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Cited by 454

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The MyoD family of transcription factors and skeletal myogenesis

Rudnicki, Michael A., Jaenisch, Rudolf·1995·BioEssays

Abstract

Gene targeting has allowed the dissection of complex biological processes at the genetic level. Our understanding of the nuances of skeletal muscle development has been greatly increased by the analysis of mice carrying targeted null mutations in the Myf‐5, MyoD and myogenin genes, encoding members of the myogenic regulatory factor (MRF) family. These experiments have elucidated the hierarchical relationships existing between the MRFs, and established that functional redundancy is a feature of the MRF regulatory network. Either MyoD or Myf‐5 is sufficient for the formation or survival of skeletal myoblasts. Myogenin acts later in development and plays an essential in vivo role in the terminal differentiation of myotubes.

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Metadata

Authors
Rudnicki, M. A., & Jaenisch, R.
Venue
BioEssays
Publisher
Wiley
Published
1995-03
Volume
17
Issue
3
Pages
203-209
ISSN
  • 0265-9247 (ISSN-L)
  • 1521-1878
OpenAlex
W1971314280
Cited by
454
References
2
FWCI
2.06
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The MyoD family of transcription factors and skeletal myogenesis. https://app.cochat.ai/papers/10.1002/bies.950170306
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Rudnicki, M. A., & Jaenisch, R. (1995). The MyoD family of transcription factors and skeletal myogenesis. BioEssays. https://doi.org/10.1002/bies.950170306

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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