The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Worms, Life, and Death (Nobel Lecture)
Abstract
The life versus death fate of a cell is decided by a genetic programme that controls cell death, as was discovered by studying Caenorhabditis elegans. The first two “killer genes” to be discovered were ced-3 and ced-4, both of which must be functional for cell death to be executed. Another gene, ced-9, protects against cell death by interacting with ced-4 and ced-3 (see scheme). For most genes involved in controlling cell death in C. elegans there exists a corresponding human gene and such genes are evolutionarily well conserved.
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Cites
Identification of Novel Genes Coding for Small Expressed RNAs
Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956
The embryonic cell lineage of the nematode Caenorhabditis elegans
Sulston, J. E., Schierenberg, E., White, J. G., & Thomson, J. N. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90201-4 · Cited by 4,199
The Bcl2 family: regulators of the cellular life-or-death switch
Cory, S., & Adams, J. M. (2002) · Nature Reviews Cancer · doi:10.1038/nrc883 · Cited by 4,032
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
Friend, S. H., Bernards, R., Rogelj, S., Weinberg, R. A., Rapaport, J. M., Albert, D. M., & Dryja, T. P. (1986) · Nature · doi:10.1038/323643a0 · Cited by 2,948
Genetic control of programmed cell death in the nematode C. elegans
Ellis, H. (1986) · Cell · doi:10.1016/0092-8674(86)90004-8 · Cited by 1,828
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Heterochronic Mutants of the Nematode Caenorhabditis elegans
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Self-citation
Cited by
Molecular mechanisms of caspase regulation during apoptosis
Riedl, S. J., & Shi, Y. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1496 · Cited by 1,899
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
Kim, H., Rafiuddin-Shah, M., Tu, H.-C., Jeffers, J. R., Zambetti, G. P., Hsieh, J. J.-D., & Cheng, E. H.-Y. (2006) · Nature Cell Biology · doi:10.1038/ncb1499 · Cited by 874
Caspase-independent cell death
Kroemer, G., & Martin, S. J. (2005) · Nature Medicine · doi:10.1038/nm1263 · Cited by 716
Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt
Robey, R. B., & Hay, N. (2006) · Oncogene · doi:10.1038/sj.onc.1209595 · Cited by 536
Li, F., Huang, Q., Chen, J., Peng, Y., Roop, D. R., Bedford, J. S., & Li, C.-Y. (2010) · Science Signaling · doi:10.1126/scisignal.2000634 · Cited by 494
Metadata
- Authors
- Horvitz, H. R.
- Venue
- ChemBioChem
- Publisher
- Wiley
- Published
- 2003-07-28
- Volume
- 4
- Issue
- 8
- Pages
- 697-711
- ISSN
- 1439-4227 (ISSN-L)
- 1439-7633
- OpenAlex
- W1521408068
- Cited by
- 172
- References
- 7
- FWCI
- 3.97
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
