The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Optical Multiplexed Bioassays for Improved Biomedical Diagnostics
Abstract
Conventional analytical methods based on the detection of a single disease marker may not be sufficiently accurate because the progression of disease generally involves multiple chemicals and biomolecules. The drive for simultaneous analysis of multiple targets, which plays a key role in both basic biomedical research and clinical applications, demands the development of multiplexed bioassays with high‐throughput. In this minireview, we summarize the recent progress in optical multiplexed analytical techniques for improving biomedical diagnostics, in which fluorescence and surface enhanced Raman scattering (SERS) with distinctive optical features are chosen as the main readout signals. Focusing on multiplexed strategies in the biomedical field, a selection of recent contributions from biosensing of multiple analytes and multicolor cellular tracking to in vivo multiplexed bioimaging are highlighted. Finally, we frame the future challenges and opportunities for multiplexed bioanalysis.
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Cites
Spatially resolved, highly multiplexed RNA profiling in single cells
Chen, K. H., Boettiger, A. N., Moffitt, J. R., Wang, S., & Zhuang, X. (2015) · Science · doi:10.1126/science.aaa6090 · Cited by 2,969
Self-citationSecond window for in vivo imaging
Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848
Next-generation in vivo optical imaging with short-wave infrared quantum dots
Bruns, O. T., Bischof, T. S., Harris, D. K., Franke, D., Shi, Y., Riedemann, L., Bartelt, A., Jaworski, F. B., Carr, J. A., Rowlands, C. J., et al. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-017-0056 · Cited by 686
A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues
Wan, H., Yue, J., Zhu, S., Uno, T., Zhang, X., Yang, Q., Yu, K., Hong, G., Wang, J., Li, L., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03505-4 · Cited by 450
Noonan, J., Asiala, S. M., Grassia, G., MacRitchie, N., Gracie, K., Carson, J., Moores, M., Girolami, M., Bradshaw, A. C., Guzik, T. J., et al. (2018) · Theranostics · doi:10.7150/thno.28665 · Cited by 69
Cited by
NIR-II bioimaging of small organic molecule
Su, Y., Yu, B., Wang, S., Cong, H., & Shen, Y. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120717 · Cited by 251
Self-citationHighly Stable and Bright NIR-II AIE Dots for Intraoperative Identification of Ureter
Du, J., Liu, S., Zhang, P., Liu, H., Li, Y., He, W., Li, C., Chau, J. H. C., Kwok, R. T. K., Lam, J. W. Y., et al. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b22957 · Cited by 70
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Metadata
- Authors
- Fan, Y., Wang, S., & Zhang, F.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2019-07
- Volume
- 58
- Issue
- 38
- Pages
- 13208-13219
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2939959898
- Cited by
- 170
- References
- 5
- FWCI
- 7.38
- Type
- journal article
- Language
- en
- Open access
- closed
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