The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Phthalocyanine‐Assembled Nanodots as Photosensitizers for Highly Efficient Type I Photoreactions in Photodynamic Therapy
Abstract
Owing to their unique, nanoscale related optical properties, nanostructures assembled from molecular photosensitizers (PSs) have interesting applications in phototheranostics. However, most nanostructured PS assemblies are super‐quenched, thus, preventing their use in photodynamic therapy (PDT). Although some of these materials undergo stimuli‐responsive disassembly, which leads to partial recovery of PDT activity, their therapeutic potentials are unsatisfactory owing to a limited ability to promote generation reactive oxygen species (ROS), especially via type I photoreactions (i.e., not by 1 O 2 generation). Herein we demonstrate that a new, nanostructured phthalocyanine assembly, NanoPcA, has the ability to promote highly efficient ROS generation via the type I mechanism. The results of antibacterial studies demonstrate that NanoPcA has potential PDT applications.
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Cites
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Nanoparticles in Photodynamic Therapy
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Photodynamic therapy and anti-tumour immunity
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Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
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Antibacterial drug discovery in the resistance era
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Clinical development and potential of photothermal and photodynamic therapies for cancer
Li, X., Lovell, J. F., Yoon, J., & Chen, X. (2020) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-0410-2 · Cited by 3,456
Self-citationRecent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813
Self-citationConquering the Hypoxia Limitation for Photodynamic Therapy
Wan, Y., Fu, L., Li, C., Lin, J., & Huang, P. (2021) · Advanced Materials · doi:10.1002/adma.202103978 · Cited by 705
Nguyen, V.-N., Qi, S., Kim, S., Kwon, N., Kim, G., Yim, Y., Park, S., & Yoon, J. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b09220 · Cited by 457
Self-citationPhototherapy in cancer treatment: strategies and challenges
Cai, Y., Chai, T., Nguyen, W., Liu, J., Xiao, E., Ran, X., Ran, Y., Du, D., Chen, W., & Chen, X. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02140-y · Cited by 453
Metadata
- Authors
- Li, X., Lee, D., Huang, J., & Yoon, J.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2018-07-04
- Volume
- 57
- Issue
- 31
- Pages
- 9885-9890
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2808855660
- Cited by
- 426
- References
- 37
- FWCI
- 32.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, X., Lee, D., Huang, J., & Yoon, J. (2018). Phthalocyanine‐Assembled Nanodots as Photosensitizers for Highly Efficient Type I Photoreactions in Photodynamic Therapy. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201806551
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