Tongue cancer tailored photosensitizers for NIR-II fluorescence imaging guided precise treatment

Cancer statistics, 2020

Siegel, R. L., Miller, K. D., & Jemal, A. (2020) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21590 · Cited by 20,444 · see citing works

The role of porphyrin chemistry in tumor imaging and photodynamic therapy

Ethirajan, M., Chen, Y., Joshi, P., & Pandey, R. K. (2010) · Chemical Society Reviews · doi:10.1039/b915149b · Cited by 2,038 · see citing works

Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy

Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813 · see citing works

Overcoming the Achilles' heel of photodynamic therapy

Fan, W., Huang, P., & Chen, X. S. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00616g · Cited by 1,686 · see citing works

Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application

Zhao, X., Liu, J., Fan, J., Chao, H., & Peng, X. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00173b · Cited by 1,278 · see citing works

Near‐Infrared‐II Molecular Dyes for Cancer Imaging and Surgery

Zhu, S., Tian, R., Antaris, A. L., Chen, X. S., & Dai, H. (2019) · Advanced Materials · doi:10.1002/adma.201900321 · Cited by 968 · see citing works

Intelligent MnO2 Nanosheets Anchored with Upconversion Nanoprobes for Concurrent pH‐/H2O2‐Responsive UCL Imaging and Oxygen‐Elevated Synergetic Therapy

Fan, W., Bu, W., Shen, B., He, Q., Cui, Z., Liu, Y., Zheng, X., Zhao, K., & Shi, J. (2015) · Advanced Materials · doi:10.1002/adma.201405141 · Cited by 668 · see citing works

Heavy-Atom-Free Photosensitizers: From Molecular Design to Applications in the Photodynamic Therapy of Cancer

Nguyen, V.-N., Yan, Y., Zhao, J., & Yoon, J. (2021) · Accounts of Chemical Research · doi:10.1021/acs.accounts.0c00606 · Cited by 650 · see citing works

Perfluorocarbon‐Loaded Hollow Bi2Se3 Nanoparticles for Timely Supply of Oxygen under Near‐Infrared Light to Enhance the Radiotherapy of Cancer

Song, G., Liang, C., Yi, X., Zhao, Q., Cheng, L., Yang, K., & Liu, Z. (2016) · Advanced Materials · doi:10.1002/adma.201504617 · Cited by 587 · see citing works

Two-photon excitation nanoparticles for photodynamic therapy

Shen, Y., Shuhendler, A. J., Ye, D., Xu, J., & Chen, H. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00442c · Cited by 569 · see citing works

Glycosylated Porphyrins, Phthalocyanines, and Other Porphyrinoids for Diagnostics and Therapeutics

Singh, S., Aggarwal, A., Bhupathiraju, N. V. S. D. K., Arianna, G., Tiwari, K., & Drain, C. M. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00244 · Cited by 568 · see citing works

Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

Xie, J., Wang, Y., Choi, W., Jangili, P., Ge, Y., Xu, Y., Kang, J., Liu, L., Zhang, B., Xie, Z., et al. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01370f · Cited by 526 · see citing works

BODIPY‐Based Photodynamic Agents for Exclusively Generating Superoxide Radical over Singlet Oxygen

Teng, K., Chen, W., Niu, L., Fang, W., Cui, G., & Yang, Q. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202106748 · Cited by 447 · see citing works

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer

Jiang, Y., Huang, J., Xu, C., & Pu, K. (2021) · Nature Communications · doi:10.1038/s41467-021-21047-0 · Cited by 443 · see citing works

Rational Design of Conjugated Small Molecules for Superior Photothermal Theranostics in the NIR‐II Biowindow

Li, S., Deng, Q., Zhang, Y., Li, X., Wen, G., Cui, X., Wan, Y., Huang, Y., Chen, J., Liu, Z., et al. (2020) · Advanced Materials · doi:10.1002/adma.202001146 · Cited by 370 · see citing works

Oral cancer: Current role of radiotherapy and chemotherapy

Huang, S. H., & O'Sullivan, B. P. (2013) · Medicina oral, patología oral y cirugía bucal · doi:10.4317/medoral.18772 · Cited by 349 · see citing works

Type I photodynamic therapy by organic–inorganic hybrid materials: From strategies to applications

Wang, Y., Liu, Y., Sun, H., & Guo, D. (2019) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2019.05.016 · Cited by 344 · see citing works

Rose-bengal-conjugated gold nanorods for in vivo photodynamic and photothermal oral cancer therapies

Wang, B., Wang, J., Liu, Q., Huang, H., Chen, M., Li, K., Li, C., Yu, X., & Chu, P. K.-H. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.11.066 · Cited by 311 · see citing works

Modulating Hypoxia via Nanomaterials Chemistry for Efficient Treatment of Solid Tumors

Liu, Y., Jiang, Y., Zhang, M., Tang, Z., He, M., & Bu, W. (2018) · Accounts of Chemical Research · doi:10.1021/acs.accounts.8b00214 · Cited by 308 · see citing works

Conjugated‐Polyelectrolyte‐Based Polyprodrug: Targeted and Image‐Guided Photodynamic and Chemotherapy with On‐Demand Drug Release upon Irradiation with a Single Light Source

Yuan, Y., Liu, J., & Liu, B. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201402189 · Cited by 303 · see citing works

Type I photosensitizers based on phosphindole oxide for photodynamic therapy: apoptosis and autophagy induced by endoplasmic reticulum stress

Zhuang, Z., Dai, J., Yu, M., Li, J., Shen, P., Hu, R., Lou, X., Zhao, Z., & Tang, B. Z. (2020) · Chemical Science · doi:10.1039/d0sc00785d · Cited by 291 · see citing works

Global incidence of oral and oropharynx cancer in patients younger than 45 years versus older patients: A systematic review

Hussein, A. A., Helder, M. N., de Visscher, J. G. A. M., Leemans, C. R., Braakhuis, B. J. M., de Vet, H. C. W., & Forouzanfar, T. (2017) · European Journal of Cancer · doi:10.1016/j.ejca.2017.05.026 · Cited by 273 · see citing works

An NIR‐II‐Emissive Photosensitizer for Hypoxia‐Tolerant Photodynamic Theranostics

Li, L., Shao, C., Liu, T., Chao, Z., Chen, H., Xiao, F., He, H., Wei, Z., Zhu, Y., Wang, H., et al. (2020) · Advanced Materials · doi:10.1002/adma.202003471 · Cited by 254 · see citing works

Time‐Dependent Photodynamic Therapy for Multiple Targets: A Highly Efficient AIE‐Active Photosensitizer for Selective Bacterial Elimination and Cancer Cell Ablation

Li, Q., Li, Y., Min, T., Gong, J., Du, L., Phillips, D. L., Liu, J., Lam, J. W. Y., Sung, H. H. Y., Williams, I. D., et al. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201909706 · Cited by 211 · see citing works

A New Single 808 nm NIR Light‐Induced Imaging‐Guided Multifunctional Cancer Therapy Platform

He, F., Yang, G., Yang, P., Yu, Y., Lv, R., Li, C., Dai, Y., Gai, S., & Lin, J. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201500464 · Cited by 199 · see citing works

Activatable fluorescence sensors for in vivo bio-detection in the second near-infrared window

Zhao, M., Li, B., Zhang, H., & Zhang, F. (2020) · Chemical Science · doi:10.1039/d0sc04789a · Cited by 169 · see citing works

A Feasible Strategy of Fabricating Type I Photosensitizer for Photodynamic Therapy in Cancer Cells and Pathogens

Chen, K., He, P., Wang, Z., & Tang, B. Z. (2021) · ACS Nano · doi:10.1021/acsnano.1c01577 · Cited by 167 · see citing works

Fine-tuning the electronic structure of heavy-atom-free BODIPY photosensitizers for fluorescence imaging and mitochondria-targeted photodynamic therapy

Qi, S., Kwon, N., Yim, Y., Nghĩa, N. V., & Yoon, J. (2020) · Chemical Science · doi:10.1039/d0sc01171a · Cited by 163 · see citing works

Oral Cancer: A Historical Review

Inchingolo, F., Santacroce, L., Ballini, A., Topi, S., Dipalma, G., Haxhirexha, K., Bottalico, L., & Charitos, I. A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17093168 · Cited by 156 · see citing works

An Acceptor–Donor–Acceptor Structured Small Molecule for Effective NIR Triggered Dual Phototherapy of Cancer

He, Z., Zhao, L., Zhang, Q., Chang, M., Li, C., Zhang, H., Lu, Y., & Chen, Y. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201910301 · Cited by 140 · see citing works

Mitochondria‐Targeted Polydopamine Nanocomposite with AIE Photosensitizer for Image‐Guided Photodynamic and Photothermal Tumor Ablation

Chen, Y., Ai, W., Guo, X., Li, Y., Ma, Y., Chen, L., Zhang, H., Wang, T. C., Zhang, X., & Wang, Z. (2019) · Small · doi:10.1002/smll.201902352 · Cited by 137 · see citing works

Engineered Protein Photo‐Thermal Hydrogels for Outstanding In Situ Tongue Cancer Therapy

Su, J., Lü, S., Jiang, S., Li, B., Liu, B., Sun, Q., Li, J., Wang, F., & Wei, Y. Q. (2021) · Advanced Materials · doi:10.1002/adma.202100619 · Cited by 131 · see citing works

Mesenchymal Stem Cells Functionalized Sonodynamic Treatment for Improving Therapeutic Efficacy and Compliance of Orthotopic Oral Cancer

Sun, L., Xu, Y., Zhang, X., Gao, Y., Chen, J., Zhou, A., Lu, Q., Wang, Z., Shao, K., Wu, H., et al. (2020) · Advanced Materials · doi:10.1002/adma.202005295 · Cited by 107 · see citing works

Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer

Liu, J., Chen, C., Wei, T., Gayet, O., Loncle, C., Borge, L., Dusetti, N., Ma, X., Marson, D., Laurini, E., et al. (2021) · Exploration · doi:10.1002/exp.20210003 · Cited by 104 · see citing works

Metal-Free Nanoassemblies of Water-Soluble Photosensitizer and Adenosine Triphosphate for Efficient and Precise Photodynamic Cancer Therapy

Li, Z., Li, S., Guo, Y., Yuan, C., Yan, X., & Schanze, K. S. (2021) · ACS Nano · doi:10.1021/acsnano.0c09913 · Cited by 96 · see citing works

Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy

Jin, G., Feng, G., Qin, W., Tang, B. Z., Liu, B., & Li, K. (2016) · Chemical Communications · doi:10.1039/c5cc07818k · Cited by 95 · see citing works

Classification of tongue cancer resection and treatment algorithm

Mannelli, G., Arcuri, F., Agostini, T., Innocenti, M., Raffaini, M., & Spinelli, G. (2018) · Journal of Surgical Oncology · doi:10.1002/jso.24991 · Cited by 89 · see citing works

Achieving High‐Performance Photothermal and Photodynamic Effects upon Combining D–A Structure and Nonplanar Conformation

Chen, J., Wen, K., Chen, H., Jiang, S., Wu, X., Lv, L., Peng, A., Zhang, S., & Huang, H. (2020) · Small · doi:10.1002/smll.202000909 · Cited by 86 · see citing works

Reactive Oxygen Species-Responsive Nanoparticles Based on PEGlated Prodrug for Targeted Treatment of Oral Tongue Squamous Cell Carcinoma by Combining Photodynamic Therapy and Chemotherapy

Shi, S., Zhang, L., Zhu, M., Wan, G., Li, C., Zhang, J., Wang, Y., & Wang, Y. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b08269 · Cited by 85 · see citing works

Electron-acceptor density adjustments for preparation conjugated polymers with NIR-II absorption and brighter NIR-II fluorescence and 1064 nm active photothermal/gas therapy

Sun, P., Jiang, X., Sun, B., Wang, H., Li, J., Fan, Q., & Huang, W. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121319 · Cited by 82 · see citing works

Nanoparticle delivery of Wnt-1 siRNA enhances photodynamic therapy by inhibiting epithelial–mesenchymal transition for oral cancer

Ma, C., Shi, L., Huang, Y., Shen, L., Peng, H. F., Zhu, X., & Zhou, G. (2017) · Biomaterials Science · doi:10.1039/c6bm00833j · Cited by 67 · see citing works

Nanobody modified high-performance AIE photosensitizer nanoparticles for precise photodynamic oral cancer therapy of patient-derived tumor xenograft

Wu, W., Shi, L., Duan, Y., Xu, S., Shen, L., Zhu, T., Hou, L., Meng, X., & Liu, B. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120870 · Cited by 60 · see citing works

Prostate PDT dosimetry

Zhu, T. C., & Finlay, J. C. (2006) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2006.08.002 · Cited by 55 · see citing works

Molybdenum Diphosphide Nanorods with Laser‐Potentiated Peroxidase Catalytic/Mild‐Photothermal Therapy of Oral Cancer

Qian, M., Cheng, Z., Luo, G., Galluzzi, M., Shen, Y., Li, Z., Yang, H., & Yu, X. (2021) · Advanced Science · doi:10.1002/advs.202101527 · Cited by 46 · see citing works

Treatment improvement and better patient care: which is the most important one in oral cavity cancer?

Felice, F. D., Musio, D., Terenzi, V., Valentini, V., Cassoni, A., Tombolini, M., VINCENTIIS, M. D., & Tombolini, V. (2014) · Radiation Oncology · doi:10.1186/s13014-014-0263-x · Cited by 43 · see citing works

Oxygen-Embedded Quinoidal Acene Based Semiconducting Chromophore Nanoprobe for Amplified Photoacoustic Imaging and Photothermal Therapy

Yin, B., Wang, Y., Zhang, C., Zhao, Y., Wang, Y., Teng, L., Yang, Y., Zeng, Z., Huan, S., Song, G., et al. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b04429 · Cited by 34 · see citing works

A thermally activated delayed fluorescence photosensitizer for photodynamic therapy of oral squamous cell carcinoma under low laser intensity

Hu, S., Huang, B., Pu, Y., Xia, C., Zhang, Q. Y., Guo, S., Wang, Y., & Huang, X. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb00719j · Cited by 31 · see citing works

Utilization of Nonradiative Excited-State Dissipation for Promoted Phototheranostics Based on an AIE-Active Type I ROS Generator

Wang, Y., Sun, Y., Ran, J., Yang, H., Xiao, S., Yang, J., Yang, C., Wang, H., & Liu, Y. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c19008 · Cited by 30 · see citing works

MG53 Inhibits the Progression of Tongue Cancer Cells through Regulating PI3K‐AKT Signaling Pathway: Evidence from 3D Cell Culture and Animal Model

Yin, W., Liu, Y., & Bian, Z. (2019) · Small · doi:10.1002/smll.201805492 · Cited by 26 · see citing works

World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders

Robledo‐Sierra, J., Amy, D. P. B., Varoni, E. M., Bavarian, R., Simonsen, J. L., Paster, B. J., Wade, W. G., Kerr, A. R., Peterson, D. E., & Lau, E. F. (2019) · Oral Diseases · doi:10.1111/odi.13107 · Cited by 26 · see citing works

Cervical lymph node metastasis from early-stage squamous cell carcinoma of the oral tongue

Yuasa‐Nakagawa, K., Shibuya, H., Yoshimura, R., Miura, M., Watanabe, H., Kishimoto, S., & Omura, K. (2013) · Acta Oto-Laryngologica · doi:10.3109/00016489.2012.748988 · Cited by 21 · see citing works

Risk factors for osteonecrosis of the jaw in oral cancer patients after surgery and eventual adjuvant treatment: The potential role of chemotherapy

Lai, T., Wang, T., Liu, C., Chao, T., Chen, T., & Hu, Y. (2017) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2017.05.001 · Cited by 19 · see citing works

Near-infrared-II light excitation thermosensitive liposomes for photoacoustic imaging-guided enhanced photothermal-chemo synergistic tumor therapy

Dai, Y., Du, W., Gao, D., Zhu, H., Zhang, F., Chen, K., Ni, H., Li, M., Fan, Q., & Shen, Q. (2021) · Biomaterials Science · doi:10.1039/d1bm01669e · Cited by 19 · see citing works

Photodynamic therapy combined with immunotherapy for an advanced esophageal cancer with an obstruction post metal stent implantation: A case report and Literature Review.

Wang, X., Maswikiti, E. P., Zhu, J., Ma, Y.-L., Zheng, P., Yu, Y., Wang, B.-F., Gao, L., & Chen, H. (2021) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2021.102671 · Cited by 19 · see citing works

Lowering photosensitizer doses and increasing fluences induce apoptosis in tumor bearing mice

Haedicke, K., Gräfe, S., Teichgraeber, U. K., & Hilger, I. (2016) · Biomedical Optics Express · doi:10.1364/boe.7.002641 · Cited by 7 · see citing works

Fluorination Enhances NIR‐II Emission and Photothermal Conversion Efficiency of Phototheranostic Agents for Imaging‐Guided Cancer Therapy

Li, C., Jiang, G., Yu, J., Ji, W., Liu, L., Zhang, P., Du, J., Zhan, C., Wang, J., & Tang, B. Z. (2022) · Advanced Materials · doi:10.1002/adma.202208229 · Cited by 167 · see citing works

Chemical Design of Magnetic Nanomaterials for Imaging and Ferroptosis-Based Cancer Therapy

Xu, W., Guan, G., Yue, R., Dong, Z., Lei, L., Kang, H., & Song, G. (2025) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00546 · Cited by 98 · see citing works

Recent Advances in Strategies to Enhance Photodynamic and Photothermal Therapy Performance of Single‐Component Organic Phototherapeutic Agents

Fang, L., Chen, Z., Dai, J., Pan, Y., Tu, Y., Meng, Q., Diao, Y., Yang, S., Guo, W., Li, L., et al. (2025) · Advanced Science · doi:10.1002/advs.202409157 · Cited by 88 · see citing works

Deciphering Oxygen‐Independent Augmented Photodynamic Oncotherapy by Facilitating the Separation of Electron‐Hole Pairs

Hu, X., Fang, Z.-T., Sun, F., Zhu, C., Jia, M., Miao, X., Huang, L., Hu, W., Fan, Q., Yáng, Z., et al. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202401036 · Cited by 84 · see citing works

Advances in organic nano-architectures based on NIR-II small-molecule fluorophores for biomedical imaging and therapy

Bian, H., Ma, D., Nan, Y., Kim, M. H., Kim, S. H., Chen, X., Peng, X., & Yoon, J. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216551 · Cited by 82 · see citing works

Small-molecule fluorescent probes for detecting hydrogen peroxide in biological systems

Zhou, Y., Yang, X., Lee, H., Yan, M., & Yoon, J. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216785 · Cited by 77 · see citing works

Photodynamic therapy with NIR-II probes: review on state-of-the-art tools and strategies

Yang, Y., Jiang, S., Stanciu, S. G., Peng, H., Wu, A., & Yang, F. (2024) · Materials Horizons · doi:10.1039/d4mh00819g · Cited by 74 · see citing works

Remote Control of Energy Transformation‐Based Cancer Imaging and Therapy

Xu, H., Kim, D., Zhao, Y., Kim, C., Song, G., Hu, Q., Kang, H., & Yoon, J. (2024) · Advanced Materials · doi:10.1002/adma.202402806 · Cited by 73 · see citing works

Dual‐Pronged Attack: pH‐Driven Membrane‐Anchored NIR Dual‐Type Nano‐Photosensitizer Excites Immunogenic Pyroptosis and Sequester Immune Checkpoint for Enhanced Prostate Cancer Photo‐Immunotherapy

Wang, H., He, Z., Gao, Y., Feng, D., Wei, X., Huang, Y., Hou, J., Li, S., & Zhang, W. (2023) · Advanced Science · doi:10.1002/advs.202302422 · Cited by 68 · see citing works

π Bridge Engineering-Boosted Dual Enhancement of Type-I Photodynamic and Photothermal Performance for Mitochondria-Targeting Multimodal Phototheranostics of Tumor

Fang, L., Meng, Q., Zhang, Y., Su, R. J., Xing, F., Yang, H., Hou, Y., Ma, P., Huang, K., & Feng, S. (2023) · ACS Nano · doi:10.1021/acsnano.3c06542 · Cited by 61 · see citing works

An Activatable Phototheranostic Nanoplatform for Tumor Specific NIR‐II Fluorescence Imaging and Synergistic NIR‐II Photothermal‐Chemodynamic Therapy

Dai, Y., Zhang, F., Chen, K., Sun, Z., Wang, Z., Xue, Y., Li, M., Fan, Q., Shen, Q., & Zhao, Q. (2023) · Small · doi:10.1002/smll.202206053 · Cited by 60 · see citing works

Antimicrobial Photodynamic Therapy for the Remote Eradication of Bacteria

Yan, E., Kwek, G., Qing, N. S., Lingesh, S., & Xing, B. (2023) · ChemPlusChem · doi:10.1002/cplu.202300009 · Cited by 55 · see citing works

A lipid droplet-targeted multifunctional AIE-active fluorescent probe for hydrogen peroxide detection and imaging-guided photodynamic therapy

Li, X., Xu, W., Yang, Z., Li, S., Gu, X., Yuan, T., Li, C., Wang, Y., & Hua, J. (2022) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2022.132892 · Cited by 51 · see citing works

A novel afterglow nanoreporter for monitoring cancer therapy

Liao, S., Wang, Y., Li, Z., Zhang, Y., Yin, X., Huan, S., Zhang, X., Liu, S., & Song, G. (2022) · Theranostics · doi:10.7150/thno.77457 · Cited by 48 · see citing works

Biomarker-activatable photosensitizers with aggregation-induced emission characteristics for photodynamic therapy

Yu, Q., Li, J., Yu, Y., Yan, M., Xu, D., & Yin, S. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216056 · Cited by 41 · see citing works

pH-Responsive NIR-II phototheranostic agents for in situ tumor vascular monitoring and combined anti-vascular/photothermal therapy

Bian, S., Zheng, X., Liu, W., Gao, Z., Wan, Y., Li, J., Ren, H., Zhang, W., Lee, C., & Wang, P. (2023) · Biomaterials · doi:10.1016/j.biomaterials.2023.122380 · Cited by 39 · see citing works

Ultrasound activated probe for disease imaging and therapy In-Vivo

Liu, X., Wang, J., Wu, Y., Wu, M. C., & Song, J. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115158 · Cited by 37 · see citing works

Photonic control of image-guided ferroptosis cancer nanomedicine

Ko, M. J., Yoo, W., Min, S., Zhang, Y. S., Joo, J., Kang, H., & Kim, D. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215532 · Cited by 36 · see citing works

Emerging biomedical imaging-based companion diagnostics for precision medicine

Liao, S., Zhou, M., Wang, Y., Lu, C., Yin, B., Zhang, Y., Liu, H., Yin, X., & Song, G. (2023) · iScience · doi:10.1016/j.isci.2023.107277 · Cited by 29 · see citing works

Nanogenosensors based on aptamers and peptides for bioelectrochemical cancer detection: an overview of recent advances in emerging materials and technologies

Kangarshahi, B. M., & Naghib, S. M. (2024) · Discover Applied Sciences · doi:10.1007/s42452-024-05681-z · Cited by 29 · see citing works

Organic Afterglow Nanoparticles in Bioapplications

Shen, H., Liao, S., Li, Z., Wang, Y., Huan, S., Zhang, X., & Song, G. (2023) · Chemistry - A European Journal · doi:10.1002/chem.202301209 · Cited by 28 · see citing works

Donor-Engineered Covalent Organic Framework Nanophotocatalysts Enabling an Oxygen-Independent Radical Storm for Hypoxic Cancer Phototherapy

Zhou, Q., Li, C., Huang, G., Zhao, M., Yang, T., Ji, Y., Wu, Y., Chen, H., & Ge, Z. (2025) · ACS Nano · doi:10.1021/acsnano.5c11020 · Cited by 24 · see citing works

Renal clearable magnetic nanoparticles for magnetic resonance imaging and guided therapy

Zhang, Q., Yin, R., Guan, G., Liu, H., & Song, G. (2023) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1929 · Cited by 24 · see citing works

Insights into the organic semiconducting photosensitizers for hypoxia-tolerant type I photodynamic therapy

Hu, X., Zhu, C., Sun, F., Yang, J. S., Chen, Z., Ao, H., Cui, C., Yáng, Z., & Huang, W. (2022) · Nano TransMed · doi:10.26599/ntm.2022.9130010 · Cited by 23 · see citing works

NIR-II fluorescence lymphatic imaging and intraoperative navigation based on the “isolated cage” monodisperse strategy

Qi, S., Wang, Y., Zhu, Y., Zhang, X., Wang, X., Yu, X., Yang, K., Bai, B., Feng, Y., Lei, J., et al. (2023) · Nano Today · doi:10.1016/j.nantod.2023.101795 · Cited by 23 · see citing works

Advances in NIR-Responsive Natural Macromolecular Hydrogel Assembly Drugs for Cancer Treatment

Zhao, C., Pan, B., Wang, T., Yang, H., Vance, D., Li, X., Zhao, H., Hu, X., Yang, T., Chen, Z., et al. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15122729 · Cited by 22 · see citing works

Polymer mediated light responsive therapeutics delivery system to treat cancer

Kapoor, D. U., Maheshwari, N., Bag, A., Sharma, D. M. C., Prajapati, B. G., & Maheshwari, R. (2024) · European Polymer Journal · doi:10.1016/j.eurpolymj.2024.112923 · Cited by 23 · see citing works

A pH-Responsive Drug Delivery System Based on Conjugated Polymer for Effective Synergistic Chemo-/Photodynamic Therapy

Zhang, C., Yuan, Q., Zhang, Z., & Tang, Y. (2023) · Molecules · doi:10.3390/molecules28010399 · Cited by 22 · see citing works

Suppressing Non‐Radiative Decay via Cyanation: A Promising Design Strategy for Bright Organic NIR‐II Fluorophores

Wang, W., Shao, J., Xie, D., Wang, L., Xu, K., Mei, A., Ma, H., Han, W., Chen, P., & Dong, X. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202522260 · Cited by 19 · see citing works

Aggregation-induced Emission Probe for Fluorescence/Photoacoustic Dual-modality Imaging and Photodynamic/Photothermal Treatment

Chen, P., Zhang, G., Li, J., Ma, L., Zhou, J., Zhu, M., Li, S., & Wang, Z. (2024) · Chemical Research in Chinese Universities · doi:10.1007/s40242-024-3256-9 · Cited by 19 · see citing works

High‐Performance NIR‐II Fluorescent Type I/II Photosensitizer Enabling Augmented Mild Photothermal Therapy of Tumors by Disrupting Heat Shock Proteins

Jiang, Q., Li, J., Du, Z., Li, M., Chen, L., Zhang, X., Tang, X., Shen, Y., Ma, D., Wen, L., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400962 · Cited by 19 · see citing works

NIR-triggered photodynamic therapy of traumatic heterotopic ossification with a type II collagen-targeted photosensitizer

Wang, Z., Sun, C., Yu, Y., Zhang, D., Qi, B., Li, Z., Yi, X., & Yu, A. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100822 · Cited by 18 · see citing works

Enhanced Near-Infrared-Excitable Organic Afterglow Nanoparticles for Deep-Tissue Multimodal Imaging via Singlet Oxygen-Mediated Energy Transfer

Yu, Y., Li, Z., Liao, S., Yin, B., Zhang, Q., Fu, J., Zhang, C., Zhou, Y., & Song, G. (2025) · Research · doi:10.34133/research.0834 · Cited by 17 · see citing works

Bromine Substitution Improves the Photothermal Performance of π‐Conjugated Phototheranostic Molecules

Wan, F., Wang, H., Gu, Y., Fan, G., Hou, S., Yu, J., Wang, M., He, F., & Tian, L. (2023) · Chemistry - A European Journal · doi:10.1002/chem.202303502 · Cited by 17 · see citing works

Organic small-molecule NIR-II fluorophores for tumor phototheranostics

Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science & Applications · doi:10.1038/s41377-026-02212-w · Cited by 22 · see citing works

Repurposing organic semiconducting nanomaterials to accelerate clinical translation of NIR-II fluorescence imaging

Hu, X., Sun, F., Zhu, C., Yáng, Z., & Huang, W. (2022) · Nano Research · doi:10.1007/s12274-022-5145-1 · Cited by 17 · see citing works

NIR-II photothermal therapy mediated by polymer-based nanoparticles to enhance checkpoint inhibitor immunotherapy for inhibiting lymph node metastasis in oral squamous cell carcinoma

Zhu, W., Guo, Y. J., Huang, J., Zhang, Y., Ni, Z., Wei, M., 刘来奎, Li, Y., Zhang, M., & Tang, B. Z. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102351 · Cited by 15 · see citing works

Deciphering Oxygen‐Independent Augmented Photodynamic Oncotherapy by Facilitating the Separation of Electron‐Hole Pairs

Hu, X., Fang, Z.-T., Sun, F., Zhu, C., Jia, M., Miao, X., Huang, L., Hu, W., Fan, Q., Yáng, Z., et al. (2024) · Angewandte Chemie · doi:10.1002/ange.202401036 · Cited by 14 · see citing works

Advanced second near-infrared fluorophores for bioapplications

Bai, Q., Yang, Q., Liu, Y., Li, A., Yin, X.-B., & Wu, S. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217146 · Cited by 14 · see citing works

有机近红外二区荧光探针研究进展

Jiahui, 刘. L., Yanqing, 杨. Y., Rui, 马. M., & Kebin, 施. S. (2023) · Chinese Journal of Lasers · doi:10.3788/cjl230819 · Cited by 12 · see citing works

Porphyrin-Based Organic Nanoparticles with NIR-IIa Fluorescence for Orthotopic Glioblastoma Theranostics

Yang, M., Chen, D., Zhang, L., Ye, M., Song, Y., Xu, J., Cao, Y., & Liu, Z. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c03012 · Cited by 11 · see citing works

Effective design of organic luminogens for near-infrared-II fluorescence imaging and photo-mediated therapy

Kamya, E., Lu, Z., Cao, Y., & Pei, R. (2022) · Journal of Materials Chemistry B · doi:10.1039/d2tb01903e · Cited by 10 · see citing works

Multifunctional Nanoplatform for NIR-II Imaging-Guided Synergistic Oncotherapy

Wang, Q., Xia, G., Li, J., Yuan, L., Yu, S., Li, D., Yang, N., Fan, Z., & Li, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242316949 · Cited by 10 · see citing works

Alleviating hypoxia by integrating MnO 2 with metal–organic frameworks coated upconversion nanocomposites for enhanced photodynamic therapy in vitro

Zhou, J., Jiang, M., Zhang, Q., Jiang, Y., Wang, H., & Sun, L. (2024) · Dalton Transactions · doi:10.1039/d4dt02605e · Cited by 10 · see citing works

Recent advances in phototherapeutic nanosystems for oral cancer

Pan, Q., Tang, H., Li, X., Huang, Z., Wu, D., Liu, R., He, B., & Pu, Y. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb01919a · Cited by 9 · see citing works

A unique fluorescence metal-organic framework for ultrasensitive fluorescent and colorimetric bimodal detection of phosphate

Yang, C., Tian, S., Zhao, Y., Yang, L., Mo, L., & Lin, W. (2024) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2024.125571 · Cited by 9 · see citing works

Near‐Infrared‐II Nanomaterials for Activatable Photodiagnosis and Phototherapy

Jiang, W., Lin, L., Wu, P., Lin, H., & Sui, J. H. (2024) · Chemistry - A European Journal · doi:10.1002/chem.202400816 · Cited by 9 · see citing works

Revisiting molecularly conformation-planarized organic dyes for NIR-II fluorescence imaging

An, L., Zheng, L., Zhao, Z., Qu, X., Chen, L., Ou, C., Mou, X., Dong, X., & Cai, Y. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb01334k · Cited by 9 · see citing works

A lipid droplet-targeted Pt( ii ) complex enables photoinduced ferroptosis and apoptosis against cisplatin-resistant cells

Hui, P., Xu, F., Zheng, H., Yao, S., Chen, Y., Gu, X., & Guo, Z. (2026) · Chemical Communications · doi:10.1039/d5cc07220d · Cited by 7 · see citing works

An NIR-II-emitting type-I photosensitizer for efficient hypoxic tumor phototheranostics

Wang, Q., Wang, R., Wang, X., Fu, M., Gao, Y., Feng, J., Geng, R., Yuan, Z., Fan, Q., & Lu, F. (2024) · Chemical Communications · doi:10.1039/d4cc00431k · Cited by 7 · see citing works

A DNA-MOF hybrid nanosystem for prediction of photodynamic therapy efficacy via amplified imaging of apoptotic mRNA

Li, C., Yi, D., Li, M., & Li, Z. (2025) · Nano Today · doi:10.1016/j.nantod.2025.102837 · Cited by 7 · see citing works

Artificial intelligence driven digital whole slide image for intelligent recognition of different development stages of tongue tumor via a new deep learning framework

Xu, X., Peng, X., Hou, C., Chen, Y., Ren, X., Li, Z., Li, G., Cao, L., & Li, Z. (2023) · Engineering Reports · doi:10.1002/eng2.12706 · Cited by 6 · see citing works

FRET-based two-photon benzo[a] phenothiazinium photosensitizer for fluorescence imaging-guided photodynamic therapy

Li, Y., Gao, Z., Yue, X., Lan, M., Zheng, X., Wang, B., Zhao, S., & Song, X. (2023) · Chinese Chemical Letters · doi:10.1016/j.cclet.2023.109133 · Cited by 6 · see citing works

Advances in upconversion nanomaterials for tumor phototherapy

Bian, S., Lu, W., Zhou, L., & Jin, T. (2024) · Materials Today Communications · doi:10.1016/j.mtcomm.2024.110301 · Cited by 4 · see citing works

Revolutionizing cancer therapies with organic photovoltaic non-fullerene acceptors: A deep dive into molecular engineering for advanced phototheranostics

Li, Y., Li, Y., Liao, S., Li, Y., & Yin, S. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.110832 · Cited by 4 · see citing works

Tumor Microenvironment-Modulated Self-illuminating Photodynamic Therapy: A Promising Tool for Deep-Seated and Metastatic Cancer

Attar, G. S., Bhalla, V., & Kumar, M. (2025) · ACS Applied Bio Materials · doi:10.1021/acsabm.5c01699 · Cited by 3 · see citing works

Suppressing Non‐Radiative Decay via Cyanation: A Promising Design Strategy for Bright Organic NIR‐II Fluorophores

Wang, W., Shao, J., Xie, D., Wang, L., Xu, K., Mei, A., Ma, H., Han, W., Chen, P., & Dong, X. (2025) · Angewandte Chemie · doi:10.1002/ange.202522260 · Cited by 3 · see citing works

Tuning Photophysical Conflict Into Synergy: Stereoelectronic Planarity Disruption Unlocks Concurrent Aggregation‐Enhanced ROS and NIR‐II Fluorescence

Liu, J., Ma, D., Li, W., Zhang, X., Cui, J., Zhang, M., Wang, L., Qin, Y., & Chen, H. (2026) · Small · doi:10.1002/smll.202514912 · Cited by 3 · see citing works

Low‐Power NIR‐II Excitable Organic Phototheranostic Agents With NIR‐IIb Emission for Precise Cancer Theranostics

Chen, X., Wu, Y., Hu, Y., Feng, L., Sha, R., Jiang, G., Tang, B. Z., & Wang, J. (2026) · Aggregate · doi:10.1002/agt2.70422 · Cited by 1 · see citing works

Single-component nanoagents with large Stokes shift for high-effect phototheranostics

Zhang, Q., Zhang, X., Fu, M., Xiong, Y., Xiao, T., & Wang, Q. (2023) · Dyes and Pigments · doi:10.1016/j.dyepig.2023.111494 · Cited by 1 · see citing works

Applications of Second Near‐Infrared ( NIR ‐ II ) Theranostic Agents in Dentistry

Liu, Y., Li, Y., & Tian, Y. (2025) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbmb.70004

受体‑给体‑受体型近红外二区荧光光敏剂研究进展（特邀）

Xunwen, 张. Z., Yaowei, 申. S., Wen, 李. L., Dalong, 马. M., Jie, 刘. L., & Wei, 黄. H. (2025) · Chinese Journal of Lasers · doi:10.3788/cjl251135

NIR/Tumor-microenvironment dual-activatable nanorods for concomitant photothermal/photodynamic therapy and hypoxia-amplified chemotherapy

Yu, S., Dai, L., Lv, H., Xue, J., & Chen, J. (2026) · Journal of Porphyrins and Phthalocyanines · doi:10.1142/s1088424626500148

Deciphering endogenous CD8+ T cell interactions using an engineered sortase A system

He, J., Zhang, C., Yu, X., Zhuang, W., Liang, C., Xue, W., Zhang, W., Lei, Y., Nie, W., & Xie, H.-Y. (2026) · Cell Biomaterials · doi:10.1016/j.celbio.2026.100454

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Zhan, L., Chen, Y., Hu, J., Wang, C., Liu, H., Yao, D., & Wang, D. (2026) · Advanced Materials · doi:10.1002/adma.74089

Five-in-One NIR-II phototheranostic nanomedicine for glioblastoma multiforme: Unlocking bio-barriers and photothermal-ferroptotic amplification

Tan, H., Yang, H., Ma, F., Deng, Z., Zhang, R., Dong, R., Jiang, J., Zhu, Y., Xue, S., Wang, S., et al. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124668

NIR‐II‐Excited Type‐I Conjugated Polymer Photosensitizer for Cancer Photodynamic Therapy

Tang, Y., He, C., Chen, C., Zhuang, J., Song, W., Wang, D., Fan, Q., & Liu, B. (2026) · Advanced Materials · doi:10.1002/adma.202520650 · Cited by 23 · see citing works

Recent advances in NIR-II fluorescence imaging-guided type-I photodynamic therapy

Li, H., & Tian, L. (2025) · Chemical Communications · doi:10.1039/d5cc05266a · Cited by 7 · see citing works

Reversible pH-switchable NIR-II nano-photosensitizer for precise imaging and photodynamic therapy of tumors

Chai, Y., Sun, Y., Sheng, Z., Zhu, Y., Du, T., Zhu, B., Yu, H., Dong, B., Liu, Y., & Wang, H.-Y. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.09.001 · Cited by 26 · see citing works

NIR‐II Emissive Superoxide Radical Photogenerator for Photothermal/Photodynamic Therapy against Hypoxic Tumor

Xiao, H., Wang, Y., Chen, J., Xi, S., Duan, Z., Zhan, Q., Tian, Y., Wang, L., Qu, J., & Liu, R. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202303183 · Cited by 20 · see citing works

Molecular Engineering of Near‐Infrared‐II Photosensitizers with Steric‐Hindrance Effect for Image‐Guided Cancer Photodynamic Therapy

Gao, S., Yü, S., Zhang, Y., Wu, A., Zhang, S., Wei, G., Wang, H., Xiao, Z., & Lü, W. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202008356 · Cited by 85 · see citing works