A Switchable Biocompatible Polymer Surface with Self‐Sterilizing and Nonfouling Capabilities

A Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein

Ostuni, E., Chapman, R. G., Holmlin, R. E., Takayama, S., & Whitesides, G. M. (2001) · Langmuir · doi:10.1021/la010384m · Cited by 1,799

Designing surfaces that kill bacteria on contact

Tiller, J. C., Liao, C.-J., Lewis, K., & Klibanov, A. M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111143098 · Cited by 1,196

Zwitterionic Polymers Exhibiting High Resistance to Nonspecific Protein Adsorption from Human Serum and Plasma

Ladd, J. J., Zhang, Z., Chen, S., Hower, J. C., & Jiang, S. (2008) · Biomacromolecules · doi:10.1021/bm701301s · Cited by 821

Inhibition of bacterial adhesion and biofilm formation on zwitterionic surfaces

Cheng, G., Zhang, Z., Chen, S., Bryers, J. D., & Jiang, S. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.05.041 · Cited by 740

Self-Assembled Monolayers That Resist the Adsorption of Proteins and the Adhesion of Bacterial and Mammalian Cells

Ostuni, E., Chapman, R., Liang, M. N., Meluleni, G. J., Pier, G. B., Ingber, D. E., & Whitesides, G. M. (2001) · Langmuir · doi:10.1021/la010552a · Cited by 563

Surface Grafted Sulfobetaine Polymers via Atom Transfer Radical Polymerization as Superlow Fouling Coatings

Zhang, Z., Chen, S., Chang, Y., & Jiang, S. (2006) · The Journal of Physical Chemistry B · doi:10.1021/jp057266i · Cited by 546

Permanent, nonleaching antibacterial surfaces: 1. Synthesis by atom transfer radical polymerization

Lee, S. B., Koepsel, R. R., Morley, S. W., Matyjaszewski, K., Sun, Y., & Russell, A. J. (2004) · Biomacromolecules · doi:10.1021/bm034352k · Cited by 545

In vitro and in vivo antimicrobial activity of covalently coupled quaternary ammonium silane coatings on silicone rubber

Gottenbos, B., van der Mei, H. C., Klatter, F. A., Nieuwenhuis, P., & Busscher, H. J. (2002) · Biomaterials · doi:10.1016/s0142-9612(01)00263-0 · Cited by 505

Phosphorylcholine-based polymers and their use in the prevention of biofouling

Lewis, A. L. (2000) · Colloids and Surfaces B Biointerfaces · doi:10.1016/s0927-7765(99)00152-6 · Cited by 500

Surface-Responsive Materials

Russell, T. P. (2002) · Science · doi:10.1126/science.1075997 · Cited by 496

Novel antifouling polysulfone matrix membrane modified with zwitterionic polymer

Wu, C., Zheng, J., & Hu, J. (2021) · Journal of Saudi Chemical Society · doi:10.1016/j.jscs.2021.101281 · Cited by 7

Poly(oxanorbornene)‐Based Polyzwitterions with Systematically Increasing Hydrophobicity: Synthesis, Physical Characterization, and Biological Properties

Paschke, S., Marx, F., Bleicher, V., Eickenscheidt, A., & Lienkamp, K. (2022) · Macromolecular Chemistry and Physics · doi:10.1002/macp.202200334 · Cited by 7

Research Progress in Preparation and Biomedical Application of Functional Medical Polyurethane Elastomers※

Zhang, Z., Liu, L., Xu, D., Zhang, R., Shi, H., Luan, S., & Yin, J. (2022) · 化学学报 · doi:10.6023/a21120593 · Cited by 7

Drug Delivery and Bone Infection

Vallet‐Regí, M., Colilla, M., & Izquierdo‐Barba, I. (2018) · The Enzymes · doi:10.1016/bs.enz.2018.08.001 · Cited by 7

Bifunctional Bioactive Polymer Surfaces with Micrometer and Submicrometer-sized Structure: The Effects of Structure Spacing and Elastic Modulus on Bioactivity

Elsayed, S. M., Widyaya, V. T., Shafi, Y., Eickenscheidt, A., & Lienkamp, K. (2019) · Molecules · doi:10.3390/molecules24183371 · Cited by 8

Temporary In Situ Hydrogel Dressings for Colon Polypectomies

Cook, K., Naguib, N., Price, C. E., Katharios-Lanwermeyer, S., Kirsch, J. R., Cortes, K., Hohl, K., O’Toole, G. A., & Grinstaff, M. W. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00549 · Cited by 6

Nanomaterial-based smart coatings for antibacterial, antifungal, and antiviral activities

Rani, D., Singh, R., Kush, P., & Kumar, P. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91762-9.00008-3 · Cited by 6

Environmentally responsive polyelectrolytes and zwitterionic polymers

Bernards, M. T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-85709-713-2.00002-x · Cited by 6

Anti-adhesive and Antibacterial Polymer Brushes

Neoh, K. G., Shi, Z., & Kang, E. T. (2012) · Springer eBooks · doi:10.1007/978-1-4614-1031-7_16 · Cited by 6

Bottlebrush Polymer-Functionalized Graphene Oxide-Based Multifunctional Poly(vinyl alcohol) Nanocomposite Films with Exceptional Performance

Deng, T., Xu, B., Zhang, L., & Li, C. (2022) · Macromolecules · doi:10.1021/acs.macromol.2c01201 · Cited by 6

Antimicrobial and Anti‐Inflammatory Intelligent Surfaces

Griesser, H. J., Hall, H., Jenkins, A. T. A., Griesser, S. S., & Vasilev, K. A. (2012) · Wiley eBooks · doi:10.1002/9781118181249.ch6 · Cited by 6

Modulation of Peptoid Nanostructure for Antibiofilm Hydrogel Interfaces

Yun, J. W., Park, I.-S., Yoon, H. G., Woo, J., Kim, D.-Y., Yang, W., Choi, J., Min, D., Lee, J.-H., Seo, J., et al. (2026) · Nano Letters · doi:10.1021/acs.nanolett.5c05266 · Cited by 5

Hydration and ion interactions of zwitterionic homopolymers with varying carbon spacer lengths

Christiansen, D. E., Cheng, G., & Mehraeen, S. (2022) · Process Safety and Environmental Protection · doi:10.1016/j.cherd.2022.07.032 · Cited by 5

Smart Copolymer Surface Derived from Geminized Cationic Amphiphilic Polymers for Reversibly Switchable Bactericidal and Self-Cleaning Abilities

Chen, T., Situ, C., Huang, H., Liang, K., Zhao, L., Wang, Z., Zhao, J., Li, Y., Duan, C., & Sun, H. (2023) · Langmuir · doi:10.1021/acs.langmuir.3c01005 · Cited by 5

Antimicrobial Polymers and Surfaces – Natural Mimics or Surpassing Nature?

Krumm, C., & Tiller, J. C. (2016) · Royal Society of Chemistry eBooks · doi:10.1039/9781782626664-00490 · Cited by 5

Preparation of a Novel Type of Zwitterionic Polymer and the Antifouling PDMS Coating

Ma, X., Fu, X., & Sun, J. (2022) · Biomimetics · doi:10.3390/biomimetics7020050 · Cited by 5

A spiropyran-decorated nanocoating for dynamically regulating bacteria/cell adhesion and detachment

Li, J., Ma, Z., Li, A., Huang, S., Zhang, Y., Xue, Y., Song, X., Zhang, Y., Hong, S., Wang, M., et al. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb01719b · Cited by 5

Novel Antibacterial Coatings for Biofouling and Biocorrosion Inhibition

Pehkonen, S. O., & Yuan, S. (2018) · Interface science and technology · doi:10.1016/b978-0-12-813584-6.00008-9 · Cited by 6

Sterically Demanding Flexible Phosphoric Acids for Constructing Efficient and Multi‐Purpose Asymmetric Organocatalysts

Scharinger, F., Pálvölgyi, Á. M., Weisz, M., Weil, M., Stanetty, C., Schnürch, M., & Bica, K. (2022) · Angewandte Chemie · doi:10.1002/ange.202202189 · Cited by 5

Silver Containing Biomaterials

Poulter, N., Vasilev, K. A., Griesser, S. S., & Griesser, H. J. (2012) · Springer eBooks · doi:10.1007/978-1-4614-1031-7_14 · Cited by 5

Antimicrobial/Antifouling Surfaces Obtained by Surface Modification

Rodríguez‐Hernández, J. (2016) · Springer eBooks · doi:10.1007/978-3-319-47961-3_5 · Cited by 6

Reversibly Charge-Switching Polyzwitterionic/Polycationic Coatings for Biomedical Applications: Optimizing the Molecular Structure for Improved Stability

Schneider, S. H. E., Lehnert, K., Thome, M. A., Kraegeloh, A., & Lienkamp, K. (2025) · Langmuir · doi:10.1021/acs.langmuir.4c04358 · Cited by 4

Co-assembly of zwitterionic and cationic polymers for antibacterial and antithrombotic surfaces via weak electrostatic interactions

Wang, J., Liu, J., Wei, Y., Wang, T., Hu, Y., Xiong, Y., Luo, R., Zhang, F., & Wang, Y. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124114 · Cited by 4

Manufacture of Chemically Modified Antibacterial Surfaces

Pingle, H., Wang, P., McArthur, S. L., & Kingshott, P. (2015) · Springer eBooks · doi:10.1007/978-3-319-18594-1_5 · Cited by 4

A self-cleaning surface based on UV-activatable, AgCl micropumps for bacterial killing and removal

Liu, P., Quan, K., Liu, M., Wang, H., van der Mei, H. C., Busscher, H. J., & Zhang, Z. (2022) · Chemical Communications · doi:10.1039/d2cc01343f · Cited by 4

Preparation of antimicrobial polycarboxybetaine‐based hydrogels for studies of drug loading and release

Xu, S., Zeng, R., Cheng, J., Cai, Z., Wen, X., & Pi, P. (2013) · Journal of Applied Polymer Science · doi:10.1002/app.39839 · Cited by 4

Advancements in Antimicrobial Biomaterials: New Avenues to Ameliorate Wound Infections and Implant-associated Infections

Mukherjee, S., Patra, D., Maity, S., & Haldar, J. (2024) · Current Indian Science · doi:10.2174/012210299x314905241203104146 · Cited by 3

Biofilm formation, problems and diseases: Methods for film eradication, a nanostructured material-based approach

Mohanty, S., & Paul, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822956-9.00005-2 · Cited by 3

Surface Modifiers for Reducing Bacterial Contamination in Medicine and Food Industry

Cherednichenko, Y. V., Ishmukhametov, I., & Fakhrullina, G. (2025) · Colloid Journal · doi:10.1134/s1061933x24601082 · Cited by 3

Synthesis of N-(2 amino benzothiazole) methacylamide monomer and its copolymers for antimicrobial coating application by RAFT polymerization

Lokhande, G. P., Chambhare, S. U., & Jagtap, R. N. (2016) · International Journal of Polymeric Materials · doi:10.1080/00914037.2015.1129951 · Cited by 3

Synthesis and Antibacterial Performance of Functional Organic–Inorganic Silica Nanocomposites Based on Novel Zwitterionic Polymer

Sun, Y., Chen, C.-L., Xu, H., Xu, G., Zhao, L. X., & Lang, M. (2017) · Journal of Inorganic and Organometallic Polymers and Materials · doi:10.1007/s10904-017-0589-6 · Cited by 3

A Multiple-Stimuli-Responsive Amphiphilic Copolymer for Antifouling and Antibacterial Functionality via a “Resistance–Kill–Release” Mechanism

Liao, X., Niu, K., Liu, F., & Zhang, Y. (2022) · Molecules · doi:10.3390/molecules27165059 · Cited by 3

Synthesis and properties of the antibacterial hydrogels with enhanced mechanical strengths

Liu, Q., Wen, X., Xu, S., Pi, P., Cheng, J., & Zeng, R. (2015) · Colloid & Polymer Science · doi:10.1007/s00396-015-3548-1 · Cited by 3

Special Issue: Advances in Engineered Nanostructured Antibacterial Surfaces and Coatings

Balaure, P. C. (2022) · Coatings · doi:10.3390/coatings12081041 · Cited by 3

Cytotoxic Effects and Biocompatibility of Antimicrobial Materials

Bazaka, O., & Bazaka, K. (2015) · Springer eBooks · doi:10.1007/978-3-319-18594-1_7 · Cited by 3

Zwitterionic molecule layer for inhibiting microbial corrosion of copper alloy

Xu, F., Qiu, Z., Qiu, R., Yang, J., & Lin, C. (2018) · Anti-Corrosion Methods and Materials · doi:10.1108/acmm-12-2016-1744 · Cited by 3

Construction strategies and the development trend of antibacterial surfaces

Wu, H., Liu, W., Liu, C., & Ai, C. (2022) · Biointerphases · doi:10.1116/6.0002147 · Cited by 3

Tissue‐Implant Antimicrobial Interfaces

Marsich, E., Travan, A., Donati, I., Turco, G., Bellomo, F., & Paoletti, S. (2011) · Wiley eBooks · doi:10.1002/9781118150887.ch15 · Cited by 3

Antimicrobial Coatings and Other Surface Modifications for Infection Prevention

Mittelman, M. W., Mittelman, M. W., & Mukherjee, N. (2016) · doi:10.1002/9781119308713.ch2 · Cited by 3

Examination of functional zwitterionic polymer hydrogels based on polypyridinium salt by a convenient cross-linker

Sun, Y., Chen, C.-L., Xu, H., Lei, K., Zhao, L. X., & Lang, M. (2019) · Journal of Macromolecular Science Part A · doi:10.1080/10601325.2019.1568195 · Cited by 2

Physiological pH Responsive Integrated Antifouling and Antimicrobial Interface with Long-Term Activity via Amino-Carboxylate Coordination Chemistry

Liu, J., Lin, X., Ma, J., Wang, L., Tang, Y. D., Ma, N., Zhao, Y., & Zhang, W. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c01011 · Cited by 2

Biofilm formation, problems, and diseases: Methods for film eradication, a nanostructured material based approach

Mohanty, S., & Paul, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822503-5.00015-1 · Cited by 2

Conceptual Analysis of Microbial Processes and Drug Delivery System by the Active Ingredients of Nigella sativa

(2022) · Biointerface Research in Applied Chemistry · doi:10.33263/briac131.009 · Cited by 2

Self‐Assembly Anchored Cationic Copolymer Interfaces for Applying the Control of Counterion‐Induced Bacteria Killing/Release Procedure

Chiu, C., Lin, H., Yen, T., & Chang, Y. (2022) · Macromolecular Bioscience · doi:10.1002/mabi.202200207 · Cited by 2

Nanoteknoloji Temelli Antimikrobiyal Yüzey Kaplama Teknolojileri ve Potansiyel Uygulama Alanları

Gökmen, G. G., & Kışla, D. (2022) · Turkish Journal of Agriculture - Food Science and Technology · doi:10.24925/turjaf.v10i5.821-837.4735 · Cited by 1

Polymeric brushes for enhanced biological applications: advancements in sustainable approach

Prakash, A., Sridhar, S. B., Wali, A. F., Talath, S., Shareef, J., Malviya, R., & Warsi, M. H. (2025) · International Journal of Polymeric Materials · doi:10.1080/00914037.2025.2469167 · Cited by 1

Carboxybetaine-Based Zwitterionic Polyurethanes with Ultralow Fouling Properties

Wang, H., Song, H., & Cheng, G. (2026) · Langmuir · doi:10.1021/acs.langmuir.5c06550 · Cited by 1

Preparation of Antimicrobial PHEMA-g-PCBMAE Hydrogels with Improved Mechanical Properties

Zeng, R., Cheng, J., Xu, S. P., Liu, Q., Wen, X., & Pi, P. H. (2014) · Applied Mechanics and Materials · doi:10.4028/www.scientific.net/amm.576.49 · Cited by 1

Nanofillers in the Antibacterial and Antifungal Coating Material

Sen, N. (2024) · Springer eBooks · doi:10.1007/978-981-99-3516-1_106-1 · Cited by 1

Strategies for Improvement of Hemocompatibility

Yu, L., Wang, Y., Kulka, M. W., Wei, Q., & Haag, R. (2025) · Royal Society of Chemistry eBooks · doi:10.1039/9781839165412-00046 · Cited by 1

Biological Consequences of the Blood–Surface Interaction

(2016) · Royal Society of Chemistry eBooks · doi:10.1039/9781782622048-00136 · Cited by 1

Antimicrobial coatings for soft materials

Kulaga, E. (2014) · theses.fr (ABES) · doi:10.70675/74a3f43dz3f16z491dz8214z3f0c1a89554e · Cited by 1

Improving Biocompatibility of Implantable Bioelectronics using Zwitterionic Cysteine

Lin, P. H. (2017) · UWSpace (University of Waterloo) · Cited by 1

Medical Devices and Preparative Medicine: Polymer Drug Application

Aguilar, M. R., García‐Fernández, L., López-Donaire, M. L., Parra, F., Rojo, L., Rodríguez, G., Fernández‐Gutiérrez, M., & Román, J. S. (2017) · CRC Press eBooks · doi:10.1081/e-ebppc-120052267 · Cited by 1

Zwitterionic Polymeric Materials

Damodaran, V. B., Leszczak, V., Reynolds, M. M., & Popat, K. C. (2017) · CRC Press eBooks · doi:10.1081/e-ebppc-120050037 · Cited by 1

Molecular Engineering Approaches against Germs, Spores and Biofilm Formation

Mi, L. (2014) · ResearchWorks at the University of Washington (University of Washington)

Developing Antifouling Marine Coatings Using Protein-Resistant Betaine-Based Polymers

Zhang, Z., & Loose, C. R. (2011) · ACS symposium series · doi:10.1021/bk-2011-1086.ch007

Understanding Properties of Zwitterionic Materials from Their Molecular Structures

Shao, Q. (2014) · ResearchWorks at the University of Washington (University of Washington)

STRUCTURE-ACTIVITY RELATIONSHIPS AND SURFACE IMMOBILIZATION OF POLYCATIONIC ANTIMICROBIALS

Widodo, M., & Raharjani, S. A. R. (2020) · Arena Tekstil · doi:10.31266/at.v35i1.5722

Zwitterionic Polymeric Materials

Damodaran, V. B., Leszczak, V., Reynolds, M. M., & Popat, K. C. (2016) · Taylor & Francis eBooks · doi:10.1081/e-ebpp-120050037

Medical Devices and Preparative Medicine: Polymer Drug Application

Aguilar, M. R., García‐Fernández, L., López-Donaire, M. L., Parra, F., Rojo, L., Rodríguez, G., Fernández‐Gutiérrez, M., & Román, J. S. (2015) · Taylor & Francis eBooks · doi:10.1081/e-ebpp-120052267

Polymer Brushes with Chemical Responses

Chu, E., & Sidorenko, A. (2022) · Royal Society of Chemistry eBooks · doi:10.1039/9781839166136-00413

Pioneers in Applied and Fundamental Interfacial Chemistry: Shaoyi Jiang

Chen, Z., Zheng, J., & Walker, G. C. (2025) · Langmuir · doi:10.1021/acs.langmuir.5c03492

Nanofillers in the Antibacterial and Antifungal Coating Material

Sen, N. (2025) · Springer eBooks · doi:10.1007/978-981-96-2407-2_106

Bifunctional and Smart Antibacterial Surfaces

Yu, Q. (2025) · doi:10.1002/9783527846979.ch04

Programmable hydrogel dressing for enhanced wound healing: Fuel-driven switchable antibacterial and antifouling properties

Zhou, W., Jiang, X., Dong, W., Xu, X., Zhao, P., Zhao, Y., Fan, X., Cao, M., Li, B., Lü, Y., et al. (2025) · Cell Biomaterials · doi:10.1016/j.celbio.2025.100300

Antibacterial cellulose composite films via in-situ transesterification of sunflower oil

Villani, S., Narayanan, A., Friuli, M., Padmanabhan, S. K., Mergola, L., Lazzoi, M. R., Sole, R. D., Vincenti, L., Rinaldi, R., Calcagnile, M., et al. (2026) · Cellulose · doi:10.1007/s10570-025-06929-6

Regenerable Biocidal Surfaces Enabled by Self-Assembled Block Copolymer Polyelectrolytes

Manouras, T., Vagias, A., Koufakis, E., Anastasiadis, S. H., Müller‐Buschbaum, P., & Vamvakaki, M. (2026) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6c10442

Antimicrobial zwitterionic hydrogel coatings for kidney disease-associated catheters: current challenges and advances

Ma, Y., Wang, W., Deng, N., Sun, J., Lu, W., Zhao, W., & Zhao, C. (2026) · Biomaterials Science · doi:10.1039/d6bm00542j

Non-migratory nano-enabled antimicrobial interfaces for chilled meat preservation: Interfacial mechanisms, migration safety, and food validation

Feng, Y., Liu, K., Tang, Y., Liu, X., Mu, W., Song, Y., Duan, Y., & Liu, G. (2026) · Food Research International · doi:10.1016/j.foodres.2026.120691

Artificial intelligence and machine learning for sustainable polymeric marine antifouling coatings: current evidence, challenges, and future perspectives

Elsawy, M. M. (2026) · Journal of Materials Science Polymers · doi:10.1007/s44493-026-00028-z

A smart antibacterial surface with switchable bacteria-antifouling and killing capabilities

Pang, Q., Xiang, J., Xin, J., & Ma, L. (2022) · Materials Letters · doi:10.1016/j.matlet.2022.132476 · Cited by 7

Polymer‐Based Surfaces Designed to Reduce Biofilm Formation: From Antimicrobial Polymers to Strategies for Long‐Term Applications

Riga, E. K., Vöhringer, M., Widyaya, V. T., & Lienkamp, K. (2017) · Macromolecular Rapid Communications · doi:10.1002/marc.201700216 · Cited by 112

Hierarchical Polymer Brushes with Dominant Antibacterial Mechanisms Switching from Bactericidal to Bacteria Repellent

Yan, S., Luan, S., Shi, H., Xu, X., Zhang, J., Yuan, S., Yang, Y., & Yin, J. (2016) · Biomacromolecules · doi:10.1021/acs.biomac.6b00115 · Cited by 145

Antibacterial surfaces based on poly(cationic liquid) brushes: switchability between killing and releasing via anion counterion switching

Dong, Y., Xiong, X., Lu, X., Wu, Z., & Chen, H. (2016) · Journal of Materials Chemistry B · doi:10.1039/c6tb01464j · Cited by 34

pH responsive zwitterionic-to-cationic transition for safe self-defensive antibacterial application

Zhang, J., Liu, L., Wang, L., Zhu, W., & Wang, H. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01717e · Cited by 17