Cited by 371Polymer Surface Interaction StudiesAntimicrobial agents and applicationsMarine Biology and Environmental Chemistry

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A Switchable Biocompatible Polymer Surface with Self‐Sterilizing and Nonfouling Capabilities

Cheng, Gang, Xue, Hong, Zhang, Zheng, Chen, Shengfu, Jiang, Shaoyi·2008·Angewandte Chemie International Edition

DOI 10.1002/anie.200803570

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Abstract

Trap, kill, and release: An antimicrobial cationic surface can effectively kill bacterial cells and switch to a nonfouling zwitterionic surface which releases dead microorganisms upon hydrolysis (see picture). This biocompatible nonfouling surface can prevent further attachment of proteins and microorganisms and the formation of a biofilm on the surface.

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Self-citation
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Authors: Cheng, G., Xue, H., Zhang, Z., Chen, S., & Jiang, S.
Affiliations: University of Washington (US)
ORCID: Cheng, Gang
Zhang, Zheng
Chen, Shengfu
Jiang, Shaoyi
Venue: Angewandte Chemie International Edition
Publisher: Wiley
Published: 2008-10-28
Volume: 47
Issue: 46
Pages: 8831-8834
ISSN: 1433-7851 (ISSN-L)
1521-3773
DOI: 10.1002/anie.200803570
OpenAlex: W2043772624
Cited by: 371
References: 28
Citations by year: 2026: 8 · 2025: 16 · 2024: 11 · 2023: 15 · 2022: 31 · 2021: 24 · 2020: 24 · 2019: 27 · 2018: 26 · 2017: 30 · 2016: 35 · 2015: 31 · 2014: 27 · 2013: 21 · 2012: 11
FWCI: 5.79
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Angewandte Chemie International Edition (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
Physical Sciences › Engineering › Ocean Engineering › Marine Biology and Environmental Chemistry
Keywords: cationic surfaces, zwitterionic surfaces, self-sterilization, non-fouling surfaces, biofilm inhibition, protein adsorption, hydrolysis, biomaterials
MeSH terms: Anti-Bacterial Agents, Biocompatible Materials, Escherichia coli, Fibrinogen, Polymers, Surface Properties, Surface Plasmon Resonance, Microbial Viability

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A Switchable Biocompatible Polymer Surface with Self‐Sterilizing and Nonfouling Capabilities

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