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Cited by 308

The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.

Therapeutic bacteria to combat cancer; current advances, challenges, and opportunities

Open access
Sedighi, Mansour, Zahedi Bialvaei, Abed, Hamblin, Michael R., Ohadi, Elnaz, Asadi, Arezoo, Halajzadeh, Masoumeh, Lohrasbi, Vahid, Mohammadzadeh, Nima, Amiriani, Taghi, Krutova, Marcela, Amini, Abolfazl, Kouhsari, Ebrahim·2019·Cancer Medicine
DOI 10.1002/cam4.2148
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Abstract

Successful treatment of cancer remains a challenge, due to the unique pathophysiology of solid tumors, and the predictable emergence of resistance. Traditional methods for cancer therapy including radiotherapy, chemotherapy, and immunotherapy all have their own limitations. A novel approach is bacteriotherapy, either used alone, or in combination with conventional methods, has shown a positive effect on regression of tumors and inhibition of metastasis. Bacteria‐assisted tumor‐targeted therapy used as therapeutic/gene/drug delivery vehicles has great promise in the treatment of tumors. The use of bacteria only, or in combination with conventional methods was found to be effective in some experimental models of cancer (tumor regression and increased survival rate). In this article, we reviewed the major advantages, challenges, and prospective directions for combinations of bacteria with conventional methods for tumor therapy.

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Registry

Crossref · 10.1002/cam4.2148

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Metadata

Authors
Sedighi, M., Zahedi Bialvaei, A., Hamblin, M. R., Ohadi, E., Asadi, A., Halajzadeh, M., Lohrasbi, V., Mohammadzadeh, N., Amiriani, T., Krutova, M., Amini, A., & Kouhsari, E.
Venue
Cancer Medicine
Publisher
Wiley
Published
2019-04-05
Volume
8
Issue
6
Pages
3167-3181
ISSN
2045-7634 (ISSN-L)
DOI
10.1002/cam4.2148
OpenAlex
W2925402322
Cited by
308
References
150
FWCI
16.87
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Therapeutic bacteria to combat cancer; current advances, challenges, and opportunities. https://app.cochat.ai/papers/10.1002/cam4.2148
The paper
Sedighi, M., Zahedi Bialvaei, A., Hamblin, M. R., Ohadi, E., Asadi, A., Halajzadeh, M., Lohrasbi, V., Mohammadzadeh, N., Amiriani, T., Krutova, M., Amini, A., & Kouhsari, E. (2019). Therapeutic bacteria to combat cancer; current advances, challenges, and opportunities. Cancer Medicine. https://doi.org/10.1002/cam4.2148

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.