi:10.1161/01.str.25.2.278 · Cited by 83 · see citing works
Self-citationPanara, M. R., Greco, A., Santini, G., Sciulli, M. G., Rotondo, M. T., Padovano, R., di Giamberardino, M., Cipollone, F., Cuccurullo, F., Patrono, C., et al. (1995) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1995.tb15091.x · Cited by 82 · see citing works
Self-citationAssessment of myocardial oxidative stress in patients after myocardial revascularization
Ferreira, R., Llesuy, S., Milei, J., Scordo, D., Hourquebie, H., Molteni, L., de Palma, C., & Boveris, A. (1988) · American Heart Journal · doi:10.1016/0002-8703(88)90475-9 · Cited by 80 · see citing works
Patrignani, P., Santini, G., Panara, M. R., Sciulli, M. G., Greco, A., Rotondo, M. T., di Giamberardino, M., Maclouf, J., Ciabattoni, G., & Patrono, C. (1996) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1996.tb15535.x · Cited by 75 · see citing works
Self-citationHuman globin gene analysis for a patient with beta-o/delta beta-thalassemia.
Ottolenghi, S., Lanyon, W. G., Williamson, R., Weatherall, D. J., Clegg, J. B., & Pitcher, C. S. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.6.2294 · Cited by 69 · see citing works
Cyclooxygenase‐Dependent Formation of the Isoprostane 8‐EPI Prostaglandin F2αa
Praticò, D., Lawson, J. A., & FitzGerald, G. A. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb52730.x · Cited by 66 · see citing works
Self-citationTotal synthesis of a novel isoprostane IPF2α-I and its identification in biological fluids
Adiyaman, M., Lawson, J. A., Hwang, S., Khanapure, S. P., FitzGerald, G. A., & Rokach, J. (1996) · Tetrahedron Letters · doi:10.1016/0040-4039(96)00973-2 · Cited by 55 · see citing works
Self-citationIs Pentane a Normal Constituent of Human Breath?
Cailleux, A., & Allain, P. (1993) · Free Radical Research Communications · doi:10.3109/10715769309147499 · Cited by 47 · see citing works
Thromboxane biosynthesis and metabolism in relation to cardiovascular risk factors
Patrono, C., Davı̀, G., & Ciabattoni, G. (1992) · Trends in Cardiovascular Medicine · doi:10.1016/1050-1738(92)90039-u · Cited by 36 · see citing works
Self-citationCominacini, L., Pastorino, A. M., Garbin, U., Campagnola, M., de Santis, A., Davoli, A., Faccini, G., Bertozzo, L., Pasini, F., & Af, P. (1994) · PubMed · Cited by 27 · see citing works
Free radical activity and left ventricular function after thrombolysis for acute infarction.
Davies, S., Ranjadayalan, K., Wickens, D. G., Dormandy, T. L., Umachandran, V., & Timmis, A. (1993) · Heart · doi:10.1136/hrt.69.2.114 · Cited by 21 · see citing works
Coronary heart disease and vitamin E
Riemersma, R. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90861-2 · Cited by 17 · see citing works
Flagged first, then by citations
Research works printed but not linked: 9
- O'Connor DE, Mihelic ED, Coleman MC. Stereochemical course of the auto-oxidative cyclization of lipid hydroperoxides to prosta- glandin-like bicyclo endoperoxides. J Am Chem Soc. 1984;106: 3577-3584.
- Kinsella BT, O'Mahony DJ, FitzGerald GA. The human thromboxane A2 receptor a isoform (TPa) functionally couples to the G-proteins G q and G n in vivo and is activated by the iso- prostane 8-epi prostaglandin F 2 ". J Pharmacol Exp Ther. In press.
- Kunapuli P, Lawson JA, Rokach JA, FitzGerald GA. Functional characterization of the ocular PGF 2a receptor: activation by the isoprostane 12-epi-PGF 2a . J Biol Chem. 1997;272:27147-27154.
- Reilly MP, Delanty N, O'Callaghan P, Crean P, Roy L, FitzGerald GA. Increased generation of the F 2 isoprostanes, IPF 2o -l and 8-iso-PGF 2 " in acute coronary angioplasty: evidence for oxidant stress during coronary reperfusion in humans. Circulation. In press.
- Ciabattoni G, Patrono C, Van Kooten F, Koudstaal PJ. Disso- ciation of platelet activation and lipid peroxidation in acute ische- mic stroke. J Invest Med. 1995;43:292A. Abstract.
- Catella-Lawson F, Kapoor S, Pratico D, Braunstein SN, Caraballo V, FitzGerald GA. Oxidative stress and diabetes mellitus. J Invest Med. 1996;44:223A. Abstract.
- Ciabattoni G, Consoli A, Vitacolonna E, Mezzetti A, Santarone S, Pennese E, Falco A, Davi G, Patrono C. In vivo formation of 8-epi-prostaglandin F 2o in diabetes mellitus: effects of tight meta- bolic control and vitamin E supplementation. Thromb Haemost. In press. Abstract.
- Davi G, Alessandrini P, Mezzetti A, Minotti G, Bucciarelli T, Constantini F, Cipallone F, Bittolo Bon G, Ciabattoni G, Patrono C. In vivo formation of 8-epi-PGF 2o is increased in hypercholester- olemia. Arterioscler Thromb Vase Biol. In press.
- Palinski W, Witztum JL. Oxidative stress and diabetes mellitus. In: Schwartz CJ, Born GVR, eds. New Horizons in Diabetes Mellitus and Cardiovascular Disease. Rapid Science Publishers; 1996:81-93.
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Montuschi, P., Barnes, P. J., & Roberts, L. J. (2004) · The FASEB Journal · doi:10.1096/fj.04-2330rev · Cited by 747 · see citing works
Davı̀, G., Ciabattoni, G., Consoli, A., Mezzetti, A., Falco, A., Santarone, S., Pennese, E., Vitacolonna, E., Bucciarelli, T., Costantini, F., et al. (1999) · Circulation · doi:10.1161/01.cir.99.2.224 · Cited by 742 · see citing works
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Aspirin resistance: definition, mechanisms and clinical read-outs
Patrono, C. (2003) · Journal of Thrombosis and Haemostasis · doi:10.1046/j.1538-7836.2003.00284.x · Cited by 298 · see citing works
Self-citationKullisaar, T., Songisepp, E., Mikelsaar, M., Zilmer, K., Vihalemm, T., & Zilmer, M. (2003) · British Journal Of Nutrition · doi:10.1079/bjn2003896 · Cited by 295 · see citing works
Risérus, U., Basu, S., Jovinge, S., Fredrikson, G. N., Ärnlöv, J., & Vessby, B. (2002) · Circulation · doi:10.1161/01.cir.0000033589.15413.48 · Cited by 292 · see citing works
Human health implications of environmental contaminants in Arctic Canada: A review
Oostdam, J. V., Donaldson, S. G., Feeley, M., Arnold, D., Ayotte, P., Bondy, G. S., Chan, H. M., Dewailly, É., Furgal, C. M., Kuhnlein, H. V., et al. (2005) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2005.03.034 · Cited by 271 · see citing works
Increased Formation of Distinct F2Isoprostanes in Hypercholesterolemia
Reilly, M. P., Praticò, D., Delanty, N., DiMinno, G., Tremoli, E., Rader, D. J., Kapoor, S. C., Rokach, J., Lawson, J. A., & FitzGerald, G. A. (1998) · Circulation · doi:10.1161/01.cir.98.25.2822 · Cited by 271 · see citing works
Self-citation8-Isoprostane as a Biomarker of Oxidative Stress in Interstitial Lung Diseases
Montuschi, P., TONI, G. C., Paredi, P., Pantelidis, P., du Bois, R. M., Kharitonov, S. A., & Barnes, P. J. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.5.9803102 · Cited by 267 · see citing works
Uric acid reduces exercise-induced oxidative stress in healthy adults
Waring, W. S., CONVERY, A., Mishra, V., Shenkin, A., Webb, D. J., & Maxwell, S. R. J. (2003) · Clinical Science · doi:10.1042/cs20030149 · Cited by 257 · see citing works
Praticò, D., Basili, S., Vieri, M., Cordova, C., Violi, F., & FitzGerald, G. A. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.6.9709066 · Cited by 254 · see citing works
Self-citationAlcohol-induced generation of lipid peroxidation products in humans
Meagher, E. A., Barry, Ó. P., Burke, A., Lucey, M. R., Lawson, J. A., Rokach, J., & FitzGerald, G. A. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5584 · Cited by 251 · see citing works
Self-citationRisérus, U., Vessby, B. O., Ärnlöv, J., & Basu, S. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.2.279 · Cited by 243 · see citing works
Bioavailability of lutein from vegetables is 5 times higher than that of β-carotene
Hof, K. H. V. H., Brouwer, I. A., West, C. E., Haddeman, E., Steegers‐Theunissen, R. P. M., van Dusseldorp, M., Weststrate, J. A., Eskes, T. K. A. B., & HAUTVAST, J. G. A. J. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn.70.2.261 · Cited by 243 · see citing works
Cayatte, A. J., Du, Y., Oliver-Krasinski, J. M., Lavielle, G., Verbeuren, T. J., & Cohen, R. A. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.7.1724 · Cited by 237 · see citing works
Roberts, C. K., Won, D., Pruthi, S., Kurtovic, S., Sindhu, R. K., Vaziri, N. D., & Barnard, R. J. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01292.2005 · Cited by 232 · see citing works
Oxidant Stress and Aspirin-Insensitive Thromboxane Biosynthesis in Severe Unstable Angina
Cipollone, F., Ciabattoni, G., Patrignani, P., Pasquale, M., Gregorio, D. D., Bucciarelli, T., Davı̀, G., Cuccurullo, F., & Patrono, C. (2000) · Circulation · doi:10.1161/01.cir.102.9.1007 · Cited by 225 · see citing works
Self-citationPascale, S., Petrucci, G., Dragani, A., Habib, A., Zaccardi, F., Pagliaccia, F., Pocaterra, D., Ragazzoni∘, E., Rolandi, G., Rocca, B., et al. (2012) · Blood · doi:10.1182/blood-2011-06-359224 · Cited by 219 · see citing works
Self-citationIPF 2α -I: An index of lipid peroxidation in humans
Praticò, D., Barry, Ó. P., Lawson, J. A., Adiyaman, M., Hwang, S., Khanapure, S. P., Iuliano, L., Rokach, J., & FitzGerald, G. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.3449 · Cited by 219 · see citing works
Self-citationMori, T. A., Croft, K. D., Puddey, I. B., & Beilin, L. J. (1999) · Analytical Biochemistry · doi:10.1006/abio.1998.3037 · Cited by 214 · see citing works
Insulin Resistance and Type 2 Diabetes in High-Fat–Fed Mice Are Linked to High Glycotoxin Intake
Sandu, O. A., Song, K., Cai, W., Zheng, F., Uribarri, J., & Vlassara, H. (2005) · Diabetes · doi:10.2337/diabetes.54.8.2314 · Cited by 213 · see citing works
Minuz, P., Patrignani, P., Gaino, S., Degan, M., Menapace, L., Tommasoli, R., Seta, F., Capone, M. L., Tacconelli, S., Palatresi, S., et al. (2002) · Circulation · doi:10.1161/01.cir.0000039528.49161.e9 · Cited by 211 · see citing works
Self-citationJahn, U., Galano, J., & Durand, T. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200705122 · Cited by 206 · see citing works
Enhanced In Vivo Lipid Peroxidation at Elevated Plasma Total Homocysteine Levels
Voutilainen, S., Morrow, J. D., Roberts, L. J., Alfthan, G., Alho, H., Nyyssönen, K., & Salonen, J. T. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.5.1263 · Cited by 205 · see citing works
Polyphenols synergistically inhibit oxidative stress in subjects given red and white wine
Pignatelli, P., Ghiselli, A., Buchetti, B., Carnevale, R., Natella, F., Germanò, G., Fimognari, F., Santo, S. D., Lenti, L., & Violi, F. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.10.025 · Cited by 201 · see citing works
Retinol Binding Protein-4 Levels and Clinical Features of Type 2 Diabetes Patients
Takebayashi, K., Suetsugu, M., Wakabayashi, S., Aso, Y., & Inukai, T. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1249 · Cited by 198 · see citing works
Olive Phenol Hydroxytyrosol Prevents Passive Smoking–Induced Oxidative Stress
Visioli, F., Galli, C., Plasmati, E., Viappiani, S., Hernandez, A., Colombo, C., & Sala, A. (2000) · Circulation · doi:10.1161/01.cir.102.18.2169 · Cited by 192 · see citing works
Audoly, L., Rocca, B., Fabre, J., Koller, B. H., Thomas, D. W., Loeb, A. L., Coffman, T. M., & FitzGerald, G. A. (2000) · Circulation · doi:10.1161/01.cir.101.24.2833 · Cited by 192 · see citing works
Self-citationWang, Y., Chun, O. K., & Song, W. O. (2013) · Nutrients · doi:10.3390/nu5082969 · Cited by 191 · see citing works
The impact of moderate wine consumption on health
Artero, A., Artero, A., Tarín, J. J., & Cano, A. (2014) · Maturitas · doi:10.1016/j.maturitas.2014.09.007 · Cited by 188 · see citing works
Ziegler, D., Sohr, C., & Nourooz‐Zadeh, J. (2004) · Diabetes Care · doi:10.2337/diacare.27.9.2178 · Cited by 182 · see citing works
Atteritano, M., Marini, H. R., Minutoli, L., Polito, F., Bitto, A., Altavilla, D., Mazzaferro, S., D’Anna, R., Cannata, M. L., Gaudio, A., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2295 · Cited by 176 · see citing works
Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes
Bitar, M. S., Wahid, S., Mustafa, S., Al‐Saleh, E., Dhaunsi, G. S., & Al‐Mulla, F. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.01.014 · Cited by 174 · see citing works
Cambonie, G., Comte, B., Yzydorczyk, C., Ntimbane, T., Germain, N., Lê, N. L. O., Pladys, P., Gauthier, C., Lahaie, I., Abran, D., et al. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00227.2006 · Cited by 171 · see citing works
Proudfoot, J. M., Barden, A. E., Mori, T. A., Burke, V., Croft, K. D., Beilin, L. J., & Puddey, I. B. (1999) · Analytical Biochemistry · doi:10.1006/abio.1999.4187 · Cited by 175 · see citing works
Takebayashi, K., Suetsugu, M., Wakabayashi, S., Aso, Y., & Inukai, T. (2007) · Metabolism · doi:10.1016/j.metabol.2006.12.001 · Cited by 174 · see citing works
Marchioli, R., Schweiger, C., Levantesi, G., Tavazzi, L., & Valagussa, F. (2001) · Lipids · doi:10.1007/s11745-001-0683-y · Cited by 173 · see citing works
Mallat, Z., Nakamura, T., Ohan, J., Lesèche, G., Tedgui, A., Maclouf, J., & Murphy, R. C. (1999) · Journal of Clinical Investigation · doi:10.1172/jci3985 · Cited by 172 · see citing works
Oxidized phospholipids and isoprostanes in atherosclerosis
Witztum, J. L., & Berliner, J. A. (1998) · Current Opinion in Lipidology · doi:10.1097/00041433-199810000-00008 · Cited by 170 · see citing works
Wilson, S. H., Simari, R. D., Best, P. J. M., Peterson, T. E., Lerman, L. O., Aviram, M., Nath, K. A., Holmes, D. R., & Lerman, A. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.21.1.122 · Cited by 166 · see citing works
F2-isoprostanes: sensitive and specific non-invasive indices of lipid peroxidation in vivo
Praticò, D. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(99)00257-9 · Cited by 165 · see citing works
Li, H., Lawson, J. A., Reilly, M. P., Adiyaman, M., Hwang, S., Rokach, J., & FitzGerald, G. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13381 · Cited by 161 · see citing works
Self-citationLin, C., Chang, C.-F., Lai, M.-Y., Chen, T.-W., Lee, P.-C., & Yang, W.-C. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006050534 · Cited by 161 · see citing works
Oxidative Stress and Cell Membranes in the Pathogenesis of Alzheimer's Disease
Axelsen, P. H., Komatsu, H., & Murray, I. V. J. (2011) · Physiology · doi:10.1152/physiol.00024.2010 · Cited by 158 · see citing works
Vassalle, C., Petrozzi, L., Botto, N., Andreassi, M. G., & Zucchelli, G. C. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01373.x · Cited by 156 · see citing works
Protective activity of tomato products on in vivo markers of lipid oxidation
Visioli, F., Riso, P., Grande, S., Galli, C., & Porrini, M. (2003) · European Journal of Nutrition · doi:10.1007/s00394-003-0415-5 · Cited by 155 · see citing works
Morrow, J. D., Zackert, W. E., Yang, J. P., Kurhts, E. H., Callewaert, D. M., Dworski, R., Kanai, K., Taber, D. F., Moore, K. P., Oates, J. A., et al. (1999) · Analytical Biochemistry · doi:10.1006/abio.1999.4008 · Cited by 153 · see citing works
Faraday, N. R., Yanek, L. R., Mathias, R. A., Herrera-Galeano, J. E., Vaidya, D. M., Moy, T. F., Fallin, M. D., Wilson, A. F., Bray, P. F., Becker, L. C., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.667584 · Cited by 152 · see citing works
Enhanced Lipid Peroxidation and Platelet Activation in the Early Phase of Type 1 Diabetes Mellitus
Davı̀, G., Chiarelli, F., Santilli, F., Pomilio, M., Vigneri, S., Falco, A., Basili, S., Ciabattoni, G., & Patrono, C. (2003) · Circulation · doi:10.1161/01.cir.0000074205.17807.d0 · Cited by 143 · see citing works
Self-citationOxidative stress in chronic vascular disease: From prediction to prevention
Santilli, F., D’Ardes, D., & Davı̀, G. (2015) · Vascular Pharmacology · doi:10.1016/j.vph.2015.09.003 · Cited by 140 · see citing works
DiMarco, T., & Giulivi, C. (2006) · Mass Spectrometry Reviews · doi:10.1002/mas.20109 · Cited by 140 · see citing works
Heinecke, J. W. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.10.1113 · Cited by 140 · see citing works
Is the anti-inflammatory effect of regular exercise responsible for reduced cardiovascular disease?
Wilund, K. R. (2007) · Clinical Science · doi:10.1042/cs20060368 · Cited by 138 · see citing works
Platelet dysfunction in central obesity
Anfossi, G., Russo, I., & Trovati, M. (2009) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2009.01.006 · Cited by 137 · see citing works
Sakata, R., Nakamura, T., Torimura, T., Ueno, T., & Sata, M. (2013) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2013.1503 · Cited by 134 · see citing works
Hereditary Deficiency of gp91 phox Is Associated With Enhanced Arterial Dilatation
Violi, F., Sanguigni, V., Carnevale, R., Plebani, A., Rossi, P., Finocchi, A., Pignata, C., Mattia, D. D., Martire, B., Pietrogrande, M. C., et al. (2009) · Circulation · doi:10.1161/circulationaha.109.877191 · Cited by 133 · see citing works
Oxidative Stress and Platelet Activation in Homozygous Homocystinuria
Davı̀, G., Minno, G. D., Coppola, A., Andria, G., Cerbone, A. M., Madonna, P., Tufano, A., Falco, A., Marchesani, P., Ciabattoni, G., et al. (2001) · Circulation · doi:10.1161/hc3501.095287 · Cited by 133 · see citing works
Self-citationMarchioli, R. (1999) · Pharmacological Research · doi:10.1006/phrs.1999.0480 · Cited by 130 · see citing works
Increased oxidative damage to all DNA bases in patients with type II diabetes mellitus
Rehman, A., Nourooz‐Zadeh, J., Möller, W., Tritschler, H., Pereira, P., & Halliwell, B. B. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00339-7 · Cited by 127 · see citing works
Ky, B., Burke, A., Tsimikas, S., Wolfe, M. L., Tadesse, M. G., Szapary, P. O., Witztum, J. L., FitzGerald, G. A., & Rader, D. J. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.01.026 · Cited by 124 · see citing works
Self-citationDjamali, A., Sadowski, E. A., Muehrer, R. J., Reese, S. R., Smavatkul, C., Vidyasagar, A., Fain, S. B., Lipscomb, R. C., Hullett, D. H., Samaniego-Picota, M., et al. (2006) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00222.2006 · Cited by 124 · see citing works
Mervaala, E. M. A., Cheng, Z. J., Tikkanen, I. T., Lapatto, R., Nurminen, K., Vapaatalo, H., Müller, D. N., Fiebeler, A., Ganten, U., Ganten, D., et al. (2001) · Hypertension · doi:10.1161/01.hyp.37.2.414 · Cited by 122 · see citing works
Jurt, U., Gori, T., Ravandi, A., Babaei, S., Zeman, P. R., & Parker, J. D. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01414-0 · Cited by 121 · see citing works
Platelets and diabetes mellitus
Santilli, F., Simeone, P., Liani, R., & Davı̀, G. (2015) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2015.05.002 · Cited by 123 · see citing works
Inflammation and thrombosis in diabetes
Hess, K., & Grant, P. J. (2011) · Thrombosis and Haemostasis · doi:10.1160/ths10-11-0739 · Cited by 117 · see citing works
Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury
Redecha, P. B., van Rooijen, N., Torry, D. S., & Girardi, G. (2009) · Blood · doi:10.1182/blood-2008-12-194258 · Cited by 117 · see citing works
Recent advances in the biochemistry and clinical relevance of the isoprostane pathway
Musiek, E. S., Yin, H., Milne, G. L., & Morrow, J. D. (2005) · Lipids · doi:10.1007/s11745-005-1460-7 · Cited by 117 · see citing works
Vassalle, C., Botto, N., Andreassi, M. G., Berti, S. L., & Biagini, A. (2003) · Coronary Artery Disease · doi:10.1097/01.mca.0000063504.13456.c3 · Cited by 117 · see citing works
Devaraj, S., Hirany, S. V., Burk, R. F., & Jialal, I. (2001) · Clinical Chemistry · doi:10.1093/clinchem/47.11.1974 · Cited by 116 · see citing works
Eicosanoids and Their Drugs in Cardiovascular Diseases: Focus on Atherosclerosis and Stroke
Capra, V., Bäck, M., Barbieri, S. S., Camera, M., Tremoli, E., & Rovati, G. E. (2012) · Medicinal Research Reviews · doi:10.1002/med.21251 · Cited by 115 · see citing works
Low density lipoprotein oxidation, antioxidants, and atherosclerosis
Catapano, A. L., Maggi, F. M., & Tragni, E. (2000) · Current Opinion in Cardiology · doi:10.1097/00001573-200009000-00008 · Cited by 113 · see citing works
Iuliano, L., Praticò, D., Greco, C., Mangieri, E., Scibilia, G., FitzGerald, G. A., & Violi, F. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01040-8 · Cited by 112 · see citing works
Self-citationReduction of Isoprostanes and Regression of Advanced Atherosclerosis by Apolipoprotein E
Tangirala, R. K., Praticò, D., FitzGerald, G. A., Chun, S. H., Tsukamoto, K., Maugeais, C., Usher, D. C., Puré, E., & Rader, D. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m003324200 · Cited by 112 · see citing works
Self-citationTakebayashi, K., Matsumoto, S., Aso, Y., & Inukai, T. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1718 · Cited by 110 · see citing works
Abraham, N. G., Rezzani, R., Rodella, L. F., Kruger, A. L., Taller, D., Volti, G. L., Goodman, A. I., & Kappas, A. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01187.2003 · Cited by 109 · see citing works
Patrignani, P., Panara, M. R., Tacconelli, S., Seta, F., Bucciarelli, T., Ciabattoni, G., Alessandrini, P., Mezzetti, A., Santini, G., Sciulli, M. G., et al. (2000) · Circulation · doi:10.1161/01.cir.102.5.539 · Cited by 108 · see citing works
Self-citationF2-isoprostane formation, measurement and interpretation: The role of exercise
Nikolaidis, M. G., Kyparos, A., & Vrabas, I. S. (2010) · Progress in Lipid Research · doi:10.1016/j.plipres.2010.10.002 · Cited by 106 · see citing works
Liang, Y., Wei, P., Duke, R. W., Reaven, P. D., Harman, S. M., Cutler, R. G., & Heward, C. B. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01018-3 · Cited by 105 · see citing works
Montero, A., Munger, K. A., Khan, R. Z., Valdivielso, J. M., Morrow, J. D., Guasch, A., Ziyadeh, F. N., & Badr, K. F. (2000) · Kidney International · doi:10.1111/j.1523-1755.2000.00368.x · Cited by 103 · see citing works
Oxidative stress and diabetes mellitus
Kuyvenhoven, J. P., & Meinders, A. E. (1999) · European Journal of Internal Medicine · doi:10.1016/s0953-6205(99)00009-6 · Cited by 103 · see citing works
Böger, R. H., Bode‐Böger, S. M., Phivthong‐ngam, L., Brandes, R. P., Schwedhelm, E., Mügge, A., Böhme, M., Tsikas, D., & Frölich, J. C. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00145-2 · Cited by 103 · see citing works
- Authors
- Patrono, C., & FitzGerald, G. A.
- Affiliations
- University of Pennsylvania (US)
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 1997-11
- Volume
- 17
- Issue
- 11
- Pages
- 2309-2315
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2087724955
- Cited by
- 453
- References
- 61
- Citations by year
- 2026: 1 · 2025: 3 · 2023: 4 · 2022: 5 · 2021: 2 · 2020: 4 · 2019: 6 · 2018: 3 · 2017: 6 · 2016: 9 · 2015: 11 · 2014: 8 · 2013: 10 · 2012: 15
- FWCI
- 20.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Arteriosclerosis Thrombosis and Vascular Biology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Bayer
- Wellcome Trust
- European Commission
- National Institutes of Health
- National Heart, Lung, and Blood Institute (P50HL054500, 1P50HL54500)
- National Center for Research Resources (MO1-RR-00040, M01RR000040)
- Topics
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Eicosanoids and Hypertension Pharmacology
- Health Sciences › Medicine › Pharmacology › Inflammatory mediators and NSAID effects
- Keywords
- isoprostanes, lipid peroxidation, oxidative stress, arachidonic acid metabolism, atherothrombosis, urinary biomarkers, cardiovascular risk factors, smoking, diabetes mellitus, hypercholesterolemia, ischemia-reperfusion injury, lipid peroxidation inhibitors, dose-finding
- MeSH terms
- Antioxidants, Arteriosclerosis, Cardiovascular Diseases, Diabetes Mellitus, Free Radicals, Humans, Hyperlipidemias, Immunoassay, Indicator Dilution Techniques, Gas Chromatography-Mass Spectrometry, Platelet Aggregation, Prostaglandins F, Risk Factors, Thrombosis, Vasoconstrictor Agents, Lipid Peroxidation, Dinoprost, Biomarkers, Oxidative Stress, F2-Isoprostanes
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