The DOI matches its Crossref record; 79 of the 79 references it cites were found in a registry or an index.
BODIPY‐Based Photodynamic Agents for Exclusively Generating Superoxide Radical over Singlet Oxygen
Abstract
Developing Type‐I photosensitizers is considered as an efficient approach to overcome the deficiency of traditional photodynamic therapy (PDT) for hypoxic tumors. However, it remains a challenge to design photosensitizers for generating reactive oxygen species by the Type‐I process. Herein, we report a series of α,β‐linked BODIPY dimers and a trimer that exclusively generate superoxide radical (O 2−.) by the Type‐I process upon light irradiation. The triplet formation originates from an effective excited‐state relaxation from the initially populated singlet (S 1) to triplet (T 1) states via an intermediate triplet (T 2) state. The low reduction potential and ultralong lifetime of the T 1 state facilitate the efficient generation of O 2−. by inter‐molecular charge transfer to molecular oxygen. The energy gap of T 1‐S 0 is smaller than that between 3 O 2 and 1 O 2 thereby precluding the generation of singlet oxygen by the Type‐II process. The trimer exhibits superior PDT performance under the hypoxic environment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Lee, C., Yang, W., & Parr, R. G. (1988) · Physical Review B · doi:10.1103/physrevb.37.785 · Cited by 100,874
Density-functional exchange-energy approximation with correct asymptotic behavior
Becke, A. D. (1988) · Physical Review A · doi:10.1103/physreva.38.3098 · Cited by 53,711
A new mixing of Hartree–Fock and local density-functional theories
Becke, A. D. (1993) · The Journal of Chemical Physics · doi:10.1063/1.464304 · Cited by 16,515
Barone, V., & Cossi, M. (1998) · The Journal of Physical Chemistry A · doi:10.1021/jp9716997 · Cited by 10,121
Photodynamic therapy for cancer
Dolmans, D. E. J. G. J., Fukumura, D., & Jain, R. K. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1071 · Cited by 6,758
Photodynamic therapy of cancer: An update
Agostinis, P., Berg, K., Cengel, K. A., Foster, T. H., Girotti, A. W., Gollnick, S. O., Hahn, S. M., Hamblin, M. R., Juzeniene, A., Kessel, D., et al. (2011) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20114 · Cited by 5,145
Dougherty, T. J., Gomer, C. J., Henderson, B. W., Jori, G., Kessel, D., Korbelik, M., Moan, J., & Peng, Q. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.12.889 · Cited by 4,716
Andersson, K., Malmqvist, P.-Å., & Roos, B. O. (1992) · The Journal of Chemical Physics · doi:10.1063/1.462209 · Cited by 3,877
Second-order perturbation theory with a CASSCF reference function
Andersson, K., Malmqvist, P. A., Roos, B. O., Sadlej, A. J., & Wolinski, K. (1990) · The Journal of Physical Chemistry · doi:10.1021/j100377a012 · Cited by 3,331
The Chemistry of Fluorescent Bodipy Dyes: Versatility Unsurpassed
Ulrich, G., Ziessel, R., & Harriman, A. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200702070 · Cited by 3,161
Cited by
Tongue cancer tailored photosensitizers for NIR-II fluorescence imaging guided precise treatment
Yin, B., Qin, Q., Li, Z., Wang, Y., Liu, X., Liu, Y., Huan, S., Zhang, X., & Song, G. (2022) · Nano Today · doi:10.1016/j.nantod.2022.101550 · Cited by 65
Huang, X., Zhang, W., Peng, Y., Gao, L., Wang, F., Wang, L., & Wei, X. (2022) · ACS Nano · doi:10.1021/acsnano.1c08580 · Cited by 46
Wang, Q., Liu, J., Yang, L., Tao, Z., Feng, J., Li, S., Wang, X., Gao, L., Tang, W., & Fan, Q. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202423165 · Cited by 15
Metadata
- Authors
- Teng, K., Chen, W., Niu, L., Fang, W., Cui, G., & Yang, Q.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2021-08-03
- Volume
- 60
- Issue
- 36
- Pages
- 19912-19920
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W3177653351
- Cited by
- 445
- References
- 79
- FWCI
- 40.71
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: BODIPY‐Based Photodynamic Agents for Exclusively Generating Superoxide Radical over Singlet Oxygen. https://app.cochat.ai/papers/10.1002/anie.202106748
- The paper
- Teng, K., Chen, W., Niu, L., Fang, W., Cui, G., & Yang, Q. (2021). BODIPY‐Based Photodynamic Agents for Exclusively Generating Superoxide Radical over Singlet Oxygen. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.202106748
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
