The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Au@Pt Nanoparticle Encapsulated Target‐Responsive Hydrogel with Volumetric Bar‐Chart Chip Readout for Quantitative Point‐of‐Care Testing
Abstract
Point‐of‐care testing (POCT) with the advantages of speed, simplicity, portability, and low cost is critical for the measurement of analytes in a variety of environments where access to laboratory infrastructure is lacking. While qualitative POCTs are widely available, quantitative POCTs present significant challenges. Here we describe a novel method that integrates an Au core/Pt shell nanoparticle (Au@PtNP) encapsulated target‐responsive hydrogel with a volumetric bar‐chart chip (V‐Chip) for quantitative POCT. Upon target introduction, the hydrogel immediately dissolves and releases Au@PtNPs, which can efficiently catalyze the decomposition of H 2 O 2 to generate a large volume of O 2 to move of an ink bar in the V‐Chip. The concentration of the target introduced can be visually quantified by reading the traveling distance of the ink bar. This method has the potential to be used for portable and quantitative detection of a wide range of targets without any external instrument.
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Du, W., Li, L., Nichols, K. P., & Ismagilov, R. F. (2009) · Lab on a Chip · doi:10.1039/b908978k · Cited by 351
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Yu, Z., Tang, Y., Cai, G., Ren, R., & Tang, D. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.8b04635 · Cited by 341
Song, P., Ye, D., Zuo, X., Li, J., Wang, J., Liu, H., Hwang, M. T., Chao, J., Su, S., Wang, L., et al. (2017) · Nano Letters · doi:10.1021/acs.nanolett.7b01006 · Cited by 258
Metadata
- Authors
- Zhu, Z., Guan, Z., Jia, S., Lei, Z., Lin, S., Zhang, H., Ma, Y., Tian, Z., & Yang, C. J.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2014-08-11
- Volume
- 53
- Issue
- 46
- Pages
- 12503-12507
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2142036107
- Cited by
- 303
- References
- 1
- FWCI
- 11.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Zhu, Z., Guan, Z., Jia, S., Lei, Z., Lin, S., Zhang, H., Ma, Y., Tian, Z., & Yang, C. J. (2014). Au@Pt Nanoparticle Encapsulated Target‐Responsive Hydrogel with Volumetric Bar‐Chart Chip Readout for Quantitative Point‐of‐Care Testing. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201405995
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