Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

Little, C. B., Barai, A., Burkhardt, D., Smith, S. M., Fosang, A. J., Werb, Z., Shah, M., Thompson, E. W.·2009·Arthritis & Rheumatism

DOI 10.1002/art.25002

Cited by (648)

Items 301–400 of 648

RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes
Benjamin T. McDermott, S. Ellis, George Bou–Gharios, Peter Clegg, Simon R. Tew · 2016 · Osteoarthritis and Cartilage
Estrogen receptor–related receptor α regulation by interleukin‐1β in prostaglandin E2– and cAMP‐dependent pathways in osteoarthritic chondrocytes
Edith Bonnelye, Pascal Reboul, N. Duval, Marco Cardelli, Jane E. Aubin · 2011 · Arthritis & Rheumatism
Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression
Byron Chan, Michael Glogauer, Yongqiang Wang, Jeffrey L. Wrana, Kin Chan, Frank Beier, Supinder Kour Bali, Boris Hinz, Justin Parreno, Sajjad Ashraf et al. · 2023 · Science Advances
Controlling joint instability after anterior cruciate ligament transection inhibits transforming growth factor-beta-mediated osteophyte formation
Kenji Murata, Takanori Kokubun, Katsuya Onitsuka, Yuichiro Oka, Takuma Kano, Yuri Morishita, Kaichi Ozone, N. Kuwabara, J. Nishimoto, Takuya Isho et al. · 2019 · Osteoarthritis and Cartilage
The emerging landscape of nanotheranostic-based diagnosis and therapy for osteoarthritis
Shuyi Xiao, Liang Chen · 2020 · Journal of Controlled Release
Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5
P. Clément-Lacroix, Christopher B. Little, Margaret Mary Smith, Céline Cottereaux, Didier Merciris, Sandrine Meurisse, Patrick Mollat, Robert Touitou, F. Brebion, Romain L. Gosmini et al. · 2021 · Osteoarthritis and Cartilage
Analysis of the Trajectory of Osteoarthritis Development in a Mouse Model by Serial Near‐Infrared Fluorescence Imaging of Matrix Metalloproteinase Activities
Averi A. Leahy, Shadi Abdar Esfahani, Andrea Foote, Carrie K. Hui, Roshni S. Rainbow, Daisy S. Nakamura, Brian Tracey, Umar Mahmood, Li Zeng · 2014 · Arthritis & Rheumatology
RETRACTED: Attenuation of cartilage pathogenesis in post‐traumatic osteoarthritis (PTOA) in mice by blocking the stromal derived factor 1 receptor (CXCR4) with the specific inhibitor, AMD3100
Nathan P. Thomas, Pengcui Li, Braden C. Fleming, Qian Chen, Xiaochun Wei, Pan Xiao‐Hua, Gang Li, Wei Lei · 2015 · Journal of Orthopaedic Research® · Retracted
Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis
Behzâd Javaheri, B. Poulet, Ahmed Aljazzar, Roberto Lopes de Souza, Miriam Piles, Mark Hopkinson, Elaine Shervill, Andrea S. Pollard, Boris Chan, Yu‐Mei Chang et al. · 2017 · Bone
Differentiation of osteophyte types in osteoarthritis – proposal of a histological classification
Susann Junker, Grit Krumbholz, Klaus Frommer, Stefan Rehart, Jürgen Steinmeyer, Markus Rickert, Georg Andreas Schett, Ulf Müller‐Ladner, Elena Neumann · 2015 · Joint Bone Spine
Degradomics defines proteolysis information flow from human knee osteoarthritis cartilage to matched synovial fluid and the contributions of secreted proteases ADAMTS5, MMP13 and CMA1 to articular cartilage breakdown
Sumit Bhutada, Anna Hoyle, Nicolas Santiago Piuzzi, Suneel Apte · 2024 · Osteoarthritis and Cartilage
Identification of Targets of a New Nutritional Mixture for Osteoarthritis Management Composed by Curcuminoids Extract, Hydrolyzed Collagen and Green Tea Extract
Fanny Comblain, Jean‐Emile Dubuc, Cécile Lambert, Christelle Sanchez, Isabelle Lesponne, Samuel Serisier, Yves Edgard Henrotin · 2016 · PLoS ONE
Transcriptional profiling of synovium in a porcine model of early post‐traumatic osteoarthritis
Jakob T. Sieker, Benedikt Lorenz Proffen, Kimberly A. Waller, Kaitlyn E. Chin, Naga Padmini Karamchedu, Matthew R. Akelman, Gabriel S. Perrone, Ata M. Kiapour, Johannes Konrad, Braden C. Fleming et al. · 2018 · Journal of Orthopaedic Research®
Matrix-Bound Growth Factors are Released upon Cartilage Compression by an Aggrecan-Dependent Sodium Flux that is Lost in Osteoarthritis
Stuart J. Keppie, Jessica Mansfield, Xiaodi Tang, Christopher J. Philp, Helen K. Graham, Patrik Önnerfjord, Alanna Wall, Celia McLean, Charles Peter Winlove, Michael J. Sherratt et al. · 2021 · Function
Activities and Molecular Mechanisms of Diterpenes, Diterpenoids, and Their Derivatives in Rheumatoid Arthritis
Muhammad Torequl Islam, Cristina Quispe, Jesús Herrera‐Bravo, Md. Mizanur Rahaman, Rajib Hossain, Chandan Kumar Sarkar, Md Abdur Raihan, Md. Mashrur Chowdhury, Shaikh Jamal Uddin, Jamil A. Shilpi et al. · 2022 · Evidence-based Complementary and Alternative Medicine
Human Umbilical Cord-Derived Mesenchymal Stem Cells Alleviate Psoriasis Through TNF-α/NF-κB/MMP13 Pathway
Xuanyao Ren, Weilong Zhong, Wenting Li, Mindan Tang, Kaoyuan Zhang, Fenli Zhou, Xin Shi, Jun Wu, Bo Yu, Cong Huang et al. · 2023 · Inflammation
Recent Advances in Small Molecule Inhibitors for the Treatment of Osteoarthritis
Jianjing Lin, Shicheng Jia, Weifei Zhang, Mengyuan Nian, Peng Liu, Yang Li, Jianwei Zuo, Wei Li, Hui Zeng, Xintao Zhang · 2023 · Journal of Clinical Medicine
Glycogen Synthase Kinase 3 Inhibition Stimulates Human Cartilage Destruction and Exacerbates Murine Osteoarthritis
Gary J. Litherland, Wang Hui, Martina S. Elias, D. Wilkinson, Sharon Watson, Carmen Huesa, David Alan Young, Andrew D. Rowan · 2014 · Arthritis & Rheumatology
Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytesin vitroand the production of matrix metalloproteinase-3in vivo
Dong-Geun Kang, Hyun Jae Lee, Kun Tae Kim, Sun‐Chul Hwang, Hyun Jae Lee, Jin‐Sung Park · 2017 · Korean Journal of Physiology and Pharmacology
Clinical and omics biomarkers in osteoarthritis diagnosis and treatment
Muhai Deng, Cong Tang, Li Yin, Yunsheng Jiang, Yang Huang, Yong Feng, Cheng Chen · 2025 · Journal of Orthopaedic Translation
Collagen XI mutation lowers susceptibility to load‐induced cartilage damage in mice
Derek T. Holyoak, Miguel Otero, Naa Shidaa Armar, Sophia N. Ziemian, Ariana Otto, Devinne Cullinane, Timothy M. Wright, Steven R. Goldring, Mary B. Goldring, Marjolein C. H. van der Meulen · 2017 · Journal of Orthopaedic Research®
The Effects of Amphiregulin Induced MMP-13 Production in Human Osteoarthritis Synovial Fibroblast
Yi-Te Chen, Chun-Han Hou, S. Hou, Ju-Fang Liu · 2014 · Mediators of Inflammation
Danshen attenuates osteoarthritis-related cartilage degeneration through inhibition of NF-κB signaling pathway in vivo and in vitro
Xilin Xu, Hang Lv, Xiaodong Li, Hui Chen Su, Xiaofeng Zhang, Jun Yang · 2017 · Biochemistry and Cell Biology
Pharmacological modulation of brain activity in a preclinical model of osteoarthritis
Jaymin Upadhyay, Scott J. Baker, Raj Rajagovindan, Michelle Hart, Prasant Chandran, Bradley A. Hooker, S.L. Cassar, Joseph P. Mikusa, Ann E. Tovcimak, Michael Wald et al. · 2012 · NeuroImage
IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice
S. Kour, M. Garimella, D. Shiroor, Suhas T. Mhaske, S. R. Joshi, Kanupriya Singh, Subhashis Pal, M. Mittal, H. Krishnan, N. Chattopadhyay et al. · 2016 · Journal of Immunology
Genetic abrogation of the fibronectin-α5β1 integrin interaction in articular cartilage aggravates osteoarthritis in mice
Maylin Almonte Becerril, Irene Gimeno-LLuch, Olga Villarroya, María Benito-Jardón, Juan Bautista Kouri, Mercedes Costell · 2018 · PLoS ONE
MicroRNA-27b targets CBFB to inhibit differentiation of human bone marrow mesenchymal stem cells into hypertrophic chondrocytes
Shuang Lv, Jinying Xu, Lin Chen, Haitao Wu, Wei Sheng Feng, Yangyang Zheng, Pengdong Li, Haiying Zhang, Lihong Zhang, Guangfan Chi et al. · 2020 · Stem Cell Research & Therapy
Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology
Nanxing Yi, Yilin Mi, Xiaotong Xu, Naping Li, Fan Zeng, Ke Yan, Kaiyun Tan, Gaoyan Kuang, Min M. Lu · 2022 · Frontiers in Pharmacology
C10orf10/DEPP activates mitochondrial autophagy and maintains chondrocyte viability in the pathogenesis of osteoarthritis
Masanari Kuwahara, Yukio Akasaki, Ichiro Kurakazu, Takuya Sueishi, Masakazu Toya, Taisuke Uchida, Tomoaki Tsutsui, Ryota Hirose, Hidetoshi Tsushima, Takeshi Teramura et al. · 2022 · The FASEB Journal
Role of dentin matrix protein 1 in cartilage redifferentiation and osteoarthritis
Indira Prasadam, Yinghong Zhou, Wei Shi, Ross Crawford, Yin Xiao · 2014 · Lara D. Veeken
Controlling Abnormal Joint Movement Inhibits Response of Osteophyte Formation
Kenji Murata, Takanori Kokubun, Yuri Morishita, Katsuya Onitsuka, Shuhei Fujiwara, Aya Nakajima, Tsutomu Fujino, Kiyomi Takayanagi, Naohiko Kanemura · 2017 · Cartilage
Novel perspectives on leptin in osteoarthritis: Focus on aging
Zimo Liu, Wenqing Xie, Hengzhen Li, Xu Liu, Yao Lu, Bangbao Lu, Zhenhan Deng, Yusheng Li · 2023 · Genes & Diseases
WNT Signalling in Osteoarthritis and Its Pharmacological Targeting
Anna De Palma, Giovanna Nalesso · 2021 · Handbook of experimental pharmacology
Cartilage Tissue Engineering: The Role of Extracellular Matrix (ECM) and Novel Strategies
Y. Zaira, David Garciadiego-Cázares, Carmen Parra-Cid, Roco Aguilar-Gaytn, Cristina Velasquillo, Clemente Ibarra, Javier S. Castro Carmo · 2013 · InTech eBooks
Wnt7a Inhibits IL-1β Induced Catabolic Gene Expression and Prevents Articular Cartilage Damage in Experimental Osteoarthritis
Averi L. Gibson, Carrie K. Hui Mingalone, Andrea Foote, Tomoya Uchimura, Ming Zhang, Li Zeng · 2017 · Scientific Reports
Oxytocin prevents cartilage matrix destruction via regulating matrix metalloproteinases
Yixin Wu, Tongyu Wu, Binbin Xu, Xiaoyan Xu, Honggan Chen, Xiyao Li · 2017 · Biochemical and Biophysical Research Communications
Inhibition of the Expression of Matrix Metalloproteinases in Articular Chondrocytes by Resveratrol through Affecting Nuclear Factor-Kappa B Signaling Pathway
Dong-Geun Kang, Hyun Jae Lee, Hyun Jae Lee, Jin Sung Park · 2018 · Biomolecules & Therapeutics
Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3
Anastasios Chanalaris, Christine M. Doherty, Brian D. Marsden, Gabriel Bambridge, Stephen P. Wren, Hideaki Nagase, Linda Troeberg · 2017 · Molecular Pharmacology
Hyaluronic acid alkyl derivative: A novel inhibitor of metalloproteases and hyaluronidases.
M. Pavan, D. Galesso, C. Secchieri, C. Guarise · 2016 · International Journal of Biological Macromolecules
Macrophage phenotypes and monocyte subsets after destabilization of the medial meniscus in mice
Lizette Utomo, Niamh Fahy, Nicole Kops, Sandra T. van Tiel, Jan Hendrik Waarsing, Jan A.N. Verhaar, Pieter J. M. Leenen, Gerjo J.V.M. van Osch, Yvonne M. Bastiaansen-Jenniskens · 2020 · Journal of Orthopaedic Research®
CircHIPK3 prevents chondrocyte apoptosis and cartilage degradation by sponging miR ‐30a‐3p and promoting PON2
Jie Shang, Huizi Li, Biao Wu, Ning Jiang, Bin Wang, Dawei Wang, Junlong Zhong, Yufeng Chen, Xianghe Xu, Huading Lu · 2022 · Cell Proliferation
Cilia protein IFT88 regulates extracellular protease activity by optimizing LRP‐1–mediated endocytosis
Clarissa R. Coveney, Isabella Collins, Megan Mc Fie, Anastasios Chanalaris, Kazuhiro Yamamoto, Angus K. T. Wann · 2018 · The FASEB Journal
Effects of Controlling Abnormal Joint Movement on Expression of MMP13 and TIMP-1 in Osteoarthritis
Katsuya Onitsuka, Kenji Murata, Takanori Kokubun, Shuhei Fujiwara, Aya Nakajima, Yuri Morishita, Naohiko Kanemura · 2018 · Cartilage
Differential patterns of pathology in and interaction between joint tissues in long-term osteoarthritis with different initiating causes: phenotype matters
Sanaa Zaki, Margaret Mary Smith, Susan M. Smith, Christopher B. Little · 2020 · Osteoarthritis and Cartilage
Anti-inflammatory and chondroprotective effects of atorvastatin in a cartilage explant model of osteoarthritis
Nitya Nand Pathak, Madhu Cholenahalli Lingaraju, Venkanna Balaganur, Vinay Kant, Amar S. More, Dhirendra Kumar, Dinesh Kumar, Surendra Kumar Tandan · 2015 · Inflammation Research
Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63
Yuki Taniguchi, Manabu Kawata, Song Ho Chang, Daisuke Mori, Keita Okada, Hiroshi Kobayashi, Shurei Sugita, Yoko Hosaka, Hiroshi Inui, Shuji Taketomi et al. · 2016 · Arthritis & Rheumatology
Transglutaminase-2 regulates Wnt and FoxO3a signaling to determine the severity of osteoarthritis
Min-Su Han, Youn‐Kwan Jung, Gun-Woo Kim, Seung Woo Han · 2020 · Scientific Reports
Yes-Associated Protein 1: Role and Treatment Prospects in Orthopedic Degenerative Diseases
Wenqing Xie, Wenfeng Xiao, Kun Tang, Liyang Zhang, Yusheng Li · 2020 · Frontiers in Cell and Developmental Biology
Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing
Rexhina Vlashi, Xingen Zhang, Haibo Li, Guiqian Chen · 2023 · Reviews in Endocrine and Metabolic Disorders
Long Noncoding RNA Nuclear Enriched Abundant Transcript 1 (NEAT1) Regulates Proliferation, Apoptosis, and Inflammation of Chondrocytes via the miR-181a/Glycerol-3-Phosphate Dehydrogenase 1-Like (GPD1L) Axis
Zengliang Wang, Jianxue Hao, Desheng Chen · 2019 · Medical Science Monitor
COL2A1 and Caspase-3 as Promising Biomarkers for Osteoarthritis Prognosis in an Equus asinus Model
Aya Mohye Yassin, Huda O. AbuBakr, Ahmed Ismael Abdelgalil, Marwa S. Khattab, Adel M. EL-Behairy, Eman M. Gouda · 2020 · Biomolecules
Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes
Sophie J. Gilbert, Emma J. Blain, Ayesha Al‐Sabah, Yong Zhang, VC Duance, Deborah J. Mason · 2012 · European Cells and Materials
Effects of prunetin on the proteolytic activity, secretion and gene expression of MMP-3in vitroand production of MMP-3in vivo
Dae-Cheol Nam, Bo Kun Kim, Hyun Jae Lee, Hyun Dae Shin, Hyun Jae Lee, Sun‐Chul Hwang · 2016 · Korean Journal of Physiology and Pharmacology
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways
Bowei Ni, Xiaojian Huang, Xi Yang, Zekai Mao, Xiangyu Chu, Rui Zhang, Xiaohu Ma, Hongbo You · 2020 · Inflammation
Molecular docking and molecular dynamics to identify collagenase inhibitors as lead compounds to address osteoarthritis
Himadri Shekhar Roy, Gurudutt Dubey, Vishnu Kumar Sharma, Prasad V. Bharatam, Deepa Ghosh · 2020 · Journal of Biomolecular Structure and Dynamics
Yougui Pills Attenuate Cartilage Degeneration via Activation of TGF-β/Smad Signaling in Chondrocyte of Osteoarthritic Mouse Model
Lei Zhang, Pinger Wang, Jun Ying, Xing Yu Jin, Cheng Luo, Taotao Xu, Shibing Xu, Rui Dong, Luwei Xiao, Peijian Tong et al. · 2017 · Frontiers in Pharmacology
Paeoniflorin inhibits IL‑1β‑induced MMP secretion via the NF‑κB pathway in chondrocytes
Pengfei Hu, Fangfang Sun, Lifeng Jiang, Jiapeng Bao, Lidong Wu · 2018 · Experimental and Therapeutic Medicine
SOST Deficiency Aggravates Osteoarthritis in Mice by Promoting Sclerosis of Subchondral Bone
Jingyu Li, Junjie Xue, Yan Jing, Manyi Wang, Rui Shu, Hui Xu, Chaoran Xue, Jie Feng, Peiqi Wang, Ding Bai · 2019 · BioMed Research International
Andrographolide mitigates cartilage damage via miR‐27‐3p‐modulated matrix metalloproteinase13 repression
Shaojian Chen, Zhihuan Luo, Xiaguang Chen · 2020 · The Journal of Gene Medicine
Suppression of discoidin domain receptor 1 expression enhances the chondrogenesis of adipose-derived stem cells
Shun‐Cheng Wu, Hsu-Feng Hsiao, Mei‐Ling Ho, Yung‐Li Hung, Je‐Ken Chang, Gwo‐Jaw Wang, Chau‐Zen Wang · 2015 · American Journal of Physiology-Cell Physiology
Matriptase Induction of Metalloproteinase‐Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms
D. Wilkinson, Angela Kate Habgood, Heather K. Lamb, Paul Thompson, Alastair R. Hawkins, Antoine Désilets, Richard Leduc, Torsten Steinmetzer, Maya Hammami, Melody S. Lee et al. · 2017 · Arthritis & Rheumatology
変形性関節症において、C10orf10/DEPPはミトコンドリアオートファジーを活性化し、軟骨細胞の生存を維持する
正成桑原 · 2022 · Kyushu University Institutional Repository (QIR) (Kyushu University)
A mouse model for chronic pain-induced increase in ethanol consumption
Butler, Ryan K., Knapp, Darin J., Ulici, Veronica, Longobardi, Lara, Loeser, Richard F., Breese, George R. · 2017 · Pain
MicroRNA‑1 regulates the development of osteoarthritis in a Col2a1‑Cre‑ERT2/GFPfl/fl‑RFP‑miR‑1 mouse model of osteoarthritis through the downregulation of Indian hedgehog expression
Xianda Che, Taoyu Chen, Wei Lei, Xiaodong Gu, Yangyang Gao, Shufen Liang, Penghua Li, Dongping Shi, Bin Liang, Chunfang Wang et al. · 2020 · International Journal of Molecular Medicine
Estrogen alleviates post-traumatic osteoarthritis progression and decreases p-EGFR levels in female mouse cartilage
Zhihua Lu, Aihua Zhang, Jingcheng Wang, Kuijing Han, Han Gao · 2022 · BMC Musculoskeletal Disorders
Urokinase-type plasminogen activator and arthritis progression: contrasting roles in systemic and monoarticular arthritis models
Christine M. De Nardo, Jason C. Lenzo, Jarrad Pobjoy, John A. Hamilton, Andrew D. Cook · 2010 · Arthritis Research & Therapy
Insulin-like growth factor-1 engaged in the mandibular condylar cartilage degeneration induced by experimental unilateral anterior crossbite
Dongmei Wang, Hongxu Yang, Mian Zhang, Hongyun Zhang, Lei Lü, Jing Zhang, Xianghong Wan, Meiqing Wang · 2018 · Archives of Oral Biology
Disruption of glucocorticoid signalling in osteoblasts attenuates age-related surgically induced osteoarthritis
J. Tu, P. Zhang, Z S Ji, Holger Henneicke, J. Li, Sarah Kim, Michael M. Swarbrick, Yan Wu, Christopher B. Little, Markus J. Seibel et al. · 2019 · Osteoarthritis and Cartilage
Ultrasound-guided intra-articular injection: efficacy of hyaluronic acid compared to glucocorticoid in the treatment of knee osteoarthritis
Simone Parisi, Maria Chiara Ditto, Marta Priora, Richard Borrelli, Angela Laganà, Clara Lisa Peroni, Enrico Fusaro · 2020 · Minerva Medica
Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang · 2024 · Advanced Healthcare Materials
Therapeutic application of extracellular vesicles for musculoskeletal repair & regeneration
Khairat Bahgat Youssef El Baradie, Mark W. Hamrick · 2020 · Connective Tissue Research
Indirubin protects chondrocytes and alleviates OA by inhibiting the MAPK and NF-κB pathways
Xiaolin Wang, Zhou Guo, Jiamin Lin, Kai Sun, Genchun Wang, Liangcai Hou, Jingting Xu, Jiachao Guo, Xiong Zhang, Fengjing Guo et al. · 2022 · International Immunopharmacology
Disease-modifying interactions between chronic kidney disease and osteoarthritis: a new comorbid mouse model
Sohel M. Julovi, Aiken Dao, Katie Trinh, Alexandra K O’Donohue, Cindy C. Shu, Susan M. Smith, Meena V. Shingde, Aaron Schindeler, Natasha M. Rogers, Christopher B. Little · 2023 · RMD Open
Predisposal of Interferon Regulatory Factor 1 Deficiency to Accumulate DNA Damage and Promote Osteoarthritis Development in Cartilage
Yongsik Cho, Hyeonkyeong Kim, Geunho Yook, Sangmin Yong, Soy Kim, Narae Lee, Yi‐Jun Kim, Jin‐Hee Kim, Tae‐Woo Kim, Moon Jong Chang et al. · 2024 · Arthritis & Rheumatology
Hypoxia-inducible factor-2α induces expression of type X collagen and matrix metalloproteinases 13 in osteoarthritic meniscal cells
Shinya Ishizuka, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Warren Knudson, Takaaki Omachi, Yohei Ono, Motoshige Nakashima, Tetsuya Matsukawa, Tomoyuki Oda et al. · 2016 · Inflammation Research
Induction of Matrix Metalloproteinases in Chondrocytes by Interleukin IL-1β as an Osteoarthritis Model
Ervi Afifah, T. Mozef, F. Sandra, Seila Arumwardana, Dwi Davidson Rihibiha, Hayatun Nufus, R. Rizal, Annisa Amalia, Indra Bachtiar, H. Murti et al. · 2019 · Journal of Mathematical and Fundamental Sciences
Selective MMP13 inhibitors
Jie Jack Li, Adam R. Johnson · 2010 · Medicinal Research Reviews
Proteoglycan and Collagen Degradation in Osteoarthritis
Stephanie J. Gauci, H. Stanton, C. Little, A. Fosang · 2017 · Springer eBooks
Mechanical loading of joint modulates T cells in lymph nodes to regulate osteoarthritis
Tibra A. Wheeler, Adrien Y. Antoinette, Eshant Bhatia, Matthew Kim, Chiemezue N. Ijomanta, Ann Zhao, Marjolein C. H. van der Meulen, Ankur K. Singh · 2023 · Osteoarthritis and Cartilage
Mithramycin A Alleviates Osteoarthritic Cartilage Destruction by Inhibiting HIF-2α Expression
Moon‐Chang Choi, Woo Hee Choi · 2018 · International Journal of Molecular Sciences
Anti-Osteoarthritic Mechanisms of Chrysanthemum zawadskii var. latilobum in MIA-Induced Osteoarthritic Rats and Interleukin-1β-Induced SW1353 Human Chondrocytes
Jae‐Hyuk Byun, Chi-Won Choi, Min-Jung Jang, Su Hwan Lim, Hae Jung Han, Se‐Young Choung · 2020 · Medicina
Deletion of Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization (HYBID) Results in Attenuation of Osteoarthritis in Mice
Masahiro Momoeda, Susana de Vega, Haruka Kaneko, Chiho Yoshinaga, Masayuki Shimoda, Tomomi Nakamura, Yoko Endo, Hiroyuki Yoshida, Kazuo Kaneko, Muneaki Ishijima et al. · 2021 · American Journal Of Pathology
Surgical Induction of Posttraumatic Osteoarthritis in the Mouse
Daisuke Hamada, Erik R. Sampson, Robert D. Maynard, Michael J. Zuscik · 2014 · Methods in molecular biology
Layer dependence in strain distribution and chondrocyte damage in porcine articular cartilage exposed to excessive compressive stress loading
Wenjing Huang, Mia Warner, Hikaru Sasaki, Katsuko Sakai Furukawa, Takashi Ushida · 2020 · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
Articular Cartilage Regeneration via Induced Chondrocyte Autophagy by Sustained Release of Leptin Inhibitor from Thermo‐Sensitive Hydrogel through STAT3/REDD1/mTORC1 Cascade
Zhongming Huang, Chen Liu, Guangping Zheng, Liang Zhang, Qiang Zhong, Yun Zhang, Weicheng Zhao, Yiying Qi · 2023 · Advanced Healthcare Materials
In vivo optical imaging of early osteoarthritis using an antibody specific to damaged arthritic cartilage
Ngee Han Lim, Tonia L. Vincent, Ahuva Nissim · 2015 · Arthritis Research & Therapy
Hyaluronic Acid Suppresses the Expression of Metalloproteinases in Osteoarthritic Cartilage Stimulated Simultaneously by Interleukin 1β and Mechanical Load
Florian Pohlig, Florian Guell, Ulrich Lenze, Florian Walter Lenze, H. Mühlhofer, Johannes Schauwecker, Andreas Toepfer, Philipp Mayer‐Kuckuk, Rüdiger von Eisenhart‐Rothe, Rainer Burgkart et al. · 2016 · PLoS ONE
Novel therapeutic targets in osteoarthritis: Narrative review on knock-out genes involved in disease development in mouse animal models
Francesca Veronesi, Elena Della Bella, Simona Cepollaro, Silvia Brogini, Lúcia Martini, Milena Fini · 2016 · Cytotherapy
Inducible knockout of CHUK/IKKα in adult chondrocytes reduces progression of cartilage degradation in a surgical model of osteoarthritis
Kirsty L. Culley, Samantha G. Lessard, Jordan D. Green, Justin Quinn, Jun Chang, Tyler K. Khilnani, Elisabeth B. Wondimu, Cecilia L. Dragomir, Kenneth B. Marcu, Mary B. Goldring et al. · 2019 · Scientific Reports
N-O-Isopropyl sulfonamido-based hydroxamates: Kinetic characterisation of a series of MMP-12/MMP-13 dual target inhibitors
Salvatore Santamaria, Elisa Nuti, Giovanni Cercignani, Luciana Marinelli, Valeria La Pietra, Ettore Novellino, Armando Rossello · 2012 · Biochemical Pharmacology
Mouse Models of Osteoarthritis: Surgical Model of Post-traumatic Osteoarthritis Induced by Destabilization of the Medial Meniscus
Kirsty L. Culley, Purva Singh, Samantha G. Lessard, Mengying Wang, Brennan J. Rourke, Mary B. Goldring, Miguel Otero · 2020 · Methods in molecular biology
Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non‐Amplification of Activin A‐ACVR2B‐NOX4 Axis Pathway
Jimin Jeon, Hye‐Mi Lee, Min‐Seung Jeon, Seok‐Jung Kim, Cham Albert Choi, Ki Woo Kim, Dong Joo Yang, Sangho Lee, Yong‐Soo Bae, Won Il Choi et al. · 2023 · Advanced Science
Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-5
Aya Miyauchi, Joo‐ri Kim‐Kaneyama, Xiao‐Feng Lei, Song Ho Chang, Taku Saito, Shogo Haraguchi, Takuro Miyazaki, Akira Miyazaki · 2019 · Scientific Reports
Histone H3K9 methylation is involved in�temporomandibular joint osteoarthritis
万由美浮田, Kenji Matsushita, Masato Tamura, Taihiko Yamaguchi · 2019 · International Journal of Molecular Medicine
Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
Taku Ebata, Mohamad Alaa Terkawi, Masanari Hamasaki, Gen Matsumae, Tomohiro Onodera, Mahmoud Khamis Aly, Shunichi Yokota, Hend Alhasan, Tomohiro Shimizu, Daisuke Takahashi et al. · 2021 · iScience
Pathogenesis of Osteoarthritis
Paul E. Di Cesare, Dominik R. Haudenschild, Jonathan Samuels, Steven B. Abramson · 2016 · Elsevier eBooks
Exploring the Mechanism of Resveratrol in Reducing the Soft Tissue Damage of Osteoarthritis Based on Network Pharmacology and Experimental Pharmacology
Zhiyong Long, Xiang Wang, Jun Li, Tiejun Yang, Ganpeng Yu · 2021 · Evidence-based Complementary and Alternative Medicine
Promotion of Knee Cartilage Degradation by IκB Kinase ε in the Pathogenesis of Osteoarthritis in Human and Murine Models
Taisuke Uchida, Yukio Akasaki, Takuya Sueishi, Ichiro Kurakazu, Masakazu Toya, Masanari Kuwahara, Ryota Hirose, Yuki Hyodo, Hidetoshi Tsushima, Martin Lotz et al. · 2022 · Arthritis & Rheumatology
Protease-Activatable Porphyrin Molecular Beacon for Osteoarthritis Management
Connor D. Walsh, Maneesha A. Rajora, Lili Ding, Sayaka Nakamura, Helal Endisha, Jason S. Rockel, Juan Chen, Mohit Kapoor, Gang Zheng · 2023 · Chemical & Biomedical Imaging
Prebiotics alleviate cartilage degradation and inflammation in post-traumatic osteoarthritic mice by modulating the gut barrier and fecal metabolomics
Yilin Mi, Nanxing Yi, Xiaotong Xu, Fan Zeng, Naping Li, Xuyi Tan, Zhixian Gong, Ke Yan, Gaoyan Kuang, Min Lü · 2023 · Food & Function